Understanding Arthritis and Inflammation

Understanding Arthritis and Inflammation

The body’s white blood cells and substances that they produce to protect our bodies from infection by foreign organisms, such as bacteria and viruses. In some inflammatory diseases, however, the body’s defense system, the immune system, triggers a response when there are no foreign substances to fight off. In these diseases, called autoimmune disorders, the body’s normally protective immune system causes damage to its own tissues. The body responds as if normal tissues are infected or somehow abnormal.


Understanding the relationship between arthritis and inflammation is key to managing these conditions. In simple terms, all arthritis involves the joints, but not all arthritis is primarily driven by inflammation. Inflammation is a core player in many, but not all, types of arthritis.

Some, but not all, types of arthritis are the result of misdirected inflammation. Arthritis is a general term that describes inflammation in the joints. Some types of arthritis associated with inflammation include the following:
Rheumatoid arthritis
Psoriatic arthritis
Gouty arthritis
Other painful conditions of the joints and musculoskeletal system that may not be associated with inflammation include osteoarthritis, fibromyalgia, muscular low back pain, and muscular neck pain.


Inflammation occurs when substances from the body’s white blood cells are released into the blood or affected tissues to protect your body from foreign invaders. This release of chemicals increases the blood flow to the area of injury or infection, and may result in redness and warmth. Some of the chemicals cause a leak of fluid into the tissues, resulting in swelling. This protective process may stimulate nerves and cause pain. The increased number of cells and inflammatory substances within the joint cause irritation, swelling of the joint lining, and eventual wearing down of cartilage (cushions at the end of bones).

Inflammatory diseases are diagnosed after careful evaluation of the following:
Complete medical history and physical exam with attention to the location of painful joints
Presence of joint stiffness in the morning
Evaluation of accompanying symptoms and signs
Results of X-rays and laboratory tests


Can Inflammation Affect Internal Organs?
Inflammation can affect organs as part of an autoimmune disorder. The type of symptoms experienced depends on which organs are affected. For example:
Inflammation of the heart (myocarditis) may cause shortness of breath or fluid retention.
Inflammation of the small tubes that transport air to the lungs may cause shortness of breath.
Inflammation of the kidneys (nephritis) may cause high blood pressure or kidney failure.
Pain may not be a primary symptom of an inflammatory disease, because many organs do not have pain-sensitive nerves. Treatment of organ inflammation is directed at the cause of inflammation whenever possible.

There are several treatment options for inflammatory diseases, including medications, rest, exercise, and surgery to correct joint damage. The type of treatment prescribed will depend on several factors, including the type of disease, the person’s age, the type of medications they are taking, overall health, medical history, and severity of symptoms.


The goals of treatment are the following:

Correct, control, or slow down the underlying disease process
Avoid or modify activities that aggravate pain
Relieve pain through pain medications and anti-inflammatory drugs
Maintain joint movement and muscle strength through physical therapy
Decrease stress on the joints by using braces, splints, or canes as needed

Reference:
https://my.clevelandclinic.org/health/diseases/12061-arthritis
https://www.webmd.com/arthritis/understanding-arthritis-treatment
https://www.mayoclinic.org/diseases-conditions/arthritis/symptoms-causes/syc-20350772

Medications that have been suggested by doctors worldwide are available on the link below
https://mygenericpharmacy.com/category/products/disease/inflammation
https://mygenericpharmacy.com/category/arthritis

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