Browsed by
Tag: heart disease

Is it possible to have Angina with normal blood pressure?

Is it possible to have Angina with normal blood pressure?

What is Angina?

Angina is tightness, squeezing, pressure, or pain in the chest. It occurs when an area of the heart muscle receives less blood oxygen than usual. It is not a disease but a symptom. Angina usually happens due to ischemia, when one or more of the coronary arteries becomes narrow or blocked. It is often a symptom of coronary heart disease (CHD).

Alone, angina is not life threatening, but it can resemble the symptoms of a heart attack, and it is a sign of heart disease. Receive medical attention if angina occurs unexpectedly, does not go away, or does not respond to rest or medication.

What does angina feel like?

Most angina sufferers describe having pressure or pain in the chest. Or they describe a heaviness or squeezing in their chest. Some claim that it has the sensation of dyspepsia. Others claim that putting angina into words is difficult.

Usually, the pain starts behind your breastbone. You might not always be able to pinpoint the particular source of the pain. Your upper torso may experience upper chest pain or discomfort as well. Your neck, jaw, shoulders, arms, back, and belly are a few of these.

Other symptoms, referred to as “angina analogues,” can be brought on by a lack of oxygen to your heart. You may not feel any of these symptoms in your chest, such as:

Types of Angina

Enduring angina

When the heart is working harder than usual, such as during exercise, stable angina develops. Normally, it lasts for five minutes.

It has a predictable rhythm and might last for weeks, months, or even years. The symptoms can typically be reduced with rest or medicine.

Erratic angina

Unstable angina has no set rhythm and typically strikes while you’re at rest. Atherosclerosis, which involves a blockage preventing blood from reaching the heart, is the primary cause.

The pain may develop with time and linger for more than five minutes. Medication and rest may not be enough to reduce the symptoms.

Angina that is unstable can signal a possible heart attack. Anyone experiencing sudden angina should seek emergency medical attention.

Angina microvascular

Coronary microvascular disease can cause microvascular angina (MVD). The tiniest coronary arteries are impacted by this.

In addition to chest pain, a person may feel:

  • low energy and weariness
  • issues with sleep
  • breathing difficulty
  • Stable angina is more transient than microvascular angina. It frequently lasts for more than ten minutes. Trustworthy Source and occasionally takes more than 30 minutes.

Angina variant

Rare variant angina Prinzmetal angina is the name some doctors give to this condition, which can occur when the body is at rest, usually in the early morning or late at night.

It takes place when the coronary arteries spasm. Cold exposure, stress, medications, smoking, or cocaine usage are examples of potential triggers. Although the illness is chronic, medicines can help manage it.

What causes angina?

Angina is brought on by myocardial ischemia, which is reduced blood supply to the heart. Your coronary arteries may develop a number of issues that hinder your heart from getting adequate blood. These consist of:

Coronary artery disease: The most frequent cause of angina is coronary artery disease. When plaque (a fatty, waxy substance) accumulates in your coronary arteries, which carry blood to your heart, it causes heart disease. Your heart receives less blood as a result of these arteries’ narrowing or hardening (atherosclerosis).

Coronary microvascular disease: Compared to men and individuals designated male at birth, women and people assigned female at birth (AFAB) had a higher prevalence of coronary microvascular disease (AMAB). Small blood veins that branch off of your coronary arteries suffer damage to their walls.

Coronary artery spasm: Your coronary arteries repeatedly contract (tighten) and then relax during a coronary artery spasm. Your heart’s blood supply is momentarily restricted by these spams. Even without coronary artery disease, you can experience coronary spasms. Regular CAD testing may not be able to diagnose this, and it may be necessary to conduct specialised testing that not all hospitals offer.

Angina with normal blood pressure?

Even though the coronary arteries themselves are healthy, angina can occasionally develop when parts of the heart muscle are not getting enough oxygen.

The following conditions can cause angina without having coronary artery disease:

  • extremely low blood pressure, which may happen in shock as a result of bleeding
  • severe anaemia
  • extremely active effort
  • a lot of mental stress (as in broken heart syndrome)
  • significant hyperthyroidism
  • persistent tachycardia
  • significant hypertension (high blood pressure)
  • severely enlarged ventricles
  • significant aortic stenosis

These disorders typically affect sicker people, and angina is typically just one symptom among many. Therefore, the absence of classic CAD is unlikely to mislead the healthcare professionals caring for these patients into a false sense of complacency.

REFERENCES:

For more details, kindly visit below.

Is there any side effects of using too much Cinnamon?

Is there any side effects of using too much Cinnamon?

What is Cinnamon?

On toast and in lattes, cinnamon is a spice. But for thousands of years, extracts from the cinnamon tree’s bark, leaves, blossoms, fruits, and roots have also been utilised in traditional medicines all throughout the world. It is added to many foods and used in baking and cooking.

The four main types of cinnamon are as follows. The variety of cinnamon that is most frequently offered in the US is cassia, which is darker in colour. Southeast Asia is where it is raised. True cinnamon, commonly referred to as Ceylon cinnamon, is widely utilised abroad.

One of the two primary varieties of cinnamon i.e. Ceylon or Cassia, or a combination of the two—could be the cinnamon you purchase at the shop. Ceylon is easier to grind, but its health benefits might not be as good.

Health Benefits of Cinnamon

Cinnamaldehyde is one of the most significant active components in cinnamon. It is utilised in scents and flavourings. It might be the cause of some of cinnamon’s potential health advantages.

According to certain studies, cinnamon may benefit diabetics. According to a study of 18 studies, cinnamon may help reduce blood sugar levels. Hemoglobin A1C, a marker of blood sugar levels over time, was unaffected, nevertheless. In diabetics, it may also decrease cholesterol.

Numerous studies lack information about the sort of cinnamon they used or have other issues that cast doubt on the accuracy of their conclusions. According to one analysis, cinnamon may aid in reducing obesity and weight gain. Irritable bowel syndrome and other stomach and intestinal issues are occasionally treated with it. But its effectiveness is unclear.

Cinnamon has been proposed to be beneficial for

  • Heart condition
  • Alzheimer’s condition
  • Cancer
  • HIV
  • Infection
  • dental decay
  • Allergies

However, a large number of research have used animal or cell models. Although cinnamon has anti-inflammatory, antibacterial, and antioxidant properties, there are currently insufficient studies to support their effectiveness in treating human conditions.

Side effects of Cinnamon

Cinnamon consumption in moderation is unlikely to have a significant negative influence on your health. Consuming excessive amounts of it is also not recommended.

There is no established dosage for cinnamon because it is an unproven treatment. Some experts advise taking 2-4 grammes of powder, or 1/2 to 1 teaspoon, per day. The amount of cinnamon used in some studies ranged from 1 to 6 grams. High doses could be harmful.

May Cause Liver Damage

A 130-pound (59-kg) person can consume 5 mg of coumarin daily, or approximately 0.05 mg per pound (0.1 mg per kilogramme) of body weight. Accordingly, consuming even a single teaspoon of cassia cinnamon could cause you to exceed the daily limit.

Unfortunately, a number of research have revealed that consuming too much coumarin may harm and poison the liver.

As an illustration, after only one week of taking cinnamon supplements, a 73-year-old woman experienced a sudden liver infection that resulted in liver damage. But in this instance, the dose was larger because of the supplements used than it would be from food alone.

May Increase the Risk of Cancer

An excessive intake of coumarin, which is present in large quantities in Cassia cinnamon, has been linked to an increased risk of some malignancies in animal experiments.

For instance, research on rodents has revealed that consuming too much coumarin might result in the growth of malignant tumours in the lungs, liver, and kidneys. It’s unclear how coumarin might result in tumors.

However, some scientists think that over time, DNA damage brought on by coumarin increases the risk of cancer.

May Cause Mouth Sores

Mouth sores have been reported in certain consumers after consuming items with cinnamon flavouring.

When taken in excessive quantities, the chemical cinnamaldehyde found in cinnamon may cause an allergic reaction. Small doses of the spice don’t appear to trigger this reaction because saliva keeps chemicals from coming into prolonged contact with the mouth.

Other signs of a cinnamaldehyde allergy besides mouth sores include:

  • tongue or gum enlargement
  • a feeling of burning or itching
  • mouth with white spots
  • Although not always serious, some symptoms can nonetheless be uncomfortable.

It’s crucial to remember that cinnamaldehyde only causes mouth sores in people who are allergic to it. A skin patch test can be used to check for this kind of allergy.

May Cause Low Blood Sugar

It is commonly known that cinnamon can reduce blood sugar levels. According to studies, the spice can replicate the actions of the hormone insulin, which aids in removing sugar from the blood.

Although consuming a small amount of cinnamon may help lower blood sugar, doing so excessively may cause it to drop too low. It is known as hypoglycemia. It may cause fatigue, wooziness, and even fainting.

Those who are taking diabetes treatments are particularly at risk of having low blood sugar. This is due to the possibility that cinnamon could intensify the effects of these drugs and cause your blood sugar to drop too low.

May Cause Breathing Problems

This is so that it won’t be difficult to inhale due to the spice’s fine texture. Its accidental inhalation can result in:

  • coughing
  • gagging
  • trying to catch your breath is difficult

Additionally, the cinnamaldehyde in cinnamon irritates the throat. It might result in additional respiratory issues. Being unintentionally exposed to cinnamon should be avoided by those who have asthma or other breathing-related illnesses because they are more prone to have breathing difficulties.

Interact with Certain Medications

With the majority of drugs, cinnamon is safe to consume in small to moderate doses. If you are taking medication for diabetes, heart disease, or liver disease, taking too much may be a problem. This is due to the possibility that cinnamon may interact with such drugs, either amplifying their effects or causing more severe side effects.

For instance, cassia cinnamon has a lot of coumarin, which is poisonous to the liver and might harm it if ingested in large quantities.

A lot of cinnamon may increase your risk of liver damage if you use drugs that could harm your liver, like paracetamol, acetaminophen, and statins.

REFERENCES:

For more details, kindly visit below.

What happens when you take Xenical to treat Obesity?

What happens when you take Xenical to treat Obesity?

Obesity

Obesity is a complex disease characterised by an excess of body fat. Obesity is more than just a cosmetic issue. It is a medical condition that raises the risk of developing other diseases and health issues, such as heart disease, diabetes, high blood pressure, and certain cancers.

Some people struggle to lose weight for a variety of reasons. Obesity is typically caused by a combination of inherited, physiological, and environmental factors, as well as dietary, physical activity, and exercise choices.

Reports about Obesity

Following are some recent WHO global estimates.

  • In 2016, over 1.9 billion adults aged 18 and up were overweight. Over 650 million of these adults were obese.
  • 39% of adults aged 18 and up were overweight (39% of men and 40% of women), in 2016.
  • Approximately 13% of the world’s adult population (11% of men and 15% of women) in 2016 were obese.
  • Between 1975 and 2016, the global prevalence of obesity nearly tripled.
  • An estimated 38.2 million children under the age of five were overweight or obese in 2019. Overweight and obesity, once thought to be a problem only in high-income countries, are now on the rise in low- and middle-income countries, particularly in urban areas.
  • Since 2000, the number of overweight children under the age of five has increased by nearly 24% in Africa. In 2019, Asia was home to nearly half of all children under the age of five who were overweight or obese. Over 340 million children and adolescents aged 5 to 19 in 2016 were overweight or obese.

Causes of Obesity

Obesity and overweight are caused by an energy imbalance between calories consumed and calories expended. There has been worldwide:

  • an increase in the consumption of energy-dense foods high in fat and sugars; 
  • and an increase in physical inactivity as a result of the increasingly sedentary nature of many types of work, changing modes of transportation, and increasing urbanisation.

Environmental and societal changes associated with development, as well as a lack of supportive policies in sectors such as health, agriculture, transportation, urban planning, environment, food processing, distribution, marketing, and education, frequently cause changes in dietary and physical activity patterns.

Xenical

Orlistat is a medical drug, available to us under the brand name Xenical that belongs to a class of medication called Lipase inhibitors. This medicine is used to promote weight loss by decreasing the amount of fat that is absorbed in your intestine, generally dietary. It works by breaking the dietary fat into smaller compounds so that it can be used or stored for future energy. 

Xenical is available to us in a form of pill that must be taken by mouth with or without food as per your doctor’s prescription. The dosage is based on your medical condition, its response to the treatment, and other medicine that you may be taking along with Xenical. Your doctor may start the dosage low and may increase it gradually after some while. Take the medicine at the same time daily to get the most benefits from it. Do not increase the dosage or take it more often than prescribed. Contact your doctor in case of any confusion or exception associated with medication.

Side effects of Xenical

Common side effects an individual may observe while medicating with Xenical are oily spotting, intestinal gas discharge, several bowel movement disorders, may occur. Inform the doctor if these conditions persist or get worse.

There are some serious side effects which must be informed to the doctor right away if observed such as blurred vision, dark urine, stomach/abdominal pain, eyes/skin yellowing, easy bruising/bleeding, symptoms of kidney stones, etc.

Also, there are some severe allergic reactions involved with this medicine which require immediate medical attention if observed such as severe dizziness, facial itching/swelling, trouble breathing, rashes, etc.

Precautions before using Xenical

Tell your doctor or pharmacist if you are allergic to orlistat or if you have any other allergies before taking it. Inactive ingredients in this product may cause allergic reactions or other problems. More information can be obtained from your pharmacist.

Inform your doctor or pharmacist of your medical history, particularly of:

  • a digestive problem (chronic malabsorption syndrome),
  • kidney stones/problems (such as calcium oxalate kidney stones, hyperoxaluria),
  • an underactive thyroid (hypothyroidism),
  • seizures,
  • anorexia nervosa/bulimia,
  • HIV infection,
  • a gall bladder problem (cholestasis).

Also, inform your doctor or dentist about all of the products you use before having surgery (including prescription drugs, nonprescription drugs, and herbal products).

If you have diabetes, losing weight may help you control your blood sugar levels. Check your blood sugar levels on a regular basis anda report the results to your doctor. Your diabetes medication, exercise programme, or diet may need to be adjusted by your doctor.

This medication should not be taken while pregnant. Weight loss has no potential benefits for pregnant women and may harm the unborn child. Inform your doctor right away if you become pregnant or suspect you are pregnant.

REFERENCES:

For more details, kindly visit below.

What’s the relation between Metabolic syndrome and ED?

What’s the relation between Metabolic syndrome and ED?

Summary

Erectile dysfunction (ED) is characterized by an inability to maintain an erection sufficient for a satisfactory sexual encounter. The metabolic syndrome is a constellation of symptoms that increases the risk of heart disease in patients. Studies have linked the metabolic syndrome to ED.

The presence of ED is an important indicator that a patient may be at risk for a cardiovascular event within five years of onset. In the same way, metabolic syndrome has multifactorial causes, so it may also have multifactorial effects on erectile function. The purpose of this blog is to review on how metabolic syndrome and its components are associated with ED. Also, whether interventions targeted at improving metabolic syndrome components can improve the condition.  

Introduction

A man with erectile dysfunction (ED) is unable to achieve and/or maintain an erection sufficient for satisfactory sexual performance. ED is the most commonly treated sexual dysfunction in men worldwide. It is found in 15% of men between 40 and 50 years old. Also in 45% of men between 60 and 70 years old, and 70% of older men.

The association between ED and cardiovascular disease (CVD) has been documented for the past decade. It may be difficult to establish causality, but ED appears to be an indicator of systemic disease, with both ED and CVD arising from the same cause.

What is Erectile dysfunction?

Erectile dysfunction is basically a disorder found in men which could be a sign of physical or psychological condition. The symptoms associated with this disorder is found in men’s reproductive organ i.e. inability to keep an erection firmer and longer enough during a sexual activity.

There are many men who experience erectile dysfunction occasionally because of stress, fatigue, alcohol, or emotional issues, but 25% of men have recurring episodes of the disorder. People dealing with erectile dysfunction will be:

  • Unable to achieve erection at anytime needed.
  • might achieve erection sometime but not when needed like during sexual activity.
  • might able to achieve erection when needed but not long enough

What is Metabolic Syndrome?

A metabolic syndrome is a collection of conditions that occur together, increasing your risk of type 2 diabetes, heart disease, and stroke. A number of conditions are associated with obesity, including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.

The presence of just one of these conditions does not necessarily indicate metabolic syndrome. It does, however, increase your risk of serious diseases. In addition, if you develop more of these conditions, you face a greater risk of complications, such as type 2 diabetes and heart disease.

Link between ED and Metabolic syndrome

Metabolic syndrome has attracted considerable attention as a result of its increasing association with various pathophysiologic conditions, including heart failure, type 2 diabetes, and erectile dysfunction. It has been shown in numerous studies that various components of the Metabolic syndrome are directly correlated with ED.

Additionally, an independent association between components of Metabolic syndrome and ED was found in the study. Kupelian et al. showed that even at a BMI of 25, Metabolic syndrome is associated with an increased ED risk (relative risk = 2.09) using data from the Massachusetts Male Aging Study.

An analysis of adult participants in the 2001–2004 National Health and Nutrition Examination Survey revealed an association between poor glycemic control, impaired insulin sensitivity, and the Metabolic syndrome and an increased risk of ED.

Conclusion:

To prevent or control the epidemic trend of the Metabolic syndrome and its consequences, strategies must be developed. Identification and treatment of at-risk individuals early could aid in the improvement of ED and secondary cardiovascular disease, such as weight management, lifestyle changes, and physical activity. There have been several studies that have demonstrated the effectiveness of the intervention. In a recent study, Esposito et al. found that a Mediterranean-style diet is beneficial in reducing the prevalence of ED in men with Metabolic syndrome, as it is rich in whole grain, fruits, vegetables, legumes, walnuts, and olive oil.

REFERENCES:

For more details, kindly visit below.