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Month: July 2025

Eating eggs weekly may lower Alzheimer’s risk by nearly 50%: Study

Eating eggs weekly may lower Alzheimer’s risk by nearly 50%: Study

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A recent study has suggested that eating just one egg per week may be associated with a reduced risk of developing Alzheimer’s disease. Here’s a breakdown of the findings and what they could mean:

Key Findings:

  • Lower Alzheimer’s Risk: Researchers observed that participants who consumed at least one egg per week had a significantly lower risk of Alzheimer’s compared to those who ate eggs less frequently or not at all.
  • Possible Protective Nutrients: Eggs are rich in choline, lutein, zeaxanthin, and omega-3 fatty acids, which are believed to support brain health by reducing inflammation, improving neuronal function, and protecting against oxidative stress.
  • Moderation Matters: The study did not suggest excessive egg consumption but highlighted that even a modest intake (one per week) might offer benefits.

Study Details:

  • Type of Study: Likely an observational study (cohort or case-control), meaning it shows an association but does not prove causation.
  • Participants: The research may have tracked older adults over time, comparing dietary habits with cognitive outcomes.
  • Confounding Factors: Other healthy lifestyle habits (exercise, balanced diet) could also contribute to the observed benefits.

Why Eggs Might Help?

  1. Choline: Essential for neurotransmitter production (e.g., acetylcholine, which is critical for memory and declines in Alzheimer’s).
  2. Antioxidants (Lutein & Zeaxanthin): Protect brain cells from damage.
  3. Healthy Fats (DHA): Supports brain cell membrane integrity.

Limitations:

  • Correlation ≠ Causation: The study doesn’t prove eggs prevent Alzheimer’s—other dietary or lifestyle factors may play a role.
  • Individual Variability: Genetics, overall diet, and metabolic health influence outcomes.
  • Including eggs as part of a balanced diet (along with vegetables, whole grains, and healthy fats) may support brain health.
  • If you have cholesterol concerns, consult a doctor, but current research suggests moderate egg consumption is generally safe for most people.

Reference:

https://www.medicalnewstoday.com/articles/eating-1-egg-per-week-linked-to-lower-alzheimers-risk-study-finds

https://www.newsnationnow.com/health/eating-eggs-alzheimers

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/eating-this-breakfast-daily-can-lower-alzheimers-risk-by-almost-half-and-boost-brain-health/articleshow/122624598.cms

Medications that have been suggested by doctors worldwide are available on below link

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These Low-Key Exercises Could Help You Sleep Better

These Low-Key Exercises Could Help You Sleep Better

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If you struggle with insomnia, certain types of exercise can improve sleep quality by reducing stress, regulating circadian rhythms, and promoting relaxation. Here are the three best types of exercise for managing insomnia, backed by research:

1. Moderate Aerobic Exercise (e.g., Brisk Walking, Cycling, Swimming)

  • Why it works:
    • Increases slow-wave (deep) sleep, which is crucial for physical restoration.
    • Reduces cortisol (stress hormone) and raises endorphins.
    • Helps regulate the body’s internal clock, especially if done outdoors in daylight.
  • Best time: Morning or early afternoon (avoid vigorous cardio close to bedtime).

2. Yoga & Mindful Movement (e.g., Hatha Yoga, Tai Chi, Stretching)

  • Why it works:
    • Combines gentle movement with breath control, activating the parasympathetic nervous system (rest-and-digest mode).
    • Reduces anxiety and physical tension, which are common causes of insomnia.
    • Improves sleep latency (time taken to fall asleep).
  • Best time: Evening (slow, restorative yoga 1–2 hours before bed).

3. Strength Training (Resistance/Weight Training)

  • Why it works:
    • Increases growth hormone production, aiding deep sleep.
    • Reduces nighttime awakenings by lowering metabolic stress over time.
    • Helps balance blood sugar, preventing sleep-disrupting crashes.
  • Best time: Morning or late afternoon (avoid heavy lifting right before bed).

Key Tips for Exercise & Insomnia

  • Avoid intense workouts 2–3 hours before bed (can raise core body temperature and adrenaline).
  • Consistency matters—regular exercise (even 30 mins/day) improves sleep more than sporadic sessions.
  • Pair with sleep hygiene: Dim lights, cool room, and no screens post-exercise.

Bonus: Walking in Nature

A 20–30 minute walk in green spaces (especially in sunlight) can reset circadian rhythms and reduce insomnia-linked anxiety.

Reference:

https://edition.cnn.com/2025/07/17/health/insomnia-treatment-exercise-sleep-wellness

https://www.everydayhealth.com/sleep/these-low-key-exercises-could-help-you-sleep-better

https://www.medicalnewstoday.com/articles/3-types-exercise-yoga-tai-chi-walking-may-be-best-managing-insomnia

Medications that have been suggested by doctors worldwide are available on below link

https://mygenericpharmacy.com/category/disease/sleep-disorder

Which is better for losing weight – diet or exercise?

Which is better for losing weight – diet or exercise?

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Yes, for weight loss, diet generally matters more than exercise. While both play important roles, research and practical evidence show that controlling calorie intake is more effective for shedding pounds than increasing physical activity alone. Here’s why:

1. Caloric Deficit is Key

  • Weight loss occurs when you burn more calories than you consume (a caloric deficit).
  • It’s easier to reduce calorie intake by 500 calories/day (e.g., skipping a sugary drink and dessert) than to burn 500 calories through exercise (which might require 45–60 minutes of intense cardio).

2. Exercise Burns Fewer Calories Than People Think

  • A 30-minute run may burn ~250–400 calories, but that can be undone quickly by eating a small snack (e.g., a muffin or a handful of nuts).
  • Many people overestimate exercise’s calorie burn and compensate by eating more, negating the deficit.

3. Diet Directly Controls Fat Storage & Hormones

  • Foods high in refined carbs and sugars spike insulin, promoting fat storage.
  • Protein and fiber-rich diets improve satiety, reducing overall calorie intake.
  • Exercise alone doesn’t compensate for a poor diet’s metabolic effects (e.g., insulin resistance).

4. Exercise is Great, But Not Primarily for Weight Loss

  • Exercise supports weight maintenance, muscle retention, and overall health (heart, mood, metabolism).
  • However, without dietary changes, exercise alone often leads to minimal weight loss.

Practical Takeaways

  • Focus on whole, unprocessed foods (vegetables, lean proteins, healthy fats) and portion control.
  • Combine diet with strength training & cardio to preserve muscle and boost metabolism.
  • Avoid liquid calories (soda, alcohol, sugary coffee) and mindless snacking.

While exercise is crucial for long-term health and fitness, you can’t out-exercise a bad diet. For significant weight loss, prioritize nutrition first, then use exercise to enhance results and maintain your progress.

Reference:

https://www.medicalnewstoday.com/articles/for-weight-loss-diet-may-matter-more-than-exercise

https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-minute-which-is-better-for-losing-weight-diet-or-exercise-video

https://www.healthhub.sg/live-healthy/exercise-vs-diet

Medications that have been suggested by doctors worldwide are available on below link

https://mygenericpharmacy.com/category/weight-loss

Weekly injection could be life changing for Parkinson’s patients

Weekly injection could be life changing for Parkinson’s patients

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Exciting news in Parkinson’s disease (PD) treatment! A new weekly subcutaneous injection is showing promise in clinical trials, potentially replacing daily oral medications for some patients.

Key Highlights:

  • Drug Name: ND0612 (developed by NeuroDerm, now part of AbbVie)
  • How It Works: A continuous, subcutaneous infusion of levodopa/carbidopa (the gold-standard PD treatment), delivering stable drug levels to avoid motor fluctuations.
  • Weekly vs. Daily: Unlike traditional oral levodopa (taken 3-5 times daily), ND0612 is administered via a small pump worn on the body, requiring only weekly refills.
  • Benefits:
    • Reduces “off” periods (when medication wears off)
    • Minimizes dyskinesia (involuntary movements caused by fluctuating drug levels)
    • Improves quality of life by simplifying treatment.

Clinical Trial Results:

  • Phase 3 (BouNDless trial): Showed significant reduction in “off” time compared to oral levodopa.
  • FDA Status: Under priority review, with a decision expected in 2024 or early 2025.

Who Could Benefit?

  • PD patients with advanced symptoms and motor fluctuations despite oral meds.
  • Those struggling with pill fatigue or absorption issues (common in later-stage PD).

Challenges Ahead:

  • Cost & Insurance Coverage: Likely expensive initially.
  • Adoption: Requires patient training on pump use.

Future of PD Treatment:

If approved, ND0612 could join other advanced PD therapies like:

  • Continuous intestinal gel (Duodopa/Duopa)
  • Deep brain stimulation (DBS)
  • Monthly/subcutaneous infusions (e.g., ABBV-951)

Reference:

https://www.medicalnewstoday.com/articles/parkinsons-new-weekly-injection-may-eliminate-need-daily-pills

https://www.unisa.edu.au/media-centre/Releases/2025/weekly-injection-could-be-life-changing-for-parkinsons-patients

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/one-shot-a-week-how-weekly-parkinsons-injection-would-be-a-game-changer-for-patients/articleshow/122480019.cms

Medications that have been suggested by doctors worldwide are available on below link

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WHO recommends a twice-a-year injection for HIV prevention

WHO recommends a twice-a-year injection for HIV prevention

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The World Health Organization (WHO) has pre-qualified lenacapavir (Sunlenca), a long-acting HIV prevention injection, marking a significant step toward its global rollout.

Key Points:

  • Twice-Yearly Dosing: Lenacapavir is administered as a subcutaneous injection every six months, making it a highly convenient option for HIV prevention (PrEP).
  • For High-Risk Groups: It is particularly recommended for key populations at high risk of HIV, including men who have sex with men (MSM), transgender individuals, and sex workers.
  • Alternative to Daily Pills: Unlike daily oral PrEP (e.g., Truvada or Descovy), lenacapavir offers long-lasting protection with fewer adherence challenges.
  • Effectiveness: Clinical trials have shown it to be highly effective in reducing HIV transmission when administered as scheduled.

WHO’s Role:

  • The WHO prequalification (June 2024) helps accelerate access in low- and middle-income countries by allowing procurement by UN agencies and governments.
  • It is part of WHO’s strategy to expand HIV prevention options beyond oral PrEP and the monthly cabotegravir (CAB-LA) injection.

Next Steps:

  • Regulatory approvals in individual countries are still needed.
  • Cost and accessibility will be critical factors in widespread adoption.

Lenacapavir represents a major breakthrough in HIV prevention, offering a discreet, long-acting alternative to daily pills.

Reference:

https://www.who.int/news/item/19-06-2025-fda-approval-of-injectable-lenacapavir-marks-progress-for-hiv-prevention

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/who-recommends-a-twice-a-year-injection-for-hiv-prevention/articleshow/122485320.cms

https://www.medicalnewstoday.com/articles/who-recommends-lenacapavir-twice-yearly-injection-help-prevent-hiv

Medications that have been suggested by doctors worldwide are available on below link

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Gabapentin users may face 85% higher cognitive impairment risk

Gabapentin users may face 85% higher cognitive impairment risk

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A recent study has raised concerns about gabapentin (Neurontin) and its potential link to cognitive impairment, particularly in older adults or those taking higher doses. Here’s what you should know:

Key Findings:

  • 85% Higher Risk: Research suggests gabapentin users may have an 85% increased risk of developing cognitive impairment (e.g., memory loss, confusion, difficulty concentrating) compared to non-users.
  • Stronger in Older Adults: The risk appears more pronounced in older patients (65+), especially those with pre-existing conditions like dementia or kidney dysfunction.
  • Dose-Dependent Effect: Higher doses (e.g., >1,200 mg/day) and long-term use may further elevate risks.

Why Might Gabapentin Affect Cognition?

  • GABA Activity: Gabapentin modulates GABA (a calming neurotransmitter), which may contribute to brain fog or slowed thinking.
  • Sedation & Confusion: Like other CNS depressants, it can cause drowsiness, dizziness, and mental clouding.
  • Kidney Function Impact: Poor kidney clearance (common in aging) can lead to drug accumulation, worsening side effects.

Who Should Be Cautious?

  • Older adults (especially those with dementia or mild cognitive impairment).
  • Patients on multiple CNS-acting drugs (e.g., opioids, benzodiazepines, antidepressants).
  • Those with kidney disease (requires dose adjustments).

What Can Patients Do?

Discuss Alternatives – For nerve pain or seizures, ask about safer options (e.g., pregabalin may have a different risk profile).
Monitor Symptoms – Report memory lapses, confusion, or attention issues to a doctor.
Avoid High Doses – Use the lowest effective dose for the shortest duration.
Check Kidney Function – Ensures proper dosing if kidneys aren’t filtering well.

While gabapentin is effective for nerve pain, epilepsy, and other conditions, this study highlights a potential cognitive risk—especially in vulnerable groups. If you or a loved one is on gabapentin, consult a doctor before making changes, but consider discussing risk vs. benefit if cognitive concerns arise.

Reference:

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/explained-gabapentin-dementia-risk-gabapentins-hidden-side-effectsfrom-pain-relief-to-brain-fog/articleshow/122578137.cms

https://pubmed.ncbi.nlm.nih.gov/40639955

https://www.medicalnewstoday.com/articles/gabapentin-users-may-face-85-higher-risk-of-cognitive-impairment

Medications that have been suggested by doctors worldwide are available on below link

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Eating late in the evening could make blood sugar control harder for the body

Eating late in the evening could make blood sugar control harder for the body

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Yes, eating late in the evening—especially close to bedtime—can make blood sugar control more challenging for several reasons:

1. Reduced Insulin Sensitivity at Night

  • The body’s insulin sensitivity tends to decrease in the evening, meaning it may not process glucose as efficiently as it does earlier in the day.
  • Studies suggest that eating later can lead to higher post-meal blood sugar spikes compared to eating the same meal earlier.

2. Disruption of Circadian Rhythms

  • The body’s internal clock (circadian rhythm) influences metabolism, including insulin secretion and glucose processing.
  • Eating late may misalign with natural metabolic cycles, leading to poorer blood sugar regulation.

3. Increased Risk of Overnight High Blood Sugar

  • Consuming carbohydrates or large meals late can keep blood sugar elevated overnight, which may lead to higher fasting blood sugar the next morning (a phenomenon known as the “dawn effect” in some cases).

4. Potential Weight Gain & Insulin Resistance

  • Late-night eating has been linked to weight gain, which can further worsen insulin resistance over time.
  • Snacking on high-carb or sugary foods at night can contribute to long-term metabolic issues.

Tips for Better Blood Sugar Control at Night:

Finish meals earlier – Aim to eat dinner at least 2-3 hours before bedtime.
Choose balanced meals – Include protein, fiber, and healthy fats to slow glucose absorption.
Avoid high-glycemic snacks – If hungry, opt for nuts, Greek yogurt, or veggies instead of sweets or refined carbs.
Monitor blood sugar – If diabetic or prediabetic, checking levels before bed can help adjust habits.

Reference:

https://www.everydayhealth.com/sleep/eating-a-late-dinner-can-spike-your-blood-sugar

https://www.mayoclinic.org/diseases-conditions/diabetes/expert-answers/diabetes/faq-20058372

https://www.medicalnewstoday.com/articles/eating-late-in-the-evening-could-make-blood-sugar-control-harder-for-the-body

https://pmc.ncbi.nlm.nih.gov/articles/PMC5634913

Medications that have been suggested by doctors worldwide are available on below link

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Slowing aging: Psilocybin helps extend life span in human cells by over 50%

Slowing aging: Psilocybin helps extend life span in human cells by over 50%

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Exciting new research suggests that psilocybin, the psychoactive compound in “magic mushrooms,” may have anti-aging properties—extending the lifespan of human cells by over 50% in lab studies. While this doesn’t mean psilocybin directly makes humans live longer (yet), it opens doors for potential longevity and age-related disease therapies.

Key Findings from the Study:

  • Cell Survival Boost: Human cells treated with psilocybin showed 50% longer survival compared to untreated cells under stress conditions.
  • Reduced Senescence: Psilocybin appeared to delay cellular aging (senescence), a key factor in age-related decline.
  • Anti-Inflammatory & Antioxidant Effects: It may reduce oxidative stress and inflammation, both linked to aging.

How Might Psilocybin Slow Aging?

  1. Activation of Serotonin Receptors (5-HT₂A):
    • Psilocybin binds to serotonin receptors, which may enhance cellular stress resistance and promote longevity pathways.
  2. Mitochondrial Support:
    • Early evidence suggests it could improve mitochondrial function, crucial for energy production and reducing age-related damage.
  3. Epigenetic Modulation:
    • Psilocybin might influence gene expression related to aging, similar to how fasting or rapamycin does.

Caveats & Future Research:

  • Lab Studies Only: So far, results are from cell cultures, not human trials.
  • Dosage & Safety Unknown: High doses could have risks; more research is needed on optimal anti-aging dosing.
  • Not a “Fountain of Youth” Yet: While promising, psilocybin is far from proven to extend human lifespan.

Broader Implications for Longevity Science:

  • Psilocybin joins other hallucinogens (like LSD) being studied for neuroprotection and anti-aging effects.
  • Could it help with Alzheimer’s, Parkinson’s, or frailty? Research is ongoing.

Psilocybin shows exciting potential in slowing cellular aging, but human trials are needed. For now, proven longevity strategies (like exercise, fasting, and NAD+ boosters) remain the best bet.

Reference:

https://www.aol.com/slowing-aging-psilocybin-helps-extend-124100219.html

https://www.livescience.com/health/ageing/i-was-floored-by-the-data-psilocybin-shows-anti-aging-properties-in-early-study

https://www.medicalnewstoday.com/articles/slowing-aging-psilocybin-helps-extend-life-span-human-cells-skin

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2 low-calorie days a week could aid weight loss, blood sugar control in diabetes

2 low-calorie days a week could aid weight loss, blood sugar control in diabetes

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Incorporating two low-calorie days per week (often referred to as intermittent fasting or the 5:2 diet) may help with weight loss and blood sugar control in people with diabetes or prediabetes, according to research. Here’s how it works and its potential benefits:

How It Works:

  • 5 Normal Days: Eat a balanced, healthy diet without strict calorie restrictions.
  • 2 Low-Calorie Days: Consume ~500-800 calories (varies by individual), focusing on high-protein, fiber-rich, and low-glycemic foods to stay full and maintain blood sugar stability.

Potential Benefits for Diabetes & Weight Loss:

  1. Improved Insulin Sensitivity – Fasting periods may help lower insulin resistance, aiding blood sugar control.
  2. Weight Loss – Calorie restriction promotes fat loss, which is crucial for managing type 2 diabetes.
  3. Lower Blood Glucose Levels – Some studies show reduced fasting glucose and HbA1c levels with intermittent fasting.
  4. Reduced Inflammation – May help decrease markers of inflammation linked to metabolic diseases.

Considerations & Precautions:

  • Not for Everyone: People with type 1 diabetes, a history of eating disorders, or those on insulin/medications should consult a doctor before trying this, as fasting can cause hypoglycemia (low blood sugar).
  • Hydration & Nutrient Balance: Stay hydrated and prioritize lean proteins, non-starchy veggies, and healthy fats on low-calorie days.
  • Monitor Blood Sugar: Frequent glucose checks are important to avoid dangerous drops or spikes.

Research Support:

  • A 2023 study in Diabetes Care found that intermittent fasting (including 5:2 diets) led to greater weight loss and HbA1c reductions compared to daily calorie restriction in type 2 diabetes patients.
  • Another 2021 meta-analysis in Clinical Diabetes and Endocrinology suggested that intermittent fasting improved metabolic health in prediabetes and early diabetes.

The 5:2 approach may be a useful tool for weight loss and blood sugar management in some people with type 2 diabetes or prediabetes, but it should be personalized and medically supervised. Always consult a doctor or dietitian before making significant dietary changes, especially if taking diabetes medications.

Reference:

https://www.medicalnewstoday.com/articles/2-low-calorie-days-a-week-could-aid-weight-loss-blood-sugar-control-in-diabetes

https://pmc.ncbi.nlm.nih.gov/articles/PMC8756303

https://www.sciencedaily.com/releases/2025/07/250715043351.htm

Medications that have been suggested by doctors worldwide are available on below link

https://mygenericpharmacy.com/category/weight-loss

Study Finds Mediterranean or Plant-Based Diets May Help Reduce Risk of Chronic Constipation in Middle- and Older-Age Adults

Study Finds Mediterranean or Plant-Based Diets May Help Reduce Risk of Chronic Constipation in Middle- and Older-Age Adults

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Yes! Research suggests that Mediterranean and plant-based diets may help reduce the risk of constipation, particularly as people age. Here’s what the evidence shows and why these diets may be beneficial:

Key Findings:

  • Higher Fiber Intake: Both Mediterranean and plant-based diets emphasize fruits, vegetables, whole grains, legumes, nuts, and seeds, all of which are rich in dietary fiber. Fiber adds bulk to stool and promotes regular bowel movements.
  • Healthy Fats: The Mediterranean diet includes olive oil and omega-3s (from fish, nuts), which may improve gut motility and reduce inflammation in the digestive tract.
  • Prebiotics & Probiotics: Fermented foods (like yogurt, kefir) and fiber-rich plants support gut microbiome health, aiding digestion.
  • Hydration: These diets encourage high water intake (from soups, fruits, and vegetables), which softens stool.

Evidence from Studies:

  1. Mediterranean Diet & Constipation:
    • A study in The American Journal of Clinical Nutrition (2020) found that older adults following a Mediterranean diet had better bowel movement frequency and softer stools.
    • Another study linked high olive oil consumption to improved gut transit time.
  2. Plant-Based Diets & Gut Health:
    • Research in Nutrients (2021) showed that vegetarians and vegans had lower constipation rates due to higher fiber intake.
    • A meta-analysis found that plant-based diets increase beneficial gut bacteria, which aid digestion.

Why It Matters for Aging Adults:

  • Age-Related Slowing of Digestion: As people get older, gut motility decreases, and medications (like opioids or diuretics) can worsen constipation.
  • Chronic Constipation Risks: Linked to hemorrhoids, diverticulosis, and even colorectal issues over time.

Practical Tips to Prevent Constipation:

✔ Increase Fiber Gradually (25–30g/day) – beans, oats, berries, flaxseeds.
✔ Stay Hydrated – water, herbal teas, watery fruits (melon, cucumbers).
✔ Include Healthy Fats – olive oil, avocados, nuts.
✔ Exercise Regularly – walking stimulates bowel movements.
✔ Probiotic Foods – yogurt, sauerkraut, kimchi.

Caveats:

  • Too much fiber too quickly can cause bloating; increase intake slowly.
  • Some plant-based foods (like bananas or white rice) may be binding if not balanced with enough water.

Switching to a Mediterranean or plant-based diet can be a natural, effective way to prevent constipation as you age, thanks to their high fiber, hydration, and gut-friendly nutrients.

Reference:

https://www.drugs.com/news/mediterranean-plant-based-diets-could-lower-risk-constipation-125851.html

https://www.medicalnewstoday.com/articles/mediterranean-plant-based-diets-may-reduce-chronic-constipation-risk-aging

https://medicaldialogues.in/gastroenterology/news/study-finds-mediterranean-or-plant-based-diets-may-help-reduce-risk-of-chronic-constipation-in-middle-and-older-age-adults-151349

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