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The Risk of Depression May Rise If You Eat French Fries.

The Risk of Depression May Rise If You Eat French Fries.

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According to a recent study, eating fried meals frequently is associated with greater rates of anxiety and sadness.

According to the study, eating fried foods frequently—especially fried potatoes—increases your risk of developing anxiety and depression by 12% and 7%, respectively.

This, according to experts, is due to a number of factors, such as disruption of the lipid metabolism, an increase in inflammation, and gut disruption.

Try boiling, poaching, or grilling your meal as an alternative to frying it to limit your intake of fried foods.

The two mental illnesses that are most common worldwide are anxiety and depression.

Fried foods make up a large portion of the Western diet and are becoming more popular everywhere. Consuming processed or fried foods, sweet goods, and alcoholic beverages have been related to an increased risk of depression, according to prior research.

Additionally, studies suggest that frying may alter the nutritious makeup of food and release toxic compounds. Acrylamide is produced when carbohydrates are fried, such as potatoes, and it has been connected to neurological problems, metabolic syndrome, and obesity.

Few research have looked into how acrylamide might impact anxiety and depression up until this point. Additional research into this connection may help shape public health initiatives and dietary treatments for mental health issues.

Researchers have recently looked into the relationship between eating fried meals and depression and anxiety. They discovered that eating fried food, particularly fried potatoes, is associated with a higher risk of developing anxiety and depression.

How the research was carried out?

The study, which covered 140,728 participants, found that eating regularly unhealthy fried foods increases one’s risk of anxiety and depression by 12% and 7%, respectively.

The pollutant known as acrylamide found in fried foods, according to the researchers, is “strongly associated” with an increased risk of anxiety and depression.

It has been established that this pollutant causes neuroinflammation and perturbs lipid metabolism, both of which have an impact on mental health.

Even though many who enjoy fried food may be disappointed by these findings, there is a positive aspect to them. We may be able to lower our risk of developing some mood disorders by paying closer attention to what we eat.

Examination of the impact of fried food

The researchers started by looking at data from 140,728 individuals in the UK Biobank. During an average follow-up period of 11.3 years, data on fried food consumption and the prevalence of anxiety and depression were collected.

The researchers found 12,735 cases of depression and 8,294 cases of anxiety towards the end of the study period. Overall, they discovered that compared to non-consumers, those who had more than one dish of fried food daily had a 12% higher risk of anxiety and a 7% higher risk of depression.

Males, younger people, and active smokers were most likely to consume fried food frequently. The researchers next looked into potential mechanisms explaining the association between fried foods and depression and anxiety.

They did this by watching how zebrafish were impacted over time by persistent exposure to acrylamide. They discovered that fish exhibited anxiety- and depression-like behaviour when exposed to low amounts of acrylamide.

Following additional tests, the researchers discovered that acrylamide decreased lipid metabolism, caused neuroinflammation, and decreased the blood-brain barrier’s permeability.

Relationship between food and mood

“As opposed to what is frequently portrayed, the relationship between food and mood is far more nuanced. However, there are undoubtedly dietary habits that seem to offer protection, according to Rohini Bajekal, a nutritionist and board-certified specialist in lifestyle medicine at Plant-Based Health Professionals.

“The results of this study are in line with what we would expect to see and are further confirmation of decades of research showing that fried and unhealthy foods in the typical Western diet increase the risk of common chronic diseases and mental health conditions,” says Rohini.

Fried meals contribute to inflammation in the body, which is linked to symptoms of anxiety and depression. This is one of the reasons why fried foods are linked to greater rates of anxiety and depression.

A 2017 study called the SMILES Trial, which Megan Hilbert, a registered dietitian at Top Nutrition Coaching, cites, shows that mental health outcomes were significantly better when a control group adhered to a diet rich in anti-inflammatory foods for 12 weeks.

Inflammation effects on body and brain

Because fried foods contain molecules called advanced glycation end products that stick to tissue, harm it, and promote inflammation, Hilbert claims that a diet high in fried foods contributes to neuroinflammation, or inflammation in the brain.

Although further research is needed on this subject, Hilbert points out that it is hypothesised that inflammation may reduce the release of dopamine and weaken the regions of the brain connected to rewards.

Fried meals also frequently lack fibre, phytonutrients, and healthy fats, all of which have been found to improve brain function. Your digestive system may then be impacted by this.

According to Hilbert, “a deficiency in these compounds can result in a breakdown in the communication between the gut and the brain.” The production of these neurotransmitters is thought to be influenced by abnormalities in our gut microbiota because upwards of 90 to 95% of our serotonin is created there. As a result, it is thought that these imbalances have a negative impact on our mood.

The primary toxin that may be harming mental health, according to the study’s authors, is acrylamide.

Hilbert says that when certain starchy foods are roasted, fried, or baked at high temperatures, a chemical called acrylamide can naturally occur. “Studies have shown that acrylamide is carcinogenic to animals and may be carcinogenic to humans.”

Hilbert emphasises the need of keeping in mind that the acrylamide concentrations utilised in animal experiments were at extremely high dosages.

Foods that promote mental wellness

We discussed whether there are any foods that can help or prevent depression and anxiety with Dr. Kelly Johnson-Arbor, Medical Toxicologist, Co-Medical Director, and Interim Executive Director at the National Capital Poison Centre, who was not involved in the study.

According to Dr. Johnson-Arbor, “There are no specific foods that have been proven to treat or prevent depression or anxiety.” However, compared to the “Western” diet, the Mediterranean diet, which emphasizes the consumption of fruits, vegetables, legumes, and whole grains, is linked to lower levels of C-reactive protein.

Lower levels of C-reactive protein may help prevent the onset of depression, anxiety, and other illnesses impacted by inflammation because they are linked to inflammation, the author continued.

Consequences

We discussed the ramifications of the study with Dr. Spiegel. He stated:

The results of this study suggest that eating more fried food, particularly potatoes, raises the level of acrylamides in the blood. Depression and anxiety may be brought on by the greater levels of this toxin, which affects how different types of nerve cells in the brain function. Among younger people, the effects are more obvious.

The key takeaway is to limit your intake of fried foods like French fries, hash browns, bacon, and others to special occasions. No more than one dish should be consumed per month, in my opinion. Consuming alcohol frequently may increase anxiety and depression as well as cause a number of other health issues, he said.

REFERENCES:

For Depression medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?therapy=6

How metabolic syndrome may increase the risk of Gout?

How metabolic syndrome may increase the risk of Gout?

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Obesity, type 2 diabetes, high cholesterol, and cardiovascular disease all seem to be more common in people with metabolic syndrome(MetS). This may make them more likely to develop in tandem.

The syndrome is a group of risk factors that have been linked to an elevated risk of acquiring additional disorders rather than a single, separate disease.

Metabolic syndrome have a higher risk of developing gout, according to research from the Sungkyunkwan University School of Medicine in South Korea. Its a kind of arthritis that causes pain and swelling in the joints.

A recent study as per the journal Arthritis & Rheumatology, examined over 1.3 million men between the ages of 20 and 39 who had health examinations. The relationship between modifications in the participants’ METs and the onset of gout was examined.

They identified those who had gout using a database of diagnoses. Also, they utilised a statistical model to examine the connection between changes in metabolic syndrome and the onset of gout.

They found that males with metabolic syndrome or those who developed MetS had a higher risk of developing gout. Men who had high triglyceride levels and abdominal obesity—two factors associated with MetS—were at a substantially higher risk.

What is metabolic syndrome (MetS)?

A clinician may suspect metabolic syndrome if a patient displays at least three of the following five signs and symptoms:

  • Specifically, a waist size of more than 40 inches for men and more than 35 inches for women is considered central, visceral, abdominal obesity.
  • 100 mg/dL or more for fasting blood sugar.
  • values of 130/85 mm/Hg or above for blood pressure.
  • Blood triglyceride values of 150 mg/dL or higher.
  • levels of high-density lipoprotein (HDL) cholesterol at or below 50 mg/dL for women and 40 mg/dL or less for men.

What is gout?

An extremely painful, inflammatory, and inflexible form of arthritis known as gout causes the joints to become stiff.

The metatarsophalangeal joint, which is situated at the base of the big toe, is typically affected. An excessive buildup of uric acid in the body is the source of the disorder.

Researchers find

18,473 males in the recent study experienced gout. Compared to people having MetS, people having metabolic syndrome had a nearly four-fold increased risk of developing gout.

The researchers also noted that a participant’s probability of developing gout quadrupled if they had MetS. Yet, the likelihood of developing gout was practically cut in half for those who recovered from MetS.

High triglyceride levels and abdominal obesity were found to have the highest associations with gout risk. This is as per reports of metS factors.

Comparison was made for those in their 20s, 30s, and those who were underweight or had a normal weight. People with underweight were more likely to experience a connection between changes in MetS and gout.

This is the first extensive study to look at the relationship between alterations in the metabolic syndrome and the risk of gout. According to the study, young persons’ chance of developing gout can be greatly decreased by avoiding MetS or recovering from it.

Reports as per studies

Recent epidemiologic studies have revealed that, when compared to controls, those with hyperuricemia and gout had a higher prevalence of the metabolic syndrome.

In a cross-sectional research of 21,544 participants who completed work-related health examinations, those with serum urate levels 9 mg/dL had about a five-fold greater chance of developing metabolic syndrome. This is compared to those with serum urate levels 7 mg/dL.

Ford et al used data from the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2002. They conducted a cross-sectional analysis of 1370 children and adolescents to ascertain the relationship between serum urate and metabolic syndrome.

In the lowest to highest quartiles of serum urate, risk of metabolic syndrome was 1.0%, 3.7%, 10.3%, and 21.1%, respectively. The top quartile of urate had a roughly 15-fold higher risk of metabolic syndrome than the lowest two quartiles.

When comparing data from 1988-1994 to 1999-2006, NHANES also revealed that the prevalence of gout and metabolic syndrome were rising continuously and at comparable rates.

Rashad Barsoum, MD, FRCP, FRCPE, emeritus professor of medicine at Cairo University, and Rheumatology Advisor talked about the epidemiologic link between gout and metabolic syndrome. It is still disputed whether hyperuricemia is a surrogate marker or a confounding risk factor, but the statistical correlation does not suggest causality, he says, despite the significant evidence linking it to the metabolic syndrome.

Action to reduce risks

The findings of this study, according to Mitchell, “should at the very least act as a wake-up call for the children. Diabetes and hypertension are no longer considered “diseases of the elderly.”

“Gout is merely one of the numerous additional hazards that come with these chronic illnesses. In addition to lowering quality of life, early onset of these diseases may also shorten lifespans. This is over the next few decades, according to the expert.

To “promote the findings of this study to the general public and build a gout prevention programme,” Trinh made a number of recommendations, stating that the following actions may be taken:

Make educational materials that describe the connection between MetS and gout, such as pamphlets, posters, and infographics. Also, the information in these materials must to cover lifestyle modifications for managing MetS.

Join up with medical professionals including primary care doctors and endocrinologists to promote gout prevention strategies and share information about the study’s findings.

Use social media: Share information about the study’s findings and encourage healthy lifestyle choices. By using social media sites like Facebook, Twitter, and Instagram, this can be done.

To inform those who have MetS about the connection between the condition and gout and to offer advice on how to treat it with lifestyle changes, hold workshops or webinars for them.

To promote gout prevention practises to a larger audience, work with neighbourhood organisations like wellness centres or municipal health agencies.

REFERENCES:

  • https://www.medicalnewstoday.com/articles/gout-combining-2-existing-drugs-doubles-treatment-success-in-new-study
  • https://www.rheumatologynetwork.com/view/rheumatoid-arthritis-year-in-review-2022
  • https://www.rheumatologyadvisor.com/home/topics/gout/examining-the-connection-between-gout-and-metabolic-syndrome/
  • https://rheumatology.medicinematters.com/gout/cardiovascular-disease/metabolic-syndrome-gout-risk/23767656

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What’s the relation between Metabolic syndrome and ED?

What’s the relation between Metabolic syndrome and ED?

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Summary

Erectile dysfunction (ED) is characterized by an inability to maintain an erection sufficient for a satisfactory sexual encounter. The metabolic syndrome is a constellation of symptoms that increases the risk of heart disease in patients. Studies have linked the metabolic syndrome to ED.

The presence of ED is an important indicator that a patient may be at risk for a cardiovascular event within five years of onset. In the same way, metabolic syndrome has multifactorial causes, so it may also have multifactorial effects on erectile function. The purpose of this blog is to review on how metabolic syndrome and its components are associated with ED. Also, whether interventions targeted at improving metabolic syndrome components can improve the condition.  

Introduction

A man with erectile dysfunction (ED) is unable to achieve and/or maintain an erection sufficient for satisfactory sexual performance. ED is the most commonly treated sexual dysfunction in men worldwide. It is found in 15% of men between 40 and 50 years old. Also in 45% of men between 60 and 70 years old, and 70% of older men.

The association between ED and cardiovascular disease (CVD) has been documented for the past decade. It may be difficult to establish causality, but ED appears to be an indicator of systemic disease, with both ED and CVD arising from the same cause.

What is Erectile dysfunction?

Erectile dysfunction is basically a disorder found in men which could be a sign of physical or psychological condition. The symptoms associated with this disorder is found in men’s reproductive organ i.e. inability to keep an erection firmer and longer enough during a sexual activity.

There are many men who experience erectile dysfunction occasionally because of stress, fatigue, alcohol, or emotional issues, but 25% of men have recurring episodes of the disorder. People dealing with erectile dysfunction will be:

  • Unable to achieve erection at anytime needed.
  • might achieve erection sometime but not when needed like during sexual activity.
  • might able to achieve erection when needed but not long enough

What is Metabolic Syndrome?

A metabolic syndrome is a collection of conditions that occur together, increasing your risk of type 2 diabetes, heart disease, and stroke. A number of conditions are associated with obesity, including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.

The presence of just one of these conditions does not necessarily indicate metabolic syndrome. It does, however, increase your risk of serious diseases. In addition, if you develop more of these conditions, you face a greater risk of complications, such as type 2 diabetes and heart disease.

Link between ED and Metabolic syndrome

Metabolic syndrome has attracted considerable attention as a result of its increasing association with various pathophysiologic conditions, including heart failure, type 2 diabetes, and erectile dysfunction. It has been shown in numerous studies that various components of the Metabolic syndrome are directly correlated with ED.

Additionally, an independent association between components of Metabolic syndrome and ED was found in the study. Kupelian et al. showed that even at a BMI of 25, Metabolic syndrome is associated with an increased ED risk (relative risk = 2.09) using data from the Massachusetts Male Aging Study.

An analysis of adult participants in the 2001–2004 National Health and Nutrition Examination Survey revealed an association between poor glycemic control, impaired insulin sensitivity, and the Metabolic syndrome and an increased risk of ED.

Conclusion:

To prevent or control the epidemic trend of the Metabolic syndrome and its consequences, strategies must be developed. Identification and treatment of at-risk individuals early could aid in the improvement of ED and secondary cardiovascular disease, such as weight management, lifestyle changes, and physical activity. There have been several studies that have demonstrated the effectiveness of the intervention. In a recent study, Esposito et al. found that a Mediterranean-style diet is beneficial in reducing the prevalence of ED in men with Metabolic syndrome, as it is rich in whole grain, fruits, vegetables, legumes, walnuts, and olive oil.

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