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8 Best Prenatal Vitamins of 2025: A Complete Pregnancy Nutrition Guide

8 Best Prenatal Vitamins of 2025: A Complete Pregnancy Nutrition Guide

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Explore the 8 best prenatal vitamins of 2025 to support a healthy pregnancy. Learn benefits, ingredients, safety tips, and expert recommendations.

Pregnancy is a crucial phase in a woman’s life, and proper nutrition plays a key role in the healthy development of the baby. Even with a balanced diet, many essential nutrients may still fall short. This is why prenatal vitamins are highly recommended by doctors worldwide.

In this article, we cover the 8 best prenatal vitamins of 2025, selected based on nutrient quality, safety, effectiveness, and suitability for expecting mothers.

Why Prenatal Vitamins Are Important During Pregnancy

Prenatal vitamins provide essential nutrients that support both maternal health and fetal development. These supplements help reduce nutritional gaps and lower the risk of pregnancy-related complications.

  • Support the baby’s brain and spinal cord development
  • Reduce the risk of birth defects
  • Prevent pregnancy-related anemia
  • Strengthen bones and teeth
  • Support immune health

Key nutrients include folic acid, iron, calcium, vitamin D, iodine, DHA, and vitamin B12.

8 Best Prenatal Vitamins of 2025

1. Nature Made Prenatal Multi + DHA

This doctor-recommended prenatal vitamin contains folic acid, iron, and DHA to support fetal brain development and maternal energy levels.

  • Supports baby’s brain growth
  • Reduces neural tube defects
  • Improves blood health

2. Garden of Life MyKind Organics Prenatal

An organic, whole-food prenatal vitamin made from plant-based ingredients. Ideal for women seeking natural pregnancy supplements.

  • Certified organic formula
  • Gentle on digestion
  • Supports immune function

3. One A Day Women’s Prenatal Advanced

This advanced prenatal formula offers essential vitamins and minerals along with DHA for eye and brain development.

  • Supports fetal eye health
  • Boosts immunity
  • Easy once-daily intake

4. Rainbow Light Prenatal One Multivitamin

Specially formulated for women with sensitive stomachs, this prenatal vitamin contains digestive enzymes and probiotics.

  • Easy to digest
  • Improves nutrient absorption
  • Helps reduce nausea

5. MegaFood Baby & Me 2 Prenatal Vitamins

Made with real food ingredients, this prenatal vitamin supports pregnancy and breastfeeding nutrition.

  • Non-GMO formula
  • Supports iron absorption
  • Promotes healthy energy levels

6. Ritual Essential Prenatal

A clean-label prenatal vitamin containing only essential nutrients without unnecessary additives.

  • No artificial colors or preservatives
  • Supports long-term maternal health
  • High ingredient transparency

7. SmartyPants Prenatal Formula Gummies

A chewable prenatal vitamin option for women who struggle with swallowing tablets.

  • Easy and tasty to consume
  • Contains DHA and folate
  • High bioavailability

8. New Chapter Perfect Prenatal Multivitamin

This fermented whole-food prenatal vitamin supports digestion, immunity, and sustained energy.

  • Supports gut health
  • Improves nutrient absorption
  • Boosts maternal vitality

How to Choose the Right Prenatal Vitamin

When selecting a prenatal vitamin, always consider:

  • Doctor’s recommendation
  • At least 400–800 mcg of folic acid
  • Iron content for anemia prevention
  • DHA for the baby’s brain development
  • Calcium and vitamin D for bone strength

You can explore trusted vitamins and supplements from our pharmacy for pregnancy care.

Safety Tips for Prenatal Vitamins

  • Consult your doctor before starting any supplement
  • Do not exceed the recommended dosage
  • Avoid combining multiple multivitamins
  • Store supplements in a cool, dry place
  • Check expiry dates regularly

Conclusion

The 8 best prenatal vitamins of 2025 listed above provide essential nutrients that support a healthy pregnancy and safe fetal development. Choosing the right prenatal supplement can help reduce pregnancy risks and ensure optimal nutrition for both mother and baby.

For authentic prenatal vitamins and pregnancy supplements, trust MyGeneric Pharmacy for quality, safety, and affordability.

7 Best Multivitamins for Men Over 50 in 2025, According to Dietitians

7 Best Multivitamins for Men Over 50 in 2025, According to Dietitians

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For older adults, it can be harder to get the nutrients they need through food alone. These multivitamins for men may help. Nutritional requirements can vary depending on factors such as your age, sex, and health, so not all multivitamins may be a good fit for everyone.

Chronic health conditions, nutrient absorption, and body composition can change as you age. As a result, men over 50 may benefit from a multivitamin tailored to their needs.

To help you decide which product is right for you, we rounded up the seven best multivitamins for men over 50, according to registered dietitians.

How We Chose the Best Multivitamins for Men Over 50

  • Expert recommendation: The supplements below were selected and reviewed by registered dietitians
  • Ingredients: We selected multivitamins made with high-quality ingredients and free from unnecessary additives and fillers
  • Nutritional value: We focused on products containing nutrients essential for healthy aging in men , including highly absorbable nutrient forms.
  • Quality testing: Preference was given to supplements that undergo third-party quality testing for purity and potency.

Men’s Nutrients Multivitamin

Designed for adults aged 40 years and older, Men’s Nutrients is an excellent choice for those seeking a high-quality multivitamin to support healthy aging.

In addition to micronutrients that promote bone health , such as calcium and vitamin D, it includes blends that support endurance as well as prostate, heart , and eye health .

It is also rich in vitamin B12, which can be harder to absorb with age.

Men’s Nutrients is non-GMO, vegetarian-friendly, and free from common allergens such as dairy and soy. It is also certified gluten-free. All products are tested in accredited laboratories and audited by NSF International.

Nature Made Multivitamin for Men. 50+

This once-daily multivitamin from Nature Made provides 22 key nutrients to support overall health in men over 50.

It is certified by the United States Pharmacopeia (USP) and is one of the most budget-friendly options available.


However, it contains vitamin K, which may interact with
blood-thinning medications such as warfarin. Always consult your healthcare provider before

Reference:
https://www.healthline.com/nutrition/best-multivitamin-for-men-over-50#our-picks

Medications that have been suggested by doctors worldwide are available on the link below
https://mygenericpharmacy.com/category/products/disease/vitamins-enzymes

8 Best Prenatal Vitamins of 2025:

8 Best Prenatal Vitamins of 2025:

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Our dietitians analyzed the ingredients, our medical vetting team evaluated the brands’ reputations and health claims, and our editors provided feedback on their experiences taking these prenatal vitamins. And the results are in. Whether you’re looking for a pregnancy vitamin that will stay put when morning sickness hits, or you want something to take before you get pregnant, these are eight options worth considering.

The prenatal supplements on our list were purchased independently or by mygenericpharmacy. Furthermore, our opinions are our own and have not been reviewed, approved, or endorsed by the supplement manufacturers.

We chose Perelel as the best trimester-specific prenatal because it’s a subscription service that offers supplements tailored to your pregnancy trimester. For example, the First Trimester Prenatal Support Pack contains extra folate, as well as added vitamin B6 and ginger to reduce nausea. These prenatals also contain iron, which can lead to constipation for some who already eat plenty of iron in their diet through food. An OB-GYN founded the company, and each product is free of artificial additives and third-party tested for accuracy and purity.

The First Trimester pack includes 5 capsules, which may be difficult to tolerate if you have morning sickness. However, the company also released a powdered form of its First Trimester Pack as an alternative that may be easier for some people to tolerate. Our first tester had a positive experience throughout her second pregnancy, without any fishy burps from the EPA and DHA. As a dietitian, she appreciated that the brand uses high-quality ingredients in the best forms. She also found the packs really convenient for travel.

Another reviewer (who preferred Thorne’s prenatal) noted a couple of downsides: She found the smell to be really potent. She also felt a little wasteful when she wound up with some leftover product when it was time to switch to the next trimester pack.

Tester Catherine Conelly took Ritual in 2022 during her first pregnancy, choosing it because of the traceable ingredients. She didn’t experience issues with taste or nausea, but did occasionally get the fishy burps despite the capsule’s unique design to help prevent this. Overall, I found the vitamin’s taste and smell to be quite neutral, she said. To round out my daily routine, I also took Ritual’s Essential Protein Daily Shake, Pregnancy & Postpartum for the extra choline. I try to eat a mostly plant-based diet, so I chose this powder because it provides a complete amino acid profile along with an extra boost of choline for pregnancy.

Catherine ultimately switched to FullWell (also featured on our list) toward the end of her pregnancy and throughout breastfeeding. She did this to make sure she was getting a more comprehensive nutrient profile as she was navigating life as a new mom, and not taking as much care to plan balanced meals.

Complete your prenatal product routine.
Even the best prenatal vitamins often lack certain nutrients, such as choline, omega-3s, or iron. Therefore, it may be best to consider purchasing additional supplements as needed to fill in any gaps in your diet that your prenatal vitamin doesn’t cover.

Here are some supplements that may be helpful:
FullWell Iron Bump: For people needing additional iron, FullWell Iron Bump provides 25 mg of easily absorbable iron that’s gentle on the digestive tract.
Ritual Natal Choline: With 550 mg of choline, you might consider using this supplement alongside the brand’s prenatal and postnatal supplements to provide more than 100% of recommended choline needs during pregnancy and breastfeeding.
Ritual Essential Protein Daily Shake Pregnancy & Postpartum: In addition to 20 g of protein per serving, this protein powder also provides choline, calcium, and iron to support nutrient needs during pregnancy and breastfeeding.
Needed Vitamin D: This supplement provides 50 mcg of vitamin D in one capsule and comes in a small size to make it easier to take.

Reference:
https://fortune.com/article/best-prenatal-vitamins/
https://www.thebump.com/a/best-prenatal-vitamins
https://www.healthline.com/health/pregnancy/best-prenatal-vitamins

Medications that have been suggested by doctors worldwide are available on the link below:
https://mygenericpharmacy.com/category/products/disease/vitamins-enzymes

Most People Aren’t Getting Enough Omega-3: What Are the Health Impacts?

Most People Aren’t Getting Enough Omega-3: What Are the Health Impacts?

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A new research review reports that most people do not consume the recommended amounts of omega-3 fatty acids. These acids are considered beneficial for brain, skin, and heart health.
Experts say a person should obtain omega-3s through foods, but supplements can be considered if a person’s diet doesn’t contain enough fatty acids.
The majority of people worldwide are not consuming a sufficient amount of omega-3 fatty acids, according to new research.

Researchers report that 76% of the global population is not consuming the daily recommended levels of omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They said the health benefits from these fatty acids are “too important to ignore. They recommend that health officials develop official policies on omega-3 consumption and advise the public on how to best obtain these fatty acids through diet, as well as through supplements such as fish oil.

We hope this work will help inform nutritional scientists, clinicians, food and supplement industries, policy makers, and consumer communities, said Anne-Marie Minihane. The researchers emphasized that the health benefits of omega-3 fatty acids are important at every stage of life, particularly for pregnant individuals, infants, and young children.

The researchers reached their conclusions after reviewing the recommended daily levels of omega-3 fatty acids in over 100 countries. They noted that the recommendations vary significantly from country to country, creating confusion among the public and highlighting the importance of consistent, evidence-based guidance. They reported that the most frequently recommended intake for adults is 250 mg per day of combined EPA and DHA, with an additional 100 to 200 mg of DHA advised for pregnant people.

They said these levels can be achieved by eating more oily fish, such as salmon or mackerel, or through supplementation where needed. The researchers recently shared their findings in Nutrition Research Reviews, a publication of Cambridge University Press. The authors also acknowledged they have ties to companies such as Holland & Barrett that are involved in the supplement industry. Experts not involved in the research said the review sheds light on an important issue.

It highlights the inconsistencies in how much fatty acid intake is necessary,” said Cheng-Han Chen, MD, an interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA.

The overall message is clear that people should incorporate fatty acids in their diet, It’s a good overview of some of the challenges with getting enough omega 3s through diet alone as well as a look into how various age groups are doing with getting enough omega 3s, recommendations for amount, and unique deficiency risk factors based on age, added Kristin Kirkpatrick, RD, the president of KAK Consulting as well as a dietitian at the Cleveland Clinic Department of Wellness & Preventive Medicine in Ohio.

Health benefits from omega-3 fatty acids
Omega-3s are a family of essential fatty acids. In addition to EPA and DHA types, there is also alpha-linolenic acid (ALA). These acids are not produced by the human body, so they must be absorbed through diet or supplementation.

David Cutler, MD, Santa Monica, California, explains that fats, such as omega-3s, are important because they help our bodies absorb other fat-soluble nutrients, including vitamins A, E, D, and K. Cutler wasn’t involved in the new review. Omega-3s, in particular the DHA type, are considered essential for brain, skin, and eye health. Research has been mixed on what other health benefits are provided by adequate levels of omega-3 fatty acids.

However, past research has reported that these fatty acids can improve heart health by lowering triglyceride levels and increasing HDL, or “good cholesterol,” levels. The benefits of these omega-3 fatty acids are mostly attributed to lowering triglyceride levels in the bloodstream,” Cut. “This is important if you have abnormally high triglycerides and probably not so important if your triglyceride levels are normal.

There has been other research that reported that omega-3 fatty acids may help improve blood sugar levels and lower inflammation. Experts say omega-3s are particularly important for pregnant and nursing women as these fatty acids are vital for the brain health of fetuses as well as infants. Fatty acids are important, Chen said. In particular, they’re important for infant health. In pregnancy, omega-3 deficiency may have an impact on the overall cognitive and neurological health of the baby,” added Kilpatrick.

Omega-3s may be more important for older adults simply because they are at higher risk of some of the health problems that fatty acids can help prevent. They’re susceptible to the same issues as people with omega-3 deficiencies, he said. Some symptoms indicate a low level of omega-3 fatty acids in the body. They include:

skin irritation and dryness
dry eyes
joint pain
changes in hair texture

The American Heart Association (AHA) recommends two servings of fatty fish per week. Those who are unable to consume sufficient omega-3 acids through their diet may wish to consider omega-3 supplements that include fish oil and algal oil.

Cutler offered a word of caution about fish oil capsules. He noted that supplements are not regulated by government agencies like medications and other products. He also said there can be side effects such as nausea and diarrhea.

Additionally, fish oil supplements may increase the risk of bleeding. He noted that it’s particularly important for anyone taking blood-thinning medications. Any benefits to omega-3 supplements should be weighed against potential side effects and risks.

Chen doesn’t generally recommend supplements to boost omega-3 counts. He says the research doesn’t support the notion that supplements effectively boost fatty acid levels. In general, the recommendation is to get fatty acids through diet,” Chen said. “All supplements affect is your wallet.

Reference:
https://www.healthline.com/health-news/omega-3-deficiency-health-impacts#How-to-know-if-you-re-getting-enough-omega-3

Medications that have been suggested by doctors worldwide are available on the link below
https://mygenericpharmacy.com/category/disease/vitamins-enzymes

What to eat and drink before and after a flu shot

What to eat and drink before and after a flu shot

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During the Flu: The Most Critical Phase

When you are actively sick, your appetite will likely be low. The primary focus should be on hydration and getting calories in whatever form you can tolerate.

What to DRINK (Hydration is Key):

  • Water: Essential. Sip consistently throughout the day.
  • Electrolyte Solutions: Pedialyte, Liquid IV, or even diluted sports drinks can help replenish sodium, potassium, and other electrolytes lost through sweat and fever.
  • Broth and Bone Broth: Savory, hydrating, and provides electrolytes like sodium. Bone broth adds the benefit of collagen and some protein, which can be soothing and supportive.
  • Herbal Teas: Ginger tea (settles nausea), peppermint tea (clears sinuses, soothes stomach), or chamomile tea (promotes rest). Add honey and lemon for extra soothing properties and a calorie boost.
  • Diluted Juice: Mix 50/50 with water to provide some sugar for energy without overloading your system.

What to EAT (When You Can):

Focus on the “BRAT” diet if your stomach is upset, but don’t stay on it long-term.

  • Bananas: Easy to digest, provide potassium, and provide energy.
  • Rice (White): Plain white rice is bland and binding, which can help with diarrhea.
  • Applesauce: Provides pectin, which can help with diarrhea, and easy calories.
  • Toast (White): Plain, dry toast is easy on the stomach.
  • Other Good Options:
    • Plain Crackers or Pretzels
    • Boiled Potatoes (without butter)
    • Plain Oatmeal or Cream of Wheat
    • Chicken Noodle Soup: The classic for a reason—it provides fluids, electrolytes, and easy-to-digest protein and carbs.

🍎 After the Flu: The Recovery Phase

Once your appetite returns and symptoms subside, your body needs to rebuild and repair. Focus on nutrient-dense foods.

What to DRINK (Continue Replenishing):

  • Water: Keep hydration a priority.
  • Smoothies: An excellent way to pack nutrients. Blend greens (spinach), fruit (berries, banana), protein (Greek yogurt, protein powder), and a healthy fat (avocado, chia seeds).
  • Milk or Fortified Plant-Based Milks: Provides protein, calories, and nutrients like Vitamin D.

What to EAT (Nutrient-Dense Foods):

Prioritize protein, healthy fats, and colorful fruits and vegetables to replenish vitamin and mineral stores.

  • Lean Protein: Your body uses protein to repair tissues and make new immune cells.
    • Examples: Grilled chicken, fish (like salmon, which also has anti-inflammatory omega-3s), eggs, tofu, and lentils.
  • Fruits and Vegetables: To restock on vitamins, minerals, and antioxidants.
    • Examples: Citrus fruits (Vitamin C), berries (antioxidants), leafy greens (iron, folate), and sweet potatoes (Vitamin A, beta-carotene).
  • Probiotics: To replenish the healthy gut bacteria that can be disrupted by illness.
    • Examples: Yogurt, kefir, kimchi, sauerkraut, and kombucha.
  • Healthy Fats and Complex Carbs: For sustained energy.
    • Examples: Avocado, nuts, seeds, whole-grain bread, brown rice, and quinoa.

🛡️ Before the Flu: The Prevention Phase

A strong, well-nourished body is better equipped to fight off viruses. There’s no single “magic” food, but a consistent, balanced diet is your best defense.

What to EAT & DRINK for a Resilient Immune System:

  • Colorful Fruits & Vegetables: Aim for a “rainbow” to get a wide array of vitamins and antioxidants.
  • Lean Proteins: Essential for building immune cells. Zinc, found in seafood, poultry, beans, and nuts, is particularly important for immune function.
  • Vitamin C-Rich Foods: Supports various cellular functions of the immune system.
    • Examples: Citrus fruits, bell peppers, strawberries, and broccoli.
  • Vitamin D Sources: Crucial for immune health.
    • Examples: Fatty fish (salmon, tuna), fortified milk, and eggs. Sunlight is the primary source.
  • Stay Hydrated: Proper hydration is essential for all bodily functions, including the circulation of immune cells.

✅ Quick Summary Table

PhasePriorityTop Food & Drink Choices
Before (Prevention)Immune SupportColorful fruits & veggies, lean protein, citrus, nuts, seeds, plenty of water.
During (Illness)Hydration & Easy CaloriesBroth, electrolyte drinks, herbal tea, bananas, toast, applesauce, plain rice, crackers.
After (Recovery)Rebuilding & ReplenishingLean protein (chicken, fish, eggs), probiotics (yogurt), fruits & vegetables, whole grains, smoothies.

Listen to Your Body: This is the most important rule. If you’re not hungry, don’t force yourself to eat. Focus on fluids. As your appetite returns, start with bland, easy foods and gradually work your way back to your normal, healthy diet. If you have specific health conditions or severe symptoms, always consult a doctor or a registered dietitian.

Reference:
https://www.medicalnewstoday.com/articles/what-eat-drink-before-after-flu-shot-vaccine-questions
https://jacksonhealth.org/what-to-eat-or-drink-after-getting-the-flu-shot/
https://www.eatingwell.com/what-to-eat-and-drink-before-and-after-the-flu-shot-11815468
https://www.adventisthealth.org/blog/what-to-do-before-and-after-your-flu-shot

Medications that have been suggested by doctors worldwide are available on the link below
https://mygenericpharmacy.com/category/products/disease/vitamins-enzymes

Pee-Less Multivitamins: Can Supplements Really Reduce Frequent Urination?

Pee-Less Multivitamins: Can Supplements Really Reduce Frequent Urination?

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Frequent urination can be uncomfortable, embarrassing, and disruptive to daily life. While doctors usually check for medical causes first, many people also look for natural solutions to support bladder control. This is where “pee-less multivitamins” or bladder-support supplements come in. These products are not typical multivitamins; they contain a blend of vitamins, minerals, and herbal ingredients that support bladder strength, reduce urgency, and help you pee less frequently.
In this blog, we explore how these supplements work, their key ingredients, and the best options available in India.

What Are Pee-Less Multivitamins?

“Pee-less multivitamins” are supplements designed to support:
Bladder muscle strength
Urinary control
Reduced frequency and urgency
Better nighttime bladder function (less waking up to pee)
They are not a replacement for medical treatment but may help people with overactive bladder, mild incontinence, weak bladder muscles, or post-aging urinary issues.
How Do Pee-Less Multivitamins Work?

These supplements work through a combination of:
✔️ Bladder muscle support

Ingredients like pumpkin seed extract strengthen the pelvic and bladder muscles.
✔️ Hormonal & tissue support

Soy isoflavones and magnesium help improve bladder elasticity and reduce irritation.
✔️ Anti-inflammatory action

Many herbal ingredients calm bladder inflammation.
✔️ Urinary tract cleansing

Cranberry and D-mannose help reduce irritation caused by bacteria.
Key Ingredients Found in Pee-Less Multivitamins
Most bladder-support multivitamins contain scientifically studied ingredients:

  1. Pumpkin Seed Extract
    One of the most powerful natural ingredients for bladder control.
    Helps reduce:
    Frequent urination
    Nighttime urination
    Urine leakage
  2. Soy Isoflavones
    Supports bladder lining and muscle tone, especially effective for women.
  3. Magnesium
    Calms bladder muscle spasms and reduces urgency.
  4. Cranberry Extract
    Helps maintain a clean and healthy urinary tract.
  5. Vitamin D
    Low Vitamin D is linked to higher urgency and incontinence.
  6. D-Mannose
    Helps flush bacteria and supports urinary tract health.
    Best Pee-Less / Bladder-Support Multivitamins Available in India
    Here are popular and effective options you can find in India or get delivered easily:
  7. Vestige U-Control
    Indian product
    Pumpkin seed + soy isoflavones
    Supports bladder control and reduces leakage
  8. Urenin Urine Incontinence Capsules
    Contains vitamins + minerals + bladder herbs
    Helps reduce urgency and frequency
  9. Pumpkin Seed Extract Supplements (Inlife, Vedagen, etc.)
    Pure and effective
    Strengthens bladder muscles
  10. Happee Bladder Control (Imported)
    Pumpkin seed + soy + saw palmetto + cranberry
    4-in-1 advanced bladder support
  11. Bladdergenix (with Urox Blend)
    Clinically studied formula
    Reduces urgency and nighttime peeing
    Who Should Consider Pee-Less Multivitamins?
    These supplements may help people who experience:
    Frequent urination
    Urgency to urinate
    Weak bladder control
    Stress incontinence (leakage when coughing/laughing)
    Age-related bladder weakness
    Nighttime urination (nocturia)
    If symptoms are new, sudden, or severe, always consult a doctor first.

Benefits of Pee-Less Multivitamins
✔️ Reduce frequency of urination
✔️ Strengthen bladder muscles
✔️ Reduce leakage and urgency
✔️ Improve sleep by reducing nighttime trips to the bathroom
✔️ Support urinary tract health
✔️ Natural and safe when used properly

Do They Really Work?
Pee-less multivitamins are supportive, not miracle cures.
They work best when:
Taken consistently
Combined with pelvic floor exercises
Paired with reduced caffeine and alcohol intake
Medical conditions are ruled out
Most people notice improvements in 3–8 weeks.

Safety & Precautions
Not for pregnant or breastfeeding women unless the doctor approves
People with prostate enlargement, diabetes, and kidney issues should consult a doctor
Supplements should not replace medical treatment for UTIs
Choose reputable brands only

Final Thoughts
Pee-less multivitamins are becoming a popular natural option for managing bladder issues. While not a replacement for medical care, they can help reduce frequent urination, strengthen bladder muscles, and improve overall urinary health.
If you struggle with urgency, leakage, or nighttime urination, adding a high-quality bladder-support multivitamin to your routine may offer real relief.

Reference:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3085565/
https://nafc.org/bhealth-blog/3-vitamins-that-may-help-with-bladder-control/
https://www.medicalnewstoday.com/articles/supplements-for-overactive-bladder

Medications that have been suggested by doctors worldwide are available on the link below
https://mygenericpharmacy.com/category/products/disease/vitamins-enzymes

3 ways vitamin D may boost longevity, according to research

3 ways vitamin D may boost longevity, according to research

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While the direct link between vitamin D supplementation and increased lifespan is still an active area of research, studies consistently show strong associations between adequate vitamin D levels and a lower risk of diseases that are major drivers of mortality.

Here are 3 ways vitamin D may boost longevity, according to research:

1. By Slowing Cellular Aging: Protecting Your Telomeres

One of the most fascinating theories connecting vitamin D to longevity involves its effect on telomeres.

  • What are Telomeres? Think of telomeres as the protective plastic caps at the ends of your shoelaces (your chromosomes). Each time a cell divides, these telomeres get slightly shorter. When they become too short, the cell can no longer divide and becomes senescent (aged) or dies. Shorter telomere length is a hallmark of biological aging and is linked to a higher risk of age-related diseases and earlier death.
  • Vitamin D’s Role: Research has found that people with higher vitamin D levels tend to have longer telomeres.
  • The Mechanism: Vitamin D has potent anti-inflammatory and antioxidant properties. Chronic inflammation and oxidative stress are two major forces that accelerate telomere shortening. By mitigating this damage, vitamin D may help preserve telomere length, effectively slowing the cellular aging process and promoting longer healthspan.

The Bottom Line: By protecting your telomeres from premature shortening, vitamin D may help you age more slowly at a cellular level.

2. By Fortifying Your Defenses: Reducing the Risk of Major Diseases

Vitamin D’s most well-established role is in regulating calcium for bone health, but its influence extends to nearly every system in the body. Adequate levels are linked to a significantly lower risk of the leading causes of death.

  • Cardiovascular Health: Vitamin D helps regulate blood pressure, reduce arterial stiffness, and control inflammation in the blood vessels. Numerous observational studies have found that vitamin D deficiency is associated with a higher risk of heart attack, stroke, and heart failure.
  • Cancer Prevention: Research, including a large meta-analysis published in the BMJ, suggests that maintaining adequate vitamin D levels may lower the overall risk of cancer, particularly colorectal cancer. Vitamin D is believed to play a role in cell differentiation, slowing the proliferation of cancerous cells, and promoting their self-destruction (apoptosis).
  • Immune Function & Infection: Vitamin D is crucial for activating the immune system’s defenses. It helps your body produce proteins that fight off bacteria and viruses. Studies have shown that adequate vitamin D levels can reduce the risk of acute respiratory infections, which are a significant cause of mortality, especially in older adults.

The Bottom Line: By supporting heart health, potentially staving off certain cancers, and bolstering the immune system, vitamin D directly reduces the risk of dying from the world’s most common fatal diseases.

3. By Preserving Physical Function: Supporting Muscles and Cognition

Longevity isn’t just about living longer; it’s about living well longer. Vitamin D is critical for maintaining the physical and mental function that defines a healthy, independent life.

  • Muscle Strength & Sarcopenia: Age-related muscle loss (sarcopenia) is a major predictor of frailty, falls, and loss of independence. Vitamin D receptors are present in muscle tissue, and the vitamin is essential for muscle protein synthesis and strength. Deficiency is strongly linked to muscle weakness, pain, and a higher risk of debilitating falls.
  • Brain Health & Cognitive Decline: The brain is rich with vitamin D receptors. Research suggests that sufficient vitamin D may protect against cognitive decline, dementia, and Alzheimer’s disease. Its anti-inflammatory and neuroprotective effects are thought to help clear the amyloid plaques associated with Alzheimer’s and protect neurons from damage.

The Bottom Line: By helping you maintain muscle mass, strength, and cognitive function as you age, vitamin D directly contributes to your “healthspan”—the number of years you live in good health.

Important Caveats and Recommendations

  • Correlation vs. Causation: Much of the evidence is observational, meaning it shows a link but doesn’t prove that vitamin D *causes_ longer life. People with higher levels may also be healthier in other ways (e.g., more outdoor activity, better overall diet).
  • The “Sweet Spot”: More is not always better. The goal is sufficiency, not megadosing. Research has indicated a U-shaped curve, where both deficiency and very high levels can be harmful.
  • What to Do: The best approach is to:
    1. Get Tested: Ask your doctor for a 25-hydroxy vitamin D blood test to know your level.
    2. Sensible Sun Exposure: 10-15 minutes of midday sun on arms and legs a few times a week can help (depending on skin tone and location).
    3. Diet & Supplementation: Eat vitamin D-rich foods (fatty fish, fortified milk, eggs) and consider a supplement if recommended by your doctor, especially during winter months or if you have limited sun exposure.

In summary, research suggests vitamin D may boost longevity not through one magic bullet, but by supporting the fundamental health of your cells, your major organs, and your physical and mental capabilities as you age.

Reference:
https://www.medicalnewstoday.com/articles/3-ways-vitamin-d-may-boost-longevity-according-to-research-edited
https://www.health.harvard.edu/staying-healthy/vitamin-d-and-your-health-breaking-old-rules-raising-new-hopes
https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
https://www.nature.com/articles/s43587-024-00793-y

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https://mygenericpharmacy.com/category/products/disease/vitamins-enzymes

Vitamin D supplements may help improve blood pressure, cholesterol, and insulin

Vitamin D supplements may help improve blood pressure, cholesterol, and insulin

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A recent meta-analysis found that a daily average of 3,320 IU of supplemental vitamin D is linked to lower levels of hemoglobin A1C, total cholesterol, blood pressure, fasting blood glucose, and insulin. The conclusion is based on a recent meta-analysis of 99 international randomized controlled trials that looked into the advantages of vitamin D for cardiometabolic health. The meta-analysis makes an effort to clarify and summarize the results of occasionally contradictory studies on vitamin D.

A fresh perspective on the importance of vitamin D supplementation in preserving cardiometabolic health is extracted from a recent, thorough review of the body of existing, frequently contradictory, research on the subject. A median daily intake of 3,320 International Units (IU) of vitamin D, or about 83 micrograms, was linked to some noteworthy cardiometabolic advantages, according to the meta-study’s authors. Among these advantages were decreases in insulin, fasting blood glucose, hemoglobin A1C, a sign of type 2 diabetes, systolic and diastolic blood pressure, and total cholesterol.

Researchers from the United States and China analyzed data from 99 RCTs (randomized, controlled trials) that were released up until March 26, 2024. 17,656 people took part in the trials, which were conducted in a variety of global locations with widely disparate populations. A crucial element of the meta-analysis involved enumerating the variations among the RCTs that could potentially account for the disparities in their findings. The authors of the meta-study were able to reassess and compare the RTCs’ data more fairly and comparably after those differences were recognized.

Conflicts had less of an impact on the final conclusions, and a few unique cases about particular populations surfaced. The groups that benefited most from vitamin D supplementation, according to the researchers, were non-Westerners, those with lower blood levels of the nutrient, those with a BMI under 30, and those 50 years of age and above.

Why previous findings on vitamin D have been inconsistent
Professor of epidemiology, surgery, and medicine at Brown University in Providence, Rhode Island, Simin Liu, MD, ScD, the corresponding author of the meta-study, outlined some of the ways that the RCTs varied from one another and led to differing conclusions. According to him, some primary causes of heterogeneity in past research that produced contradictory results about supplementation and cardiometabolic risk factors included age, body weight, ethnic background, and the circulating 25[OH]D levels of study participants at enrollment.

The amount of vitamin D, specifically in the form of 25[OH]D, present in one’s bloodstream serves as the most dependable measure of the body’s entire vitamin D reserve, encompassing both naturally produced vitamin D from the skin and vitamin D obtained through dietary supplements. (Citing Trusted Source) Dr. Jayne Morgan, a cardiologist and the Executive Director of Health and Community Education at the Piedmont Healthcare Corporation in Atlanta, GA, who was not associated with the meta-study, pointed out another factor contributing to the medical community’s less than complete confidence in vitamin D.

Although numerous studies show a connection between vitamin D supplementation and a decreased risk of heart disease, a clear cause-and-effect relationship is still missing. Furthermore, it is still unknown if low serum vitamin D levels are a cause or contributing factor to heart disease, or if they are a result of heart disease itself. Low serum vitamin D levels are linked to an increased risk of cardiovascular disease.

However, the data is leaning in this direction, and as of right now, there is no conclusive information on cardiovascular endpoints. According to Morgan, although the data does not meet the criteria for evidence-based information, it does meet the criteria for evidence-informed information. Benefits include improved muscle function, decreased inflammation, and bone health. She went on to say that it may have beneficial effects on lipids, diabetes, and hypertension.

Some benefit more, some need more vitamin D
According to Liu, non-Westerners are more likely to benefit from vitamin D supplementation because they have comparatively lower circulating vitamin D levels. Similarly, serum vitamin D levels tend to decline with age, which could account for the greater cardiometabolic improving effect of vitamin D supplementation seen in individuals 50 years of age and older, he continued. This also applies to those with BMIs under 30 kg. According to Morgan, all of this suggests that the catch-up might be a crucial component of the puzzle.

Individuals with initial vitamin D levels that were not low, and who only managed to increase these levels, had a lesser impact and moved the scale less than those who significantly elevated their vitamin D levels due to their initially low levels. They demonstrated a more substantial shift, as she put it.

A personalized approach to vitamin D
According to Liu, there is undoubtedly validity to the adage One size does not fit all, even in light of the positive associations found for 3,320 IU of vitamin D per day for many individuals and the ethnographic differences noted in the meta-study. Careful assessment of each person’s ethnocultural background and biological features would be necessary to implement personalized intervention strategies to achieve optimal levels of vitamin D for cardiometabolic health, according to Liu.

He pointed out that those with obesity and low 25 OHD levels would probably require higher doses of vitamin D and longer durations of treatment, based on the findings of the meta-study. According to Liu, we might have to investigate the effects of longer intervention periods and higher vitamin D doses on cardiometabolic health outcomes in different populations. These variables include age, body weight, ethnic background, and the circulating 25 OHD levels of study participants at the time of enrollment.

References:
https://www.medicalnewstoday.com/articles/vitamin-d-supplements-may-help-improve-blood-pressure-cholesterol-insulin#A-personalized-approach-to-vitamin-D

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Can protein predict mental decline before Alzhiemer’s sign?

Can protein predict mental decline before Alzhiemer’s sign?

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A protein called NPTX2 that is present in the cerebrospinal fluid may be able to forecast the onset of memory and cognitive issues, according to recent research.

Researchers evaluated people who had initially been in normal mental health but later experienced dementia or mild cognitive impairment (MCI).

According to the study, the quicker start of MCI symptoms was linked to lower levels of NPTX2. The results also demonstrated that NPTX2 levels, like other Alzheimer’s disease-related indicators, appear to fluctuate over time.

Findings from a recent study could be useful for understanding cognitive decline and early Alzheimer’s disease diagnosis.

The levels of a protein called NPTX2 in cerebrospinal fluid (CSF), or more simply put, the fluid surrounding the brain, were evaluated by the researchers in order to better understand the brain changes connected to moderate cognitive impairment and dementia.

Lower levels of NPTX2 were discovered to be associated with a more rapid beginning of cognitive deterioration. Along with other Alzheimer’s disease-related indicators, NPTX2 levels evolved with time.

Alzheimer’s disease indicators in cerebrospinal fluid measurement

The 269 participants in the BIOCARD Study who were initially in good mental health had their brain fluid (CSF) taken by the research team.

These patients were followed for an average of 16.3 years, and their average age at the start of the study was roughly 57.7 years.

Out of these people, 77 subsequently experienced dementia or Moderate cognitive impairment (MCI).

Quantitative parallel reaction monitoring mass spectrometry was used by the researchers to evaluate three similar peptides that make up the NPTX2 protein.

Three other markers—A42/A40, p-tau181, and t-tau—that are frequently linked to Alzheimer’s disease were also measured. These measurements were made using a Lumipulse automated electrochemiluminescence test on the identical CSF samples.

The goal of this data analysis was to help the researchers better understand how these indicators changed over time and whether they might be related to the onset of MCI and dementia in the patients under study.

NPTX2 levels and cognitive issues over time

They discovered that people with lower NPTX2 protein levels in their brain fluid (CSF) exhibited cognitive issues and memory deterioration (MCI) earlier than people with higher NPTX2 protein levels.

Both those who acquired MCI within seven years of the study’s beginning and those who did so later found this link to be substantial.

Even after accounting for other well-known Alzheimer’s disease markers detected in the CSF, the researchers observed that the baseline levels of NPTX2 were able to predict when the symptoms of MCI would manifest.

This implies that the amounts of these markers may be associated with modifications in NPTX2 and may contribute to the emergence of cognitive issues.

According to the study’s first author, Anja Soldan, Ph.D., an associate professor of neurology at Johns Hopkins University, “our study shows that low levels of the protein ‘neuropentraxin 2’ (or NPTX2) measured in the cerebrospinal fluid among cognitively healthy middle-aged and older adults may predict later onset of mild cognitive impairment (MCI).”

“[NPTX2] has been connected to learning and memory in mice in the past. Our findings add to the mounting evidence that low levels of this protein in individuals could signal MCI years before symptoms manifest. Notably, our results demonstrate that low levels of the protein enhance the prediction of cognitive impairment even when traditional Alzheimer’s disease biomarkers (such as those linked to amyloid plaques and tau tangles) and well-established genetic risk factors for late-onset Alzheimer’s disease are taken into account,” according to Dr. Anja Soldan.

According to Dr. Soldan, NPTX2 is “predictive of subsequent symptoms of MCI both within and beyond seven years before symptoms occurred.”

Limitations

The study does have a few drawbacks.

Namely that the majority of the participants were white, educated people with a history of dementia in their families. Therefore, it is uncertain whether the results apply to other populations, according to Dr. Soldan.

Without taking part in the study, Santosh Kesari, Ph.D., a neurologist at Providence Saint John’s Health Centre in Santa Monica, California, and the regional medical director for the Research Clinical Institute of Providence Southern California, told that “identifying blood or CSF biomarkers that predict developing dementia is critical to intervene earlier by preventative approaches or treat at the earliest onset of cognitive issues or even before when patients are aware they have dementia.”

Could this indicate new Alzheimer’s medications?

There is now just one FDA-approved treatment on the market that is known to even slightly reduce the signs of Alzheimer’s disease in its early stages, and there are no known therapies or strategies to avoid the disease, according to Dr. Soldan.

Our research demonstrates that reduced NPTX2 levels exist for many years before MCI or dementia brought on by Alzheimer’s disease, which increases the prospect of creating therapies that specifically target NPTX2.

Additionally, Dr. Soldan added, “Our findings may be relevant to other neurodegenerative diseases since this protein does not appear to be a specific marker for Alzheimer’s disease.”

Although significant work is being done to create sensitive methods of testing NPTX2 in blood rather than cerebrospinal fluid, we are not yet able to routinely measure brain levels of the substance in clinic settings. Another crucial area of research, according to Dr. Anja Soldan, is the factors that affect the levels of NPTX2 in the brain. However, we know very little about these factors.

Dr. Kesari concurred, stating that “NPTX2 may turn out to be a good target of drug development to prevent cognitive decline and will need to be further tested and validated in future studies.”

Future research will examine NPTX2 in more detail. In the end, additional study is required.

REFERENCES:

For Alzheimer’s disease medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?cPath=77_239

Discover the best sources of prebiotics for our body.

Discover the best sources of prebiotics for our body.

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Prebiotics are fibers that your body cannot digest but which can promote the development of healthy bacteria in your stomach. These plant fibers enter your lower digestive tract where they serve as food for the good bacteria in your gut because your body cannot digest them. Though both probiotics and prebiotics are beneficial microorganisms, your digestive system benefits more from probiotics.

Dietary fibres are not all considered prebiotics. Inulin, fructo-oligosaccharides (FOS), and galacto-oligosaccharides (GOS) are examples of well-known prebiotics. Prebiotics can help maintain a healthy digestive system, strengthen your immune system, and encourage the growth of beneficial bacteria in your stomach if you include them in your diet regularly.

Why Prebiotics Are Important?

Although more research is required to fully understand all the ways prebiotics can benefit your body, they are crucial to your health. Prebiotics are occasionally added to diets, but they are naturally present in several high-fiber foods. Additionally, they are offered as dietary supplements.

The amount of food that should be consumed daily is not officially suggested. According to studies, consuming 3 to 5 grammes of prebiotics daily may improve intestinal health. You can probably be confident you’re receiving enough dietary fibre if you consume the required amount.

Leading five prebiotic foods

Researchers examined the prebiotic data of 8,690 distinct food categories in the Food and Nutrient Database for Dietary Studies for this investigation.

According to researchers, prebiotics were present in 37% of the foods in the database. The five items with the highest prebiotic content ranged in concentration from 79 to 243 milligrammes per gramme of food and included:

  • Green dandelion
  • Artichokes of Jerusalem
  • garlic
  • leeks
  • onions

“We weren’t surprised to find that these foods ‘packed the greatest prebiotic punch,’ per se, given that our prior literature review had shown these foods to be high in prebiotics,” said Cassandra Boyd, a master’s student and the study’s presenting author. This research was done in collaboration with Dr. John Gieng, an assistant professor of nutritional sciences in the Department of Nutrition, Food Science & Packaging.

“Having said that, we were astonished to find that relatively small quantities of these meals contained the 5 grams of prebiotics that the International Scientific Association for Probiotics and Prebiotics (ISAPP) recommends consuming daily. For instance, if a small onion weighs around 4 ounces, eating about half of one would provide the recommended 5 grams of prebiotics per day,” according to Boyd.

The study also identified onion rings, creamed onions, cowpeas (commonly known as black-eyed peas), asparagus, and Kellogg’s All-Bran cereal as probiotic-rich foods. Prebiotics are present in all of these foods in amounts of 50–60 milligrams per gram.

Researchers discovered that diets containing wheat had a low prebiotic content. Additionally, the prebiotic content of dairy, eggs, oils, and meat was minimal at best.

What distinguishes prebiotics from probiotics?

Probiotics are microorganisms that are applied to or consumed by humans. They are supposed to provide health benefits such as aiding in the digestion of food and maintaining the balance of your entire body because they are frequently the same “good” bacteria that reside in your gut microbiome.

Alcohol and various drugs, such as antibiotics, can occasionally destroy healthy bacteria, leaving the person with an imbalanced stomach. The microbiota can be brought back into equilibrium by consuming probiotic-rich fermented foods like yogurt, sauerkraut, kefir, and kimchi or by adding probiotics back into the body through supplements.

The probiotic bacteria one consumes as well as the “good” bacteria found in the gut microbiome both require food in order to survive. Prebiotics can help with that.

Prebiotics are types of dietary fibre that the body cannot digest. Probiotics consume them as they pass through the digestive tract in order to survive and develop.

“Prebiotics are healthy precisely because they have been indicated to improve the microbiome,” asserted Boyd. “They are substrates that beneficial bacteria can directly use to confer health benefits on the host, as these bacteria perform functions that are advantageous to human health.”

Prebiotics are known to assist with the following in addition to supporting probiotics:

Prebiotics may aid people with specific conditions including obesity and irritable bowel syndrome, as well as prevent some cancers like colorectal cancer, according to ongoing research.

Additional health advantages of prebiotics

It is not surprising that the five items listed are high in prebiotics, according to Allison Tallman, a registered dietitian and the founder of Nourished Routes, who reviewed this research.

She continued, “These foods are also high in fiber, which is good for gut health as well. Given that these delicacies might not be as well known to the average consumer, I believe people will be interested in learning more about dandelion and Jerusalem artichokes.”

The chief of the gastroenterology division at Hackensack University Medical Centre, Dr. Rosario Ligresti, concurred.

“I was not surprised at all because each of these foods (has) been shown to have many health benefits, so it would make sense they are also good for our gut and our digestion,” the man said.

“Many of these foods, especially Jerusalem artichokes, are high in the indigestible dietary fibre inulin that, when broken down in the gut, release the healthy prebiotic nutrients that get to work to support our digestive health in so many different ways,” explained Dr. Rosario Ligresti.

Can eating prebiotics reduce depression?

The next stage in this research, according to Boyd, is to determine whether there is a connection between prebiotic use and depression as measured by the Patient Health Questionnaire (PHQ9), a validated instrument.

Tallman stated that she would like to see further research on the effects of consuming these particular meals and other foods that are high in prebiotics on the human microbiota.

“Some randomized controlled trials should be conducted to determine the actual health benefits of prebiotics on the human microbiota and to determine its relationship with different disease states. Additionally, there is still a tonne of research to be done on prebiotic use and the relationship between the gut and the brain,” according to registered dietitian Allison Tallman.

And while there is a tonne of existing evidence to suggest that these foods are excellent providers of prebiotics, Dr. Ligresti noted that there can never be enough significant studies conducted over extensive time periods to confirm what we may already suspect.

He continued, “More research into the advantages of a healthy microbiome fostered by these nutrients are also necessary, particularly how changing the microbiota can help cancer patients and those with autoimmune illnesses.”

REFERENCES:

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