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Cancer: physical activity a day could lower your risk.

Cancer: physical activity a day could lower your risk.

In a recent study, the impact of vigorous intermittent lifestyle physical activity (VILPA) on the risk of developing cancer was examined.

Using information from wrist-worn accelerometers, researchers followed 22,398 non-exercisers’ health records for cancer for nearly 7 years while also tracking their daily intense activity.

When compared to not participating in VIPLA, 4.5 minutes of VILPA per day, divided into 1-minute bursts, was linked to a 32% lower chance of developing cancer.

Power walking, lugging groceries, and climbing stairs are just a few examples of the many possibilities that exist in daily life for strenuous physical activity.

The importance of physical activity to overall health and wellbeing cannot be overstated. According to research, regular exercise can reduce the risk of developing chronic diseases like cancer, diabetes, and cardiovascular disease.

In fact, the World Health Organisation (WHO) reports that those who are not adequately active have a death risk that is 20–30% higher than those who are.

Even though the benefits of physical activity are obvious, only about 1 in 3 women and 1 in 4 men globally adhere to the guidelines for 75 minutes of strenuous exercise or at least 150 minutes of moderate exercise per week.

Good news has arrived from a recent study for those who dislike or are unable to engage in structured, intense exercise.

Just 4.5 minutes per day of vigorous-intensity physical exercise undertaken in 1-minute bursts was related with an up to 32% decreased risk of cancer, according to wrist-worn accelerometer data taken from 22,398 non-exercising people collected from the UK Biobank.

VILPA: What is it?

Short bursts of physical activity that are a regular component of our lifestyle (daily living) are referred to as vigorous intermittent lifestyle physical activity (VILPA) by Dr. Stamatakis and his colleagues.

VILPA examples include, but are not restricted to:

  • climbing hills
  • ascending stairs
  • power walking, also known as maximising walking pace for a short distance (like 100–200 metres) to reach intense intensity, involves carrying children or groceries for 50–100 metres.
  • intense housework.
  • VILPA differs from conventional intense physical activity in that it is intermittent and transient, lasting up to two minutes at a time, as opposed to continuous and planned.

Effects of VILPA and cancer risk

The study was a prospective cohort study of adults, aged 40 to 69, who provided the UK Biobank with their data.

The research team led by Dr. Stamatakis only included participants from the accelerometer-wearing group who reported not exercising in their free time and taking one or fewer leisurely walks per week in their analysis of the association between VILPA and cancer incidence.

The study removed participants who provided incomplete information, had a history of cancer, or improperly wore the activity monitor.

22,398 participants made up the study population, and their average age was 62. 54.8% of these were female, and 96% of them were white.

The researchers found 2,356 new cancer occurrences throughout a mean follow-up period of 6.7 years, including cancer registration, hospitalisation for cancer, or death from any malignancy.

The researchers utilised a machine-learning method known as “random forest” to categorise accelerometer-recorded physical activity based on intensity — vigorous, moderate, and light.

VILPA reduces cancer risk by just a few minutes every day.

The majority of VILPA incidents took place in spurts of up to one or two minutes. People participated in VILPA for a maximum of 16 minutes, or about 4.5 minutes per day on average.

According to statistical assessments, the association between VILPA and cancer risk is almost linear, meaning that a person’s risk of developing cancer decreases as they engage in more VILPA.

People who engaged in VILPA for an average of 4.5 minutes per day, in short bursts of up to 1 or 2 minutes, had a 20% lower chance of developing cancer than those who did not engage in any VILPA (6.2% of study participants).

Previous studies have demonstrated a link between insufficient physical activity and several cancer forms. These consist of:

  • liver
  • lung
  • kidney
  • gastric cardia (a type of stomach cancer)
  • endometrial
  • Leukaemia myeloid
  • myeloma
  • colorectal
  • neck and head
  • bladder
  • mammary cancer
  • esophageal adenocarcinoma (esophageal cancer)

This study demonstrates that those who engaged in 4.5 minutes of VILPA daily have a 31% lower risk of developing certain physical activity-related malignancies.

The least amount of VILPA necessary to significantly lower the chance of developing cancer was also determined by the researchers. They discovered that 3.4 minutes of VILPA per day can reduce the risk of cancer overall by 17% and 3.6 minutes of VILPA per day can reduce the risk of cancer linked to physical activity by 18%.

More study is required to determine how VILPA affects cancer.

A relatively small quantity of strenuous lifestyle activity can have such a large link with decreased cancer risk, according to the “high-quality study,” according to Dr. David Raichlen, professor of biological sciences and anthropology at the University of Southern California.

According to him, “the authors used a novel machine learning-based method to identify behaviours and this study moves the field forward, allowing us to better understand the benefits of this form of physical activity on [the] risk of developing cancer.”

Because of the study’s methodology, Dr. Raichlen advised that causality could not be established; however, “this work certainly suggests that future intervention studies using VILPA are warranted.”

According to Prof. Markus Gruber, chair of Training and Movement Science and director of the University Konstanz’s Human Performance Research Centre, the study supports the long-held belief in exercise science that “intensity matters.”

Prof. Gruber made the same observation as Dr. Raichlen, namely that although the study’s data, methods, and analysis are sound, the study is cross-sectional and can only report relationships between VILPA and cancer incidence.

When challenged about the connection between VILPA and cancer incidence, Prof. Gruber responded that there are a number of plausible “explanations for the results that need to be tested.”

He claims that VILPA may either directly lower the risk of cancer, boost physical fitness, or show superior physical fitness, which is linked to a lower risk of cancer. Additionally, VILPA may reduce the effects of aging-related fitness decreases and reduce cancer risk by doing so.

Overall, according to Prof. Gruber, VILPA is a promising substitute for duration-based advice on physical activity, “especially for people who don’t like to exercise.”

REFERENCES:

For Cancer disease medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?therapy=10

Are brain fog, sleep, and pain improved by Cannabis?

Are brain fog, sleep, and pain improved by Cannabis?

Cannabis, according to researchers, may be able to lessen the negative effects of chemotherapy as well as cancer discomfort. In a recent study, cancer patients said that using cannabis helped them feel less pain, sleep better, and think more clearly.

According to experts, federal rules need to be altered so that more studies may be done on cannabis’ advantages and impacts on medical ailments.

According to a study conducted at the University of Colorado at Boulder and published in the journal Exploration in Medicine, people with cancer who use cannabis to alleviate symptoms experience less pain, sleep better, and have clearer thinking.

This is one of the first observational studies to examine the potential effects of cannabis products obtained from a dispensary on chemotherapy side effects and cancer symptoms.

University researchers are only permitted to possess and distribute cannabis products that are authorized by the government or that meet pharmaceutical standards in the United States, which makes it challenging to conduct studies on dispensary goods.

The researchers at the University of Colorado, however, developed a novel strategy. When 25 cancer patients bought their products, they watched how they responded.

During a baseline visit, the researchers evaluated the patient’s pain tolerance, sleep quality, and cognitive function. After that, the participants went to a dispensary and bought a cannabis edible product of their choice. They selected several different products, such as:

  • Chocolates
  • Gummies
  • Tinctures
  • Pills
  • a baked good

Additionally, the THC and CBD potencies varied widely.

Information from the cannabis and cancer pain study

The researchers traveled to each person’s residence in a mobile lab.

Before being asked to consume the cannabis product they had chosen at home, each person had their physical and mental capabilities evaluated in the van. After consuming medical marijuana, they completed another test.

Within an hour of using the items, the patients claimed that their pain levels had greatly decreased. Additionally, it made them feel “high” and affected their cognitive function. They claimed to feel higher the more THC was present.

After two weeks of consistent use, the individuals underwent a follow-up examination. At that time, the patients indicated that their pain, sleep, and cognitive abilities had all decreased. Improvements were evident in various cognitive domains, including reaction times, according to objective measurements.

The researchers found that lower levels of pain led to an improvement in cognitive performance. The improvement in cognition increased as the discomfort decreased.

Patients who consumed more CBD reported significant reductions in pain and better sleep. CBD reduces inflammation. The authors of the study point out that while cognition was temporarily reduced, it can be enhanced by treating pain.

How cannabis might benefit cancer patients

Some dosages and cannabis types, according to experts, may be beneficial for persons receiving cancer therapy.

Dr. Wael Harb, a hematologist and medical oncologist at Memorial Care Cancer Institute at Orange Coast Medical Centre in California who was not involved in the study, said, “This study adds to the growing body of research that examines the potential benefits of cannabis use in cancer patients.”

According to Harb, “the results highlight the potential for cannabis to reduce pain, enhance cognition, and improve the overall quality of life for patients.” These findings have important therapeutic ramifications since they imply that cannabis may be used as an auxiliary or alternative therapy for cancer patients, particularly those who are in pain or have cognitive deficits.

However, “it is important to note that the study has limitations, such as a relatively small sample size, which may not represent the larger population of cancer patients,” the author continued.

The study also uses self-reported information, which is prone to bias. To validate these results and investigate any potential hazards or negative consequences related to cannabis usage in cancer patients, additional research with bigger, more diverse samples and more objective assessment technologies is required.

What do you need to understand about medical marijuana?

The director of the UCI Centre for the Study of Cannabis, Daniele Piomelli, Ph.D., stated that “this small study supports what oncologists have known for a long time: many cancer patients (half of them, according to some surveys) use cannabis to cope with nausea, pain, and sleeplessness caused by cancer drugs“.

He informed us that the National Cancer Institute, a division of the National Institutes of Health, is aware of this and that urgently required larger investigations are about to begin.

According to the National Institutes of Health, the cannabis plant has two major compounds (cannabinoids) that are employed in medical procedures. THC and CBD are these.

These have not been given use approval by the Food and Drug Administration. The group has, however, approved a small number of drugs that do:

  • Cannabidiol (Epidolex)
  • Dronabinol (Marinol, Syndros)
  • Nabilone

Currently, marijuana use is either decriminalized or legal in 46 states. Anyone considering using medical items should first examine the regulations in their locality as each state has different legislation.

Dr. Olivia Seecof, clinical assistant professor of medicine and attending physician in supportive oncology at NYU Langone Perlmutter Cancer Centre in New York, said she was “very excited” about the study because it was “one of the first studies to address some of the issues surrounding recommending medical cannabis products in an evidence-based way.”

During outpatient supportive oncology appointments, I do certify patients for medical cannabis. I had to enroll in the New York State Medical Cannabis Programme and complete further training/certification to be able to do that,” she explained to us.

The market for medical marijuana is expanding.

Its US market value in 2021 was close to $27 billion. Market Research Future estimates that by 2030, it would reach $248 billion.

According to a Reuters article, some proposed measures in Congress would decriminalize or legalize marijuana.

It would be decriminalized under one statute, leaving state regulation to their discretion. More research will be possible thanks to the regulation reform, giving doctors and other healthcare providers the data they need to treat patients.

Because of cannabis’ murky legal status and negative connotations, many doctors are still uneasy about marijuana, according to Piomelli. “But the profession can no longer bury its head in the sand with so many patients using it. To better meet the requirements of their patients, doctors, nurses, and other medical professionals need to have more knowledge about the advantages and drawbacks of cannabis.

REFERENCES:

For Mental disease medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?cPath=77_478

Migraines increase the chance of problems during pregnancy.

Migraines increase the chance of problems during pregnancy.

A sizable prospective study was carried out by scientists at Brigham and Women’s Hospital in Boston to learn more about the link between migraines and unfavorable pregnancy outcomes.

According to their findings, women with pre-pregnancy headaches had a 40% increased risk of preeclampsia, a 28% increased risk of gestational hypertension, and a 17% increased risk of premature delivery.

These findings, according to the researchers, point to the potential advantage of greater monitoring for pregnant women who have a history of migraines.

Compared to men, women have a 2 to 3 times higher lifetime risk of developing migraines, which are most prevalent in women between the ages of 18 and 44.

Before a migraine attack, some people see an “aura” that frequently consists of flashing lights in their range of vision.

An aura-specific migraine, in particular, has been linked to a two-fold increased risk of myocardial infarction and stroke, according to a recent meta-analysis.

The molecular factors linked to cardiovascular risks in migraine sufferers may also raise the chance of pregnancy difficulties, according to a research hypothesis.

Meanwhile, little research has examined the connection between migraine and difficulties during pregnancy. Small study populations, a lack of knowledge about potential confounding variables, and the migraine phenotype (with or without aura) are the limitations of these investigations.

To fill in these knowledge gaps, scientists from Brigham and Women’s Hospital in Boston created a significant prospective study to calculate the correlations between pre-pregnancy migraine and the risk of gestational diabetes, gestational hypertension, pre-eclampsia, pre-term delivery, and low birth weight.

The researchers also looked at potential effect modification by aspirin use and examined whether these relationships varied by migraine phenotype in the study, which was published in the journal Neurology.

Study on migraines and pregnancy

Data from the Nurses’ Health Study II (NHSII) were used by Brigham instructors Alexandra Cari Purdue-Smithe, Ph.D., and her team to achieve these goals.

In 1989, 116,430 registered nurses in the United States between the ages of 25 and 42 participated in this study. Questionnaires about participants’ lifestyles and health were given out. Every two years, participants in this study were required to answer questions on their lifestyle and general health.

In 2009, participants submitted information on each pregnancy they had ever had, including any unfavorable results. In 2007, participants in the NHSII were asked if they had ever experienced aura along with their migraine headaches.

Any self-reported medical diagnosis of migraine on the 1989, 1993, and 1995 NHSII questionnaires was considered a migraine for the purposes of this study, according to Purdue-Smithe’s team.

They restricted their studies to 30-555 pregnancies in 19,694 women who had no history of cardiovascular disease, type 2 diabetes, or cancer. These pregnancies had to be at least 20 weeks long.

Using log-binomial and log-Poisson models, the researchers determined the relative risk and 95% confidence interval for each unfavorable pregnancy outcome. These models were adjusted for several confounding variables, including age at conception, age at menstruation’s onset, race and ethnicity, body mass index, chronic hypertension, alcohol use, physical activity, smoking status, analgesic use, oral contraceptive use, infertility diagnosis, and the number of births.

Important results of the migraine study

11% of the 19,694 female participants at baseline had ever been diagnosed with a migraine by a doctor.

According to the statistical studies, migraine was not linked to gestational diabetes or low birth weight, but it was linked to a higher risk of preterm delivery by 17%, gestational hypertension by 28%, and preeclampsia by 40%.

For migraine with and without aura, the risk of preterm birth and the risk of gestational hypertension were comparable. However, compared to women who had migraines without aura, those who had migraines with aura had a slightly increased chance of developing preeclampsia.

The researchers also discovered a 45% decreased risk of preterm birth in migraine-prone women who consistently (more than twice a week) took aspirin before becoming pregnant. Although this particular investigation had limited statistical power, the researchers did find that women who reported regularly taking aspirin before becoming pregnant had a qualitatively decreased risk of preeclampsia.

Understanding pregnancy and migraine

The results are significant, according to Dr. Matthew Robbins, an associate professor of neurology at Weill Cornell Medicine in New York who was not involved in the study.

“We already knew that the relative risk of stroke and overall cardiovascular comorbidity is higher in individuals who have migraine with aura,” he told us. “This is based on large, population-based epidemiological studies.” “Now, we know that this risk may also extend to pregnancy-related complications, such as a higher incidence of pregnancy-specific cardiovascular diseases like gestational hypertension and preeclampsia.”

He continued, “The results of this investigation imply that migraine history and, to a lesser extent, migraine phenotype, are therapeutically helpful predictors of pregnancy risks.

Likewise not taking part in the study was Dr. Sarah E. Vollbracht, an associate professor of neurology at Columbia University in New York.

Given the high prevalence of migraine in women of childbearing age, these findings suggest that migraine screening should be included in initial obstetrical assessments to determine if a woman is at risk of adverse pregnancy outcomes and women with migraine should be closely followed throughout pregnancy and monitored for the development of hypertensive disorders in pregnancy,” she said in a statement to us.

Aspirin use during pregnancy may reduce the risk of preterm birth and preeclampsia, according to the study’s findings, but Vollbracht cautioned that “this finding should be interpreted cautiously” and that “more data, including placebo-controlled studies, is needed to determine the role of aspirin use in pregnant women with migraine.”

Limitations and upcoming studies

The definition of migraine utilized in this study may have understated the actual prevalence of migraine in the study population and, consequently, the relative risks, according to Purdue-Smithe and her co-authors.

Confounding effects from additional factors, such as heredity and drugs specifically designed to treat migraines, cannot be completely ruled out despite the statistical studies taking numerous potential confounding factors into account.

The Nurses’ Health Study II cohort’s limited generalizability is due to the majority of non-Hispanic white study participants.

Future research should focus on including a patient population that is more diverse in terms of racial, cultural, and socioeconomic origins, according to Vollbracht.

She went on to say that “further prospective studies are needed to determine more clearly the difference in risk based on migraine phenotype as well as understanding the influence of attack frequency on the risk of these adverse pregnancy outcomes.”

Additional study is required to better understand how aspirin alters effects, especially in terms of dosage and initiation time.

Future research may need to evaluate the use of daily aspirin during the second and third trimesters as a preventive intervention against preeclampsia for pregnant women with migraine with aura, according to Robbins.

The researchers concluded by saying that further investigation should aim to shed light on the mechanisms behind the connections found in this study.

REFERENCES:

For Migraine medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?therapy=17

More fruits & veggies might reduce death from CKD.

More fruits & veggies might reduce death from CKD.

According to research, eating more fruits and vegetables reduces the chance of death in persons with chronic renal disease.

Doctors may recommend a low-potassium diet to patients with severe chronic kidney disease (CKD) because their kidneys have trouble processing it, resulting in excessive potassium levels in the blood.

In this study, researchers discovered comparable baseline serum potassium levels stratified by CKD stage in various groups based on how frequently they consumed fruits and vegetables.

According to the researchers, this shows that regularly consuming fruits and vegetables may not be linked to a rise in serum potassium levels.

Chronic kidney disease (CKD) patients have a progressive loss of renal function. The National Institute of Diabetes and Digestive and Kidney Diseases estimates that more than one in seven persons in the United States have CKD.

Since there are sometimes no symptoms in the condition’s early stages, CKD frequently stays undiagnosed until it is severe. Sometimes damaged kidneys cause blood levels of potassium to rise. The word for elevated potassium levels is hyperkalemia.

Researchers from one study discovered that more than half of the individuals, all of whom had severe CKD, had potassium levels above the recommended threshold. Occasionally, doctors advise patients with CKD to keep to low-potassium diets as their renal function declines.

Consuming more fruits and vegetables

Officials in charge of public health frequently extol the virtues of eating plants. Consuming fruits and vegetables has been linked to a lower risk of cancer, heart disease, and all-cause death.

According to the researchers, advanced CKD patients occasionally find themselves eating fewer meals that include vegetables and fruits due to worries about maintaining a diet low in potassium.

The 2019 systematic review of observational studies piqued the researchers’ interest because it revealed that hemodialysis patients had poor fruit and vegetable intake and that increasing consumption was linked to a lower risk of all-cause and non-cardiovascular death.

More specifically, the researchers found that consuming roughly 17 servings of vegetables and fruits each week, as opposed to just two, was related to a 20% decreased risk of all-cause mortality.

The researchers chose a Japanese hospital to carry out their study of patients with and without CKD because Asian diets are frequently higher in fruits and vegetables.

Kidney disease diet study

More than 2,000 persons 20 years or older who attended one of the hospital’s several outpatient clinics on Sado Island, Japan, between 2008 and 2016 were a part of this study.

Participants had to provide information about their intake of vegetables and fruits, as well as a record of their baseline serum creatinine and urinalysis measurements. At least one follow-up evaluation was also conducted for them.

The participants’ average age was 69. 64% of the subjects had high blood pressure, 64% were men, and 39% had diabetes.

Participants were divided into groups based on their responses to the question of how often they consume fruits and vegetables: “never or rarely,” “sometimes,” or “every day.” 15% of participants said they never ate fruits and vegetables, while about half said they did so daily.

These participants were separated into three groups: hemodialysis patients, CKD patients, and CKD patients who were not reliant on dialysis. Among the participants, 45% of the patients had CKD but weren’t dependent on dialysis, and 7% were receiving hemodialysis.

With regard to non-dialysis-dependent CKD, more than half of the participants said they regularly ate fruits and vegetables. The percentage of hemodialysis patients who reported eating fruits and vegetables every day was only 28%.

There were 561 fatalities recorded over a median follow-up of 5.7 years. Using obituaries, medical data, and reports from family or friends, researchers were able to determine whether or not the study participants had passed away.

Researchers updated the analyses to account for variables like gender and age, demographics (including individuals’ smoking status and BMI), and a variety of co-morbidities.

Survival benefit of high fruit and vegetable consumption

Those who just occasionally ate fruits and vegetables had a 25% higher chance of passing away from any cause than those who regularly consumed these meals.

A 60% increased chance of passing away from any cause existed for people who either never or infrequently ate fruits and vegetables.

According to initial findings, all CKD stage-strategy groups for vegetable and fruit eating frequency had equal serum potassium levels. This shows, according to the researchers’ article, “that frequency of vegetable and fruit intake is not associated with serum potassium levels even in patients with advanced CKD.”

According to the researchers, “the association was similar regardless of CKD status”, with no effect modification by CKD status.

Our findings imply that daily consumption of fruits and vegetables may not be related with elevated serum potassium levels and that it may actually decrease all-cause mortality in CKD patients, including those receiving [hemodialysis], as opposed to increasing it.

The researchers issued a warning in their publication that participants with severe CKD might have eaten fruits and vegetables that were lower in potassium or soaked or boiled items before eating them to eliminate potassium — a common prescription provided to Japanese CKD patients.

To the contrary, they said, “accumulating evidence suggests that dietary potassium levels are not associated with serum potassium levels or hyperkalemia.”

Kidney disease and potassium

Professor and clinical chief of nephrology at the University of California, Los Angeles’ David Geffen School of Medicine, Dr. Anjay Rastogi, told that the study was “thought-provoking” but that it had certain limitations.

He noted that compared to Americans, a large portion of the population in Japan consumes more fruits and vegetables.

Rastogi was concerned that the individuals would have only submitted labs from one date and had only once reported on their consumption of fruits and vegetables. There were many details that were missing, he claimed.

Rastogi asserted that he believes those with advanced CKD should consume a diet low in potassium. “It’s a very important mineral element in our body, but obviously in patients with kidney disease who have hyperkalemia, it can wreak havoc,” said Dr. Rastogi of potassium. “It might result in cardiac arrest.”

In order to minimise their potassium intake and keep consuming fruits and vegetables, Rastogi advised persons with CKD to engage with a trained dietitian.

There are new potassium binders on the market to treat hyperkalemia for those who cannot control their potassium through diet, he added.

Rastogi declared, “I am a very big advocate of diet and lifestyle changes for slowing down the progression of not just kidney disease but also cardiovascular disease.” Cardiovascular disease is the leading cause of death in patients with kidney disease. Both of them are interrelated.

More complex suggestions

Health professionals frequently “advise people with chronic kidney disease in ways that are not very nuanced,” according to Dr. Deidra Crews, a professor of medicine in the division of nephrology at the Johns Hopkins University School of Medicine in Maryland.

Diets heavy in potassium may be problematic for some people who have very severe chronic renal disease, or even kidney failure, she explained. “However, the vast majority of individuals with chronic kidney disease really have less severe forms of the condition.

Therefore, the majority of the more than 37 million Americans with chronic kidney disease have this type of less severe disease, and the dietary practises that will help them avoid cardiovascular disease and live [a long life] will be very similar to what we might suggest to the more general population, which is: eat your fruits and vegetables.

According to Crews, study into whether diets high in fruits and vegetables are genuinely linked to hyperkalemia in persons with severe CKD is sparked by studies like this one out of Japan.

Even though individuals with advanced CKD frequently cannot eliminate potassium from their bodies through the kidneys, they may be able to do it through “pathways that exist in the gut, in the bowels,” the expert noted.

Crews emphasised that because fruits and vegetables frequently have significant fibre content, they might aid in the process.

REFERENCES:

For Chronic Kidney Disease disease medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?therapy=82

Is Toilet Paper a Source of Cancer-PFAS in Wastewater?

Is Toilet Paper a Source of Cancer-PFAS in Wastewater?

According to researchers, PFAS—also known as potentially dangerous substances—may be released into wastewater systems by using toilet paper. In addition to cosmetics and cleansers, PFAS are also present in paper products.

According to them, a variety of health problems, including cancer, infertility, and liver disease, are thought to be exacerbated by the chemicals. The presence of potentially dangerous compounds known as PFAS in groundwater has been linked to the use of toilet paper.

Cosmetics, cleansers, and firefighting foams are only a few examples of the numerous consumer goods that include per- and polyfluoroalkyl substances (PFAS).

PFAS are suspected of contributing to a number of illnesses, including cancer, lowered immunity, and issues with reproduction and development. However the study is not conclusive in this regard.

What researchers found?

The most frequently found PFAS in sewage sludge samples, while at low levels, was one specific molecule, termed 6:2 diPAP. According to University of Florida researchers who were examining the occurrence of PFAS in wastewater.

Also, samples of toilet paper sold in North America, South America, Africa, and western Europe were found to contain the highest concentration of this PFAS. In the online journal of the American Chemical Society, they today published the results of their research.

In their investigation, the researchers calculated that toilet paper supplied roughly 4% of the 6:2 diPAP in sewage in the United States and Canada. As well as 35% in Sweden and as much as 89% in France.

Jake Thompson, a senior research author and doctoral student at the University of Florida, said that while it isn’t the entire issue, it is undoubtedly a component of it. Data indicate that there are geographical disparities in contamination, he said, adding that.

What are PFAS?

The word “PFAS” describes a family of more than 9,000 different kinds of synthetic compounds. PFAS, which were first discovered in the late 1930s, can still be found in a wide range of items, such as:

  • Carpets and clothing with stain resistance
  • cleaning supplies
  • goods for personal care and cosmetics
  • burning foam
  • a nonstick pan
  • garment that repels water
  • goods that are resistant to water, oil, or grease.

American blood PFAS levels have been tested by the National Health and Nutrition Examination Survey for more than 20 years. According to the survey, the majority of Americans had PFAS in their bloodstreams.

Past studies have connected PFAS exposure to a number of potential health problems, such as:

Where PFAS come from?

According to the study, when turning wood into pulp, certain paper makers inject PFAS. Moreover, fibres from products containing PFAS may be used to make recycled toilet paper.

Timothy Townsend, PhD, a professor of the University of Florida’s Department of Environmental Engineering Sciences and a principal author of the study told, “We believe it comes from the pulping process and is put on instruments to keep paper from adhering.

“PFAS discovered in toilet paper at parts per billion levels are most likely pollutants that emerge from the packaging and/or production process,” concurred Pelch.

According to research, the majority of 6:2 diPAP contamination comes from other consumer products. Due to the comparatively low concentration of 6:2 diPAP in wastewater collected in the United States and the fact that Americans use more toilet paper per capita than individuals in other countries.

It is somewhat misinterpreted, according to Townsend, to think that the landfill or the wastewater treatment facility are the issue.

The health threats from PFAS

According to Craig Butt, PhD, manager of applied markets in the division of Strategic Global Technical Marketing at the biomedical and environmental company SCIEX, a growing body of research studies have demonstrated that PFAS represent serious health and environmental dangers.

According to Butt, PFAS have been linked to a wide range of health issues, including cancer and fertility issues. Also, high cholesterol and liver damage are associated in it. In recent years, regulatory authorities in Europe and the US have started establishing legislative limitations for the presence of PFAS in drinking water and consumer products. There are also no acceptable levels of PFAS exposure for humans, according to recent epidemiological and toxicological studies, meaning that even minute amounts of contamination can have a big impact.

There are 5,000 PFAS compounds, according to Butt, “many of which are not well described or understood.”

Toilet paper and PFAS

Prof. Townsend and his team decided to investigate the possible effects that toilet paper might have on the concentrations of PFAS in wastewater for this study.

While not all studies look for this, he said to MNT, “we recently released a study on PFAS in biosolids, which points to 6:2 diPAP as one of the primary PFAS in wastewater residuals.

“We looked into frequent uses for this chemical, and paper was one of them. That’s why we’re looking at toilet paper,” he said.

Rolls of toilet paper that are sold in North, South, and Central America, Western Europe, and Africa were gathered by researchers. Also, they obtained sewage samples from American wastewater treatment facilities. Scientists discovered that the PFAS type that was most prevalent in both the sewage and paper samples was 6:2 diPAP.

The research group then merged their findings with those from other studies that assessed the concentrations of PFAS in sewage and the usage of toilet paper in various nations.

REFERENCES:

For more details, kindly visit below.

Are the eyes the window to our health condition?

Are the eyes the window to our health condition?

Diabetes, multiple sclerosis, and even Alzheimer’s disease can all be identified simply looking into someone’s eyes. Most people have their eyes checked periodically. However,few may be aware that an eye exam is used for more than simply vision correction and vision testing.

The eye is the only organ in the body that allows for a non-invasive examination of the inside by medical professionals due to its frontal “window.” The retina, which is located at the back of the eye, is where blood vessels and the optic nerve are visible in detail.

An optometrist may refer a patient to a medical ophthalmologist if a normal eye exam causes them to have concerns. The medical ophthalmologist will further investigate by doing additional eye exams. If the results of their examinations point to a systemic disease, doctors can then refer the patient to the appropriate expert.

What can be diagnosed?

A routine eye exam can discover vision issues including nearsightedness, farsightedness, and astigmatism. Also, other eye conditions like glaucoma and age-related macular degeneration. The optometrist can learn a lot about a person’s general health by checking the blood vessels in the retina and the optic nerve.

This non-invasive method can identify a wide range of medical illnesses. This includes hypertension, diabetes, thyroid issues, neurodegenerative diseases like Alzheimer’s and multiple sclerosis, and hypertension that may not be immediately apparent to the eyes (MS).

“Ocular inflammation can damage a variety of eye structures and is frequently the initial symptom of a systemic illness. According to Dr. Ibrahim, concentrated history-taking and a guided evaluation of the pertinent physiological systems, including blood testing, are the keys to determining the cause.

Eye Exams and Your Health

Doctors can identify general health concerns early enough to intervene with the use of eye examinations. With the use of advanced tests, ophthalmologists can more accurately forecast cardiovascular events. This includes stroke and perhaps spot early indications of mental deterioration like Alzheimer’s. Learn how eye exams can reveal much more than simply eye health by reading the information below.

Brain tumours and stroke

Because the blood vessels in the brain and eyes are similar, an eye doctor may occasionally be able to identify a problem with the brain by looking at the blood vessels in the eyes. If swelling or shadows are noticed in the eye, this could be a sign of a dangerous brain problem. This includes a tumour or blood clots that could cause a stroke.

Diabetes

Diabetic Retinopathy (DR) and diabetic macular edoema are conditions where diabetes has damaged the blood vessels in the retina at the back of the eye (DME). In order to help control their blood sugar, the patient would be encouraged to consult a doctor if an optometrist discovered leaky blood vessels in their eyes. The slow changes begin before any visible symptoms are seen. The likelihood of maintaining vision improves with earlier management of diabetic eye illness.

Hypertension

An eye exam can identify high blood pressure, which is characterised by excessive blood vessel pressure. Sometimes even before your regular doctor makes the diagnosis. You can see swelling, haemorrhages, and leakage in the eyes as a result of the blood vessels that are injured. The CDC claims that approximately one in three adults have hypertension, known as “the silent killer,” and that up to 20% of those people are unaware of their condition. Thus, early diagnosis during an eye doctor’s evaluation can actually save lives.

High Cholesterol

Exams of the eyes might also spot cholesterol accumulation. One of the simplest illnesses to diagnose during a thorough eye exam is high cholesterol. Since the deposits of the disease show up on the front of the eye as a thin, grey rim surrounding the cornea. By analysing artery and vein patterns, it can also be found in the retina.

Retinal Blood Vessel Occlusion is a condition in which blockages limit blood flow to the back of the eye. This leads to temporary or permanent vision loss. These deposits may be an indication of the current or future development of this condition.

Heart Problems

Certain heart disorders that cause the carotid artery in the heart to accumulate plaque can also result in deposits that obstruct the ocular arteries in the eyes. An optometrist would often advise consulting a specialist if they notice these modifications to the vascular system at the back of the eye.

Several Sclerosis (MS)

Multiple Sclerosis may be to blame for sudden visual loss (MS). While the colour and appearance of the optic nerve are indicators of MS that the optometrist can detect, such instances will be sent for additional testing to confirm the diagnosis.

Thyroid

There are various ways that thyroid disease can manifest in the eyes. Certain thyroid abnormalities can lead to dry eye illness because the thyroid gland regulates the hormones that influence tear production. Furthermore, hyperthyroidism, an overactive thyroid condition, can cause the extraocular muscles to expand and stiffen, resulting in bulging eyes, a sign of Graves’ disease.

Inflammation

The eyes may become inflamed as a result of systemic illnesses that are linked to inflammation in the body. For instance, uveitis, which can result in eye inflammation, redness, and blurred vision, is more common in patients with autoimmune illnesses including lupus, rheumatoid arthritis, and others.

Cancer

An eye exam can occasionally reveal metastatic malignancies like breast cancer, leukaemia, and other types of cancer. Eye specialists can also diagnose lymphoma and other eye cancers in addition to the previously stated brain cancer, basal cell carcinoma and melanoma (skin cancer), which can also be diagnosed. A good eye check saves lives.

REFERENCES:

  • https://www.medicalnewstoday.com/articles/biking-vs-running-2
  • https://www.brightfocus.org/glaucoma/article/eye-window-your-health
  • https://health.clevelandclinic.org/your-eyes-a-window-to-your-health/
  • https://www.eyecaredoctors.com/2019/12/22/eyes-are-windows-to-your-health-2019/

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Significance of Malignant tissue Tumor and its treatment.

Significance of Malignant tissue Tumor and its treatment.

What is malignant soft tissue tumor?

Malignant soft tissue tumours are uncommon and make up just 1% of all malignancies. These malignant tumours, sometimes referred to as sarcomas, develop in soft connective tissues. Your body’s connecting structures are formed and supported by soft connective tissues as well as bones. Soft tissues consist of:

  • Muscles
  • Ligaments
  • Tendons
  • Cartilage
  • Fat
  • vascular system
  • lymph nodes

Any area of your body might develop malignant soft tissue tumours, although 60% start in the arms and legs. 10% appear in the head and neck, while about 30% start in the torso or abdomen.

Who gets malignant soft tissue tumors?

Malignant soft tissue tumours can develop at practically any age, however they are most prevalent in people between the ages of 50 and 70.

These tumours come in over 50 different varieties. These tumours are typically categorised according to how they developed. Adults are most frequently affected by the following types:

  • Desmoplastic tumours with tiny spherical cells.
  • Stromal tumour of the stomach.
  • Leiomyosarcoma
  • Liposarcoma.
  • malignant tumour of the peripheral nerve sheath.
  • synthetic sarcoma.
  • pleomorphic sarcoma that is not distinguished
  • Angiosarcoma.
  • The Kaposi sarcoma.

What are The Symptoms of Malignant Tumors?

It’s possible that you won’t detect a tumour until it’s too late. Their limbs and legs seem lumpy and unpainful at first, but they can get bigger before becoming painful!

Fatigue, weight loss, and pain are a few of the malignant tumours’ most prevalent symptoms. Malignant tumours can also alter the way the body looks by leaving lumps or bumps on the skin. For treatment, it’s critical to consult a doctor as soon as you have any of these symptoms.

Causes of Malignant Tumors

Malignant tumours can have a wide variety of causes, however it might be difficult to pinpoint a certain tumor’s exact origin. There are, however, a few risk factors that are linked to a higher chance of having a malignant tumour. These include a family history of cancer, exposure to specific chemicals and radiation, and specific chronic health issues.

Even though the precise aetiology of a malignant tumour may not yet be established, awareness-building efforts and the promotion of early detection and treatment can be aided by knowing the possible risk factors. Other typical causes include:

Malignant soft tissue tumors diagnosis

Malignant soft tissue tumours require a number of processes to be diagnosed. Normally, a detailed medical history and physical examination are the first steps taken by healthcare professionals. They might also pass specific exams. Doctors can learn more about the tumour thanks to test results.

These tests could consist of:

  • An X-ray scans the body to look for unusual growths.
  • Using computers, computed tomography (CT) creates cross-sectional images of the inside of your body from a number of X-ray images. This examination is frequently performed to identify cancers in the chest, abdomen, or rear of the abdomen.
  • Using a powerful magnet, radio waves, and a computer, magnetic resonance imaging (MRI) produces detailed images of your body. If an X-ray is abnormal, you might order this to get sharper pictures.
  • Using a particular glucose tracer concentrated in cancer cells, a PET scan can detect the presence of a fast expanding tumour by displaying regions of your body where the level of glucose is higher than normal.
  • Ultrasound: This examination uses sound waves and their echoes to create images of various body parts.
  • A portion of tissue from the afflicted area is removed during a biopsy so that it may be examined under a microscope to look for cancer cells.

Medical treatments

  • Chemotherapy: Patients are administered medications intravenously or orally. In order to reduce tumours that will be removed during surgery or to eradicate any cancer cells that may still be present after surgery, chemotherapy may be utilised as the primary treatment.
  • Radiation: Radiation may be used either before or after surgery to reduce tumour size and eradicate any cancer cells that may have survived.
  • Targeted therapy: In order to alter how cancer cells survive and proliferate, targeted therapy targets particular components of cancer cells, such as genes and proteins.

Surgical procedures

Malignant soft tissue tumours are frequently treated with surgery in an effort to reduce the likelihood that the tumour may come back or spread. In order to remove the tumour completely and preserve as much healthy tissue as possible, surgeons must ensure that no cancer cells are left behind.

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Is there any side effects of using too much Cinnamon?

Is there any side effects of using too much Cinnamon?

What is Cinnamon?

On toast and in lattes, cinnamon is a spice. But for thousands of years, extracts from the cinnamon tree’s bark, leaves, blossoms, fruits, and roots have also been utilised in traditional medicines all throughout the world. It is added to many foods and used in baking and cooking.

The four main types of cinnamon are as follows. The variety of cinnamon that is most frequently offered in the US is cassia, which is darker in colour. Southeast Asia is where it is raised. True cinnamon, commonly referred to as Ceylon cinnamon, is widely utilised abroad.

One of the two primary varieties of cinnamon i.e. Ceylon or Cassia, or a combination of the two—could be the cinnamon you purchase at the shop. Ceylon is easier to grind, but its health benefits might not be as good.

Health Benefits of Cinnamon

Cinnamaldehyde is one of the most significant active components in cinnamon. It is utilised in scents and flavourings. It might be the cause of some of cinnamon’s potential health advantages.

According to certain studies, cinnamon may benefit diabetics. According to a study of 18 studies, cinnamon may help reduce blood sugar levels. Hemoglobin A1C, a marker of blood sugar levels over time, was unaffected, nevertheless. In diabetics, it may also decrease cholesterol.

Numerous studies lack information about the sort of cinnamon they used or have other issues that cast doubt on the accuracy of their conclusions. According to one analysis, cinnamon may aid in reducing obesity and weight gain. Irritable bowel syndrome and other stomach and intestinal issues are occasionally treated with it. But its effectiveness is unclear.

Cinnamon has been proposed to be beneficial for

  • Heart condition
  • Alzheimer’s condition
  • Cancer
  • HIV
  • Infection
  • dental decay
  • Allergies

However, a large number of research have used animal or cell models. Although cinnamon has anti-inflammatory, antibacterial, and antioxidant properties, there are currently insufficient studies to support their effectiveness in treating human conditions.

Side effects of Cinnamon

Cinnamon consumption in moderation is unlikely to have a significant negative influence on your health. Consuming excessive amounts of it is also not recommended.

There is no established dosage for cinnamon because it is an unproven treatment. Some experts advise taking 2-4 grammes of powder, or 1/2 to 1 teaspoon, per day. The amount of cinnamon used in some studies ranged from 1 to 6 grams. High doses could be harmful.

May Cause Liver Damage

A 130-pound (59-kg) person can consume 5 mg of coumarin daily, or approximately 0.05 mg per pound (0.1 mg per kilogramme) of body weight. Accordingly, consuming even a single teaspoon of cassia cinnamon could cause you to exceed the daily limit.

Unfortunately, a number of research have revealed that consuming too much coumarin may harm and poison the liver.

As an illustration, after only one week of taking cinnamon supplements, a 73-year-old woman experienced a sudden liver infection that resulted in liver damage. But in this instance, the dose was larger because of the supplements used than it would be from food alone.

May Increase the Risk of Cancer

An excessive intake of coumarin, which is present in large quantities in Cassia cinnamon, has been linked to an increased risk of some malignancies in animal experiments.

For instance, research on rodents has revealed that consuming too much coumarin might result in the growth of malignant tumours in the lungs, liver, and kidneys. It’s unclear how coumarin might result in tumors.

However, some scientists think that over time, DNA damage brought on by coumarin increases the risk of cancer.

May Cause Mouth Sores

Mouth sores have been reported in certain consumers after consuming items with cinnamon flavouring.

When taken in excessive quantities, the chemical cinnamaldehyde found in cinnamon may cause an allergic reaction. Small doses of the spice don’t appear to trigger this reaction because saliva keeps chemicals from coming into prolonged contact with the mouth.

Other signs of a cinnamaldehyde allergy besides mouth sores include:

  • tongue or gum enlargement
  • a feeling of burning or itching
  • mouth with white spots
  • Although not always serious, some symptoms can nonetheless be uncomfortable.

It’s crucial to remember that cinnamaldehyde only causes mouth sores in people who are allergic to it. A skin patch test can be used to check for this kind of allergy.

May Cause Low Blood Sugar

It is commonly known that cinnamon can reduce blood sugar levels. According to studies, the spice can replicate the actions of the hormone insulin, which aids in removing sugar from the blood.

Although consuming a small amount of cinnamon may help lower blood sugar, doing so excessively may cause it to drop too low. It is known as hypoglycemia. It may cause fatigue, wooziness, and even fainting.

Those who are taking diabetes treatments are particularly at risk of having low blood sugar. This is due to the possibility that cinnamon could intensify the effects of these drugs and cause your blood sugar to drop too low.

May Cause Breathing Problems

This is so that it won’t be difficult to inhale due to the spice’s fine texture. Its accidental inhalation can result in:

  • coughing
  • gagging
  • trying to catch your breath is difficult

Additionally, the cinnamaldehyde in cinnamon irritates the throat. It might result in additional respiratory issues. Being unintentionally exposed to cinnamon should be avoided by those who have asthma or other breathing-related illnesses because they are more prone to have breathing difficulties.

Interact with Certain Medications

With the majority of drugs, cinnamon is safe to consume in small to moderate doses. If you are taking medication for diabetes, heart disease, or liver disease, taking too much may be a problem. This is due to the possibility that cinnamon may interact with such drugs, either amplifying their effects or causing more severe side effects.

For instance, cassia cinnamon has a lot of coumarin, which is poisonous to the liver and might harm it if ingested in large quantities.

A lot of cinnamon may increase your risk of liver damage if you use drugs that could harm your liver, like paracetamol, acetaminophen, and statins.

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What are the causes of Angiosarcoma disease?

What are the causes of Angiosarcoma disease?

A uncommon kind of cancer called angiosarcoma develops in the lining of lymph and blood arteries. The immune system includes the lymphatic vessels. The lymph vessels remove waste materials, viruses, and germs from the body.

Anywhere in the body can develop cancer of this kind. But the skin of the head and neck is where it usually manifests itself. Rarely, it can develop in the skin of other bodily parts, such the breast. Alternately, it might develop in deeper tissues like the liver and heart. Angiosarcoma can develop in locations that have already received radiation therapy.

Symptoms of Angiosarcoma

A skin-related angiosarcoma

Angiosarcoma typically develops in the skin of the head and neck. On the scalp, it often occurs. The following are signs of this type of angiosarcoma:

  • a bump on the skin that resembles a bruise
  • a lesion that resembles a bruise and enlarges over time
  • a wound that could bleed if scratched or jarred
  • Skin around the lesion is swollen.

Organ-specific angiosarcoma

Angiosarcoma frequently results in pain when it affects organs like the liver or heart. The angiosarcoma’s location will affect any additional symptoms.

Causes of angiosarcoma

Most angiosarcomas have unknown origins. Researchers have found a number of variables that could raise the disease’s risk.

Angiosarcoma develops when the DNA of cells lining a blood artery or lymph channel changes. The instructions that inform a cell what to do are encoded in its DNA. The adjustments, which scientists refer to as mutations, instruct the cells to divide quickly. When healthy cells would perish, the alterations prevent the cells from dying.

As a result, cancer cells can accumulate and spread outside of the blood vessel or lymph channel. Cancerous cells are able to infiltrate and obliterate healthy body tissue. Cancer cells could eventually separate and travel to different parts of the body.

Risk elements

The following factors can raise your risk of developing angiosarcoma:

  • Radiation treatment. Angiosarcoma risk may rise after radiation therapy for cancer or other disorders. An uncommon side effect of radiation therapy is angiosarcoma.
  • Swelling brought on by damaged lymph vessels. Lymphedema is swelling brought on by a buildup of lymph fluid. When the lymphatic system becomes obstructed or injured, it occurs. When lymph nodes are removed during surgery, lymphedema can result. This is frequently carried during during cancer surgery. When there is an infection or other disorders, lymphedema can also occur.
  • Chemicals. Exposure to a number of substances has been related to liver angiosarcoma. These substances include arsenic and vinyl chloride, for instance.
  • Inherited syndromes. Angiosarcoma risk can increase in those who are born with specific gene mutations. Examples include the mutations in the BRCA1 and BRCA2 genes that lead to neurofibromatosis, Maffucci syndrome, or Klippel-Trenaunay syndrome.

Genetic disorders linked to Angiosarcoma

Genetic abnormalities that alter genes that are intended to guard you against malignancies have been linked, according to researchers. Conditions specifically include:

  • Two-sided retinoblastoma. The retina in the back of your eyes is where this rare cancer develops.
  • Ollier illness. This uncommon condition affects how your bones grow.
  • Syndrome Maffucci. Your bones’ cartilage is affected by this uncommon condition.

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Benefits and side effects of weight gain capsules.

Benefits and side effects of weight gain capsules.

While many people struggle with weight loss, others battle weight gain. There are good and bad methods to go about improving your strength, developing a more muscular physique, or getting back to a healthy weight after a large weight loss. While not completely risk-free, weight gain supplements and pills may be useful in some circumstances. Focus on eating a healthy diet to gain weight and doing the right kind of exercise to help you reach your goals.

Despite common assumption, not everyone desires eternal thinness, and not everyone puts on weight simply by smelling french fries. Some people find it difficult to gain weight, while others simply like to have well-toned bodies.

Whichever group you belong to, the greatest weight gain pills are the perfect option for you. You can easily reach your optimum weight if you use these appetite suppressants to gain weight.

What are weight gain pills?

Medications recommended by a doctor and over-the-counter supplements both fall under the category of “weight gain medicines.” Despite the fact that over-the-counter goods frequently lack scientific support and are largely unregulated, supplements assert that they encourage safe and natural weight growth.

Consult a healthcare professional to assess the ideal weight range for your health and lifestyle if you’re unsure whether you should aim to gain weight. You should also ask them for guidance about weight-gain supplements. Not everyone should take these supplements.

Prescription Medication for Weight Gain

Anabolic steroids are a component of prescription weight-gain medications. If you have lost a lot of weight and are underweight as a result of a disease like cancer or muscular dystrophy, your doctor could think about prescribing steroids to you.

Bodybuilders and athletes may utilise prescription medicines illegally to bulk up and improve performance. There are numerous health dangers associated with the improper use of anabolic steroids, some of which are very serious. You must only use these medications under a doctor’s supervision.

How Medicines cause weight gain?

Weight gain brought on by medications might have various root reasons. Your appetite may be increased by some medications. You eat more as a result, putting on weight. Your body’s metabolism may be impacted by some medications. Your body burns calories more slowly as a result. You might retain water as a result of some medications. Even if you don’t gain more fat, this causes you to weigh more. The way your body stores and absorbs sugars and other nutrients may be impacted by different medications.

You could be less likely to exercise if a medication makes you feel exhausted or out of breath. Weight gain may result from this. Researchers are unsure of precisely what causes the weight gain when taking some medications.

Drugs that could result in weight gain include:

  • medications for diabetes, including sulfonylureas, thiazolidinediones, and insulin
  • Haloperidol, clozapine, risperidone, olanzapine, quetiapine, and lithium are antipsychotic medications.
  • Amitriptyline, imipramine, paroxetine, escitalopram, citalopram, mirtazapine, and sertraline are examples of antidepressants.
  • medications for epilepsy such as gabapentin, valproate, divalproex, and carbamazepine
  • Prednisone and other steroid hormone drugs, as well as birth control pills
  • medications that lower blood pressure, such as beta-blockers like propranolol and metoprolol

It’s significant to remember that not all of these types of medications result in weight gain. For instance, the diabetes medication metformin may prevent you from gaining weight. Topiramate, a medication for migraines and seizures, can also aid in weight loss.

Symptoms and side effects.

You may have noticed that since starting your medication, you have put on a few pounds. Sometimes, this takes place quickly. Other times, however, it proceeds more gradually. It’s possible that you won’t realise you’ve put on weight until your doctor tells you about it at an appointment.

You can experience other symptoms, depending on the reason for your weight increase. For instance, it can be more difficult for you to exercise or you might have a greater hunger. Even so, you might not always experience these other signs.

Being overweight increases the chance of developing or makes existing health issues worse, including:

  • decreased glucose tolerance or diabetes
  • Arthritis
  • elevated blood pressure
  • Heart condition
  • Stroke
  • Slumber apnea
  • liver illness
  • specific lung diseases
  • Infertility
  • specific cancers
  • psychological difficulties

Your healthcare practitioner will assist you in weighing the benefits and drawbacks of the medicine.

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