Yes! Recent research suggests that a fasting-mimicking diet (FMD)—a short-term, low-calorie, low-protein, high-fat dietary intervention designed to mimic the effects of fasting—may help improve blood sugar control in individuals with type 2 diabetes (T2D) while minimizing risks associated with prolonged fasting.

Key Findings on FMD & Blood Sugar Control:

1. Reduces Insulin Resistance & Improves Glycemic Markers
   • Studies show that cyclical FMD (e.g., 5-day monthly cycles) can lower fasting glucose, HbA1c, and insulin resistance (HOMA-IR).
   • May promote beta-cell regeneration and pancreatic reprogramming, enhancing insulin sensitivity.
2. Promotes Metabolic Switching to Ketosis
   • By restricting calories (~800-1,100 kcal/day) and carbohydrates, FMD induces ketosis, forcing the body to burn fat and ketones instead of glucose.
   • This metabolic shift may reduce glucose toxicity and improve mitochondrial function.
3. Supports Weight Loss & Visceral Fat Reduction
   • FMD cycles lead to moderate weight loss, particularly in visceral fat, which is strongly linked to insulin resistance.
   • Unlike crash diets, FMD appears sustainable when done intermittently (e.g., once a month).
4. Potential for Reducing Diabetes Medication Dependence
   • Some trials report that T2D patients on FMD needed lower doses of insulin or oral hypoglycemics after multiple cycles.
   • Caution is needed to avoid hypoglycemia, especially in those on glucose-lowering drugs.

How FMD Works in Diabetes:

• Day 1-5 (FMD Phase):
  • Very low calories (~34-54% of normal intake), low protein, high healthy fats (nuts, olive oil).
  • Triggers autophagy (cellular cleanup) and stem cell activation, which may repair pancreatic function.
• Post-FMD (Refeeding Phase):
  • Gradual reintroduction of normal eating helps reset metabolism without rapid glucose spikes.

Clinical Evidence:

• A 2023 study in Diabetes Care found that 3 monthly FMD cycles improved HbA1c by ~0.5–1.2% in prediabetics and early T2D patients.
• Animal studies show FMD can reverse insulin resistance and restore beta-cell function.

Safety & Considerations:

• Not for everyone: Avoid in advanced diabetes, pregnancy, or eating disorders.
• Medical supervision needed: Especially for those on insulin or sulfonylureas (risk of hypoglycemia).
• Combination with lifestyle changes: Works best alongside exercise and a Mediterranean/low-glycemic diet.

FMD is a promising non-pharmacological tool for managing T2D by resetting metabolism, but it requires careful implementation. Future studies will clarify long-term benefits and optimal protocols.

Reference:

https://www.medicalnewstoday.com/articles/a-fasting-mimicking-diet-may-improve-blood-sugar-control-in-type-2-diabetes

https://pubmed.ncbi.nlm.nih.gov/38546821

https://www.annfammed.org/content/21/Supplement_3/5005

Medications that have been suggested by doctors worldwide are available on below link

https://mygenericpharmacy.com/category/disease/diabetes