A new study suggests that people with a higher biological age (how old their cells and systems appear) compared to their chronological age (actual years lived) may face a greater risk of developing dementia.

Key Findings:

Epigenetic Clocks & Dementia Risk

• Researchers used DNA methylation clocks (measuring biological age) and found that individuals with accelerated aging had a higher likelihood of dementia.
• Even after adjusting for genetics and lifestyle factors, biological age was a stronger predictor than chronological age.

Potential Reasons for the Link

• Cellular Damage Accumulation – Faster biological aging may lead to earlier brain cell deterioration.
• Increased Inflammation & Oxidative Stress – Accelerates neurodegeneration.
• Vascular Health Decline – Impacts blood flow to the brain.

What Can Slow Biological Aging?

Regular Exercise (even moderate activity helps)
Heart-Healthy Diet (Mediterranean diet is linked to slower aging)
Quality Sleep (7-9 hours supports cellular repair)
Stress Management (Chronic stress speeds up epigenetic aging)
Avoiding Smoking & Excessive Alcohol

Reference:

https://www.sciencedaily.com/releases/2023/11/231106134925.htm

https://pmc.ncbi.nlm.nih.gov/articles/PMC10690013

https://www.medicalnewstoday.com/articles/higher-biological-age-may-increase-dementia-risk-study

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