{"id":8256,"date":"2025-07-23T13:39:56","date_gmt":"2025-07-23T13:39:56","guid":{"rendered":"https:\/\/blog.mygenericpharmacy.com\/?p=8256"},"modified":"2025-07-23T13:40:00","modified_gmt":"2025-07-23T13:40:00","slug":"weekly-injection-could-be-life-changing-for-parkinsons-patients","status":"publish","type":"post","link":"https:\/\/blog.mygenericpharmacy.com\/index.php\/2025\/07\/23\/weekly-injection-could-be-life-changing-for-parkinsons-patients\/","title":{"rendered":"Weekly injection could be life changing for Parkinson\u2019s patients"},"content":{"rendered":"\n<p>Exciting news in <strong>Parkinson\u2019s disease (PD) treatment<\/strong>! A <strong>new weekly subcutaneous injection<\/strong> is showing promise in clinical trials, potentially <strong>replacing daily oral medications<\/strong> for some patients.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Key Highlights:<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Drug Name<\/strong>: <strong>ND0612<\/strong> (developed by <strong>NeuroDerm<\/strong>, now part of <strong>AbbVie<\/strong>)<\/li>\n\n\n\n<li><strong>How It Works<\/strong>: A <strong>continuous, subcutaneous infusion of levodopa\/carbidopa<\/strong> (the gold-standard PD treatment), delivering <strong>stable drug levels<\/strong> to avoid motor fluctuations.<\/li>\n\n\n\n<li><strong>Weekly vs. Daily<\/strong>: Unlike traditional <strong>oral levodopa<\/strong> (taken 3-5 times daily), ND0612 is administered via a <strong>small pump<\/strong> worn on the body, requiring only <strong>weekly refills<\/strong>.<\/li>\n\n\n\n<li><strong>Benefits<\/strong>:\n<ul class=\"wp-block-list\">\n<li>Reduces <strong>&#8220;off&#8221; periods<\/strong> (when medication wears off)<\/li>\n\n\n\n<li>Minimizes <strong>dyskinesia<\/strong> (involuntary movements caused by fluctuating drug levels)<\/li>\n\n\n\n<li>Improves <strong>quality of life<\/strong> by simplifying treatment.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Clinical Trial Results<\/strong>:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Phase 3 (BouNDless trial)<\/strong>: Showed <strong>significant reduction in &#8220;off&#8221; time<\/strong> compared to oral levodopa.<\/li>\n\n\n\n<li><strong>FDA Status<\/strong>: Under <strong>priority review<\/strong>, with a decision expected in <strong>2024 or early 2025<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Who Could Benefit?<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PD patients with <strong>advanced symptoms<\/strong> and <strong>motor fluctuations<\/strong> despite oral meds.<\/li>\n\n\n\n<li>Those struggling with <strong>pill fatigue<\/strong> or <strong>absorption issues<\/strong> (common in later-stage PD).<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Challenges Ahead<\/strong>:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cost &amp; Insurance Coverage<\/strong>: Likely expensive initially.<\/li>\n\n\n\n<li><strong>Adoption<\/strong>: Requires patient training on pump use.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Future of PD Treatment<\/strong>:<\/h3>\n\n\n\n<p>If approved, ND0612 could join other <strong>advanced PD therapies<\/strong> like:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Continuous intestinal gel (Duodopa\/Duopa)<\/strong><\/li>\n\n\n\n<li><strong>Deep brain stimulation (DBS)<\/strong><\/li>\n\n\n\n<li><strong>Monthly\/subcutaneous infusions (e.g., ABBV-951)<\/strong><\/li>\n<\/ul>\n\n\n\n<p><strong>Reference:<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/parkinsons-new-weekly-injection-may-eliminate-need-daily-pills\">https:\/\/www.medicalnewstoday.com\/articles\/parkinsons-new-weekly-injection-may-eliminate-need-daily-pills<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.unisa.edu.au\/media-centre\/Releases\/2025\/weekly-injection-could-be-life-changing-for-parkinsons-patients\">https:\/\/www.unisa.edu.au\/media-centre\/Releases\/2025\/weekly-injection-could-be-life-changing-for-parkinsons-patients<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/timesofindia.indiatimes.com\/life-style\/health-fitness\/health-news\/one-shot-a-week-how-weekly-parkinsons-injection-would-be-a-game-changer-for-patients\/articleshow\/122480019.cms\">https:\/\/timesofindia.indiatimes.com\/life-style\/health-fitness\/health-news\/one-shot-a-week-how-weekly-parkinsons-injection-would-be-a-game-changer-for-patients\/articleshow\/122480019.cms<\/a><\/p>\n\n\n\n<p>Medications that have been suggested by doctors worldwide are available on below link<\/p>\n\n\n\n<p><a href=\"https:\/\/mygenericpharmacy.com\/category\/disease\/parkinsons-disease\">https:\/\/mygenericpharmacy.com\/category\/disease\/parkinsons-disease<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Exciting news in Parkinson\u2019s disease (PD) treatment! A new weekly subcutaneous injection is showing promise in clinical trials, potentially replacing daily oral medications for some patients. Key Highlights: Clinical Trial Results: Who Could Benefit? Challenges Ahead: Future of PD Treatment: If approved, ND0612 could join other advanced PD therapies like: Reference: https:\/\/www.medicalnewstoday.com\/articles\/parkinsons-new-weekly-injection-may-eliminate-need-daily-pills https:\/\/www.unisa.edu.au\/media-centre\/Releases\/2025\/weekly-injection-could-be-life-changing-for-parkinsons-patients https:\/\/timesofindia.indiatimes.com\/life-style\/health-fitness\/health-news\/one-shot-a-week-how-weekly-parkinsons-injection-would-be-a-game-changer-for-patients\/articleshow\/122480019.cms Medications that have been suggested by doctors worldwide are available on below link https:\/\/mygenericpharmacy.com\/category\/disease\/parkinsons-disease<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[3632],"tags":[],"class_list":["post-8256","post","type-post","status-publish","format-standard","hentry","category-parkinsons"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/posts\/8256","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/comments?post=8256"}],"version-history":[{"count":1,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/posts\/8256\/revisions"}],"predecessor-version":[{"id":8257,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/posts\/8256\/revisions\/8257"}],"wp:attachment":[{"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/media?parent=8256"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/categories?post=8256"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.mygenericpharmacy.com\/index.php\/wp-json\/wp\/v2\/tags?post=8256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}