Browsed by
Tag: depression

Can a daily brief walk could help with depression?

Can a daily brief walk could help with depression?

Comments 0 Comment

Exercise can enhance brain health, lower disease risk, build bones and muscles, and manage weight.

There is mounting evidence that it can also reduce the signs and symptoms of depression, the main disorder connected to mental health. However, opinions on how much exercise is necessary to have a positive impact vary.

Now, a 10-year research in Ireland has discovered that even little quantities of exercise, like a daily 20-minute stroll, can help older persons experience less despair.

Depression, one of the most prevalent mental health illnesses, is characterized by a persistent sense of emptiness, sadness, or an inability to experience a pleasure. The World Health Organisation (WHO) estimates that it affects about 5% of adults globally.

In 2020, there were 21 million individuals in the United States (8.4% of all adults), and women were more likely than males to experience serious depressive episodes.

According to official government figures, one in six adults in the United Kingdom reported having depressed symptoms in 2021–2022.

Depending on the type of depression a person is dealing with, there are several treatments available, such as antidepressants, psychotherapy like cognitive behavioural therapy (CBT), or a combination of therapy and medicine. Many people find them to be helpful, but once treatment is discontinued, depression may recur.

A little exercise can make a big difference.

There is mounting evidence that altering one’s lifestyle helps lessen depression symptoms. A diet rich in fruit, vegetables, seafood, and whole grains may be linked to a lower incidence of depression, according to a 2014 analysis of 21 research. Additionally, a 2022 analysis of studies revealed that exercise reduced the symptoms of depression.

How much exercise is necessary to reduce depression, however, has not been the subject of many studies.

Now, a ten-year study has discovered that even little exercise helps lessen depression in older persons, defined as those who are 50 years of age and older.

The Health Research Board (HRB) Ireland-funded study, which is published in JAMA Network Open, discovered that a 20-minute brisk walk five times a week dramatically decreased the incidence of depression.

The University of Limerick in Ireland’s Dr. Eamon Laird, the study’s author, explained why the group conducted the investigation:

“Unfortunately, depression is becoming more common in older adults and is linked to a higher risk of developing chronic illnesses like cardiovascular disease (CVD), cognitive decline, death, and suicide. Previous studies have linked physical activity to a lower risk of depression, but no one has ever looked into the absolute minimum amount of physical activity that might be beneficial.

Exercise in general lessens depression

The Irish Longitudinal Study on Ageing (TILDA), a sizable longitudinal study with the goal of enhancing Irish citizens’ ageing experiences, provided the researchers with 4,016 participants. They gathered information between October 2009 and December 2018 at five different intervals.

The researchers used self-completed questionnaires, nurse health assessments, or interviews to gather thorough data on demographic, health, lifestyle, and social aspects at each time point.

The Centre for Epidemiological Studies Depression (CES-D) short form was used to evaluate depressive symptoms. Using this information, they defined major depression as either having a CES-D score more than or equal to nine and/or experiencing a major depressive episode at any moment throughout the data collection process.

Participants self-reported their physical activity over the previous seven days at each data point. They were to keep track of the days they engaged in vigorous, moderate, and walking activities as well as the duration of those activities.

After estimating each person’s weekly total of MET minutes, the researchers divided them into three groups based on their level of physical activity: low, moderate, and high.

Dr. Laird informed us, “We found that older adults who engaged in as little as 20 minutes of moderate to vigorous physical activity (MVPA) per day (for five days a week) had a 16% lower risk of depressive symptoms and a 43% lower odds of depression than those engaging in no exercise.”

The benefits grew as the researchers’ exercise levels rose in each of the three exercise categories. The most active people had a 20% lower chance of developing depression than the least active people.

Even individuals who exercised infrequently had a 16% lower risk of depression than those who did not exercise at all.

Exercise, chronic illness, and depression

Dr. Laird noted that exercise reduced the probability of both depressive symptoms and major depression in people with chronic diseases, and that the benefit grew with increased activity levels.

The WHO standards threshold of 30 minutes a day [per] 5 days [a] week for depressed symptoms was met by participants, specifically for those with chronic conditions, albeit the biggest decreases came with increasing exercise dose, according to the study.

He continued, “In essence, those with chronic diseases may find more benefits. It might be several pathways, including anti-inflammatory, immunological function, heart-brain communication, enhanced muscle performance, etc.”

The study’s non-participant, Dr. Thomas MacLaren, a consultant psychiatrist at Re: Cognition Health, applauded the results.

Chronic health conditions are known to worsen depression and may possibly increase one’s likelihood of getting depressed. The study’s conclusion that there was a dose-dependent association for this group is really positive and shows that adding more brisk walking to your daily routine will help you feel better, he said.

The benefits of exercise for mental health.

Exercise may lower the chance of getting depression or lessen depressive symptoms for a number of reasons.

Exercise improves blood flow to the brain, lowers stress reactivity, and stimulates the hypothalamic-pituitary-adrenal (HPA) axis, which affects motivation and mood. Endorphins, the body’s natural pain and stress relievers, are also produced in greater quantities.

As Dr. MacLaren noted, the impacts go beyond the physical.

Exercise raises fitness levels and encourages the body to release endorphins. Your mood can be elevated naturally by these advantageous consequences. Additionally, it may indirectly improve your daily routine and increase social contact, both of which are crucial in the fight against depression.

Dr. Laird concurred, pointing out that for maximum effect, exercise should be a component of a healthy lifestyle.

“Try to incorporate [exercise] into a routine with hobbies or activities that you enjoy, and we would recommend doing it with others as social interactions, particularly with activity, can also have additional benefits for your mental health,” he advised.

“Remember that it is one component and that nutrition and a healthy lifestyle will also give additive benefits in addition to the physical activity,” said Dr. Laird.

REFERENCES:

For Depression medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?cPath=77_478

Depression: High blood sugar and lower grey matter links.

Depression: High blood sugar and lower grey matter links.

Comments 0 Comment

Around the world, 5% of adults are thought to be depressed. A known risk factor for depression is fluctuations in a person’s blood sugar levels.

The relationship between blood sugar levels and the likelihood of developing depression, according to Sun Yat-sen University researchers, may be mediated by decreased grey matter volume in the brain.

About 5% of the adult population worldwide suffers from depression, a mental illness that makes a person feel incredibly depressed and hopeless to the point where they are unable to enjoy their daily activities.

Variations in glycemia, or a person’s blood sugar levels, are one of the many risk factors for depression.

According to earlier research, people with diabetes, a disorder in which a person struggles to maintain adequate blood sugar levels, are two to three times more likely to experience depression.

The relationship between blood sugar levels and depression may now have a precise biological cause. This is according to researchers from Sun Yat-sen University in Guangzhou, China.

According to research, the association between blood sugar levels and the risk of depression may be mediated by a decreased grey matter volume in the brain.

Depression, blood sugar, and brain structure

According to Dr. Hualiang Lin, a professor in the Department of Epidemiology at Sun Yat-sen University and the study’s corresponding author, they chose to investigate the effect of blood sugar on the risk of developing depression. Earlier research has established a link between changes in blood sugar levels and the development of depression.

Also, a lot of research has shown a clear connection between depression development and changes in brain structure and function. As a result, the information that is now available strongly supports that brain anatomy may play a moderating role in the co-morbidity of diabetes and depression. As a result, we carried out this research to learn more about this connection, said Dr. Lin.

Changes in the amount of grey matter in the brain have been linked in the past to depression. According to a 2019 study, particular changes in gray-matter volume were linked to lifetime major depressive illness.

Additionally, a study conducted in 2022 discovered that individuals with significant depression, bipolar illness, and schizophrenia spectrum disorders frequently have lower hippocampus grey matter volume.

Examining brain’s grey matter

Dr. Lin and his team gathered information from more than 500,000 UK Biobank individuals between the ages of 40 and 69 for this observational study.

Researchers examined the data and discovered a “significant correlation” between sadness, decreased grey matter volume, and raised levels of HbA1c, or glycosylated hemoglobin.

A quick test called HbA1c determines a person’s blood sugar levels during the previous three months, or glycosylated hemoglobin.

In comparison to study participants with or without diabetes, researchers found that a reduced grey matter volume was associated with depression. This association was particularly pronounced in study participants with prediabetes.

Even if the outcome supports our hypothesis, Dr. Lin stated, “We are still very excited about it.”

Previous studies on the specific brain regions connected to depression have been rather scarce, frequently concentrating on well-established clinical regions such the hippocampus or prefrontal cortex. Contrarily, we were able to more thoroughly analyse and identify probable grey matter regions that may be connected to depression in our study since it made use of MRI data from hundreds of different brain areas,” he said.

Age as a risk factor for increased risk

Furthermore, participants in the study who were 60 years of age or older had the strongest correlation between decreased grey matter volume and depression.

According to Dr. Lin, “This finding has important public health implications, particularly for the neurological health of older individuals.”

In particular, the findings indicate that in older people compared to younger people, the decline in grey matter volume is more pronounced for every one unit increase in HbA1c. The difference can be more than twice as great in some brain regions, according to Dr. Hualiang Lin.

This study shows that we may soon face increased dangers to brain health and mental well-being, he said, “given the global trend of population aging and the rising risk of diabetes.”

What does a normal blood sugar level mean?

Glucose, sometimes referred to as blood sugar, is crucial for numerous bodily processes. It is the body’s main source of energy, to start. And glucose is what “feeds” the brain, keeping it active and maintaining connections amongst its associated nerve cells.

The food you eat, especially carbohydrates like starchy vegetables, whole grains, and fruits, provides the body with blood sugar. Glucose is released into the bloodstream as these nutrients are broken down by the body through the digestive tract.

The pancreas starts to secrete insulin as soon as blood glucose levels increase. To give the body’s cells with the energy they require, insulin aids glucose absorption.

An individual with diabetes or one who is at risk for getting it may have high fasting blood sugar levels:

  • A good fasting blood sugar level is one that is 99 mg/dL or lower.
  • Prediabetes is indicated by a fasting blood sugar level between 100 and 125 mg/dL.
  • One has diabetes if their fasting blood sugar level is 126 mg/dL or greater.

Hyperglycemia, or having too much glucose in the bloodstream, can cause the following symptoms:

Could controlling blood sugar lessen depression?

Dr. Daniel Pompa, a cellular health expert, author of the “Cellular Healing Diet,” and host of a weekly Cellular Healing TV podcast and YouTube show. He stated after reviewing this study that it has long been known that blood sugar levels have a significant impact on brain health. Also, this study only serves to further that understanding.

High glucose levels cause brain inflammation, which lowers cognitive function and emotional control. According to Dr. Daniel Pompa, long-term exposure to elevated glucose levels has been related to altered brain circuits that raise the chance of developing depression.

In those with prediabetes and type 2 diabetes, higher levels of glycosylated hemoglobin (HbA1c) are associated with a reduction in brain capacity. Elevated HbA1c is linked to decreased grey matter sizes in regions including the hippocampus, thalamus, and prefrontal cortex. This is according to several other research that have supported this, Dr. Pompa continued.

As a strategy to treat type 2 diabetes, Dr. Pompa said he would like to see further research on the impact of lifestyle modifications and fasting. It also brain scans to measure these people’s grey matter volume.

In particular, he asked, “Can reducing type 2 diabetes symptoms stop or even reverse the loss of grey matter and lower rates of depression?”

Dr. Matthew J. Freeby, director of the Gonda Diabetes Centre and associate director of diabetes clinical programmes at the David Geffen UCLA School of Medicine, said: “Unfortunately, depression is quite common in people living with diabetes, and there’s not much known as to the connection. For a better understanding of the problem’s causes and potential treatments, more research is urgently needed.

Although this research makes an interesting observation, Dr. Freeby stated that he did not believe we could yet identify physical changes in grey matter volume as the explanation.

REFERENCES:

For Depression medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?cPath=77_478

The Risk of Depression May Rise If You Eat French Fries.

The Risk of Depression May Rise If You Eat French Fries.

Comments 0 Comment

According to a recent study, eating fried meals frequently is associated with greater rates of anxiety and sadness.

According to the study, eating fried foods frequently—especially fried potatoes—increases your risk of developing anxiety and depression by 12% and 7%, respectively.

This, according to experts, is due to a number of factors, such as disruption of the lipid metabolism, an increase in inflammation, and gut disruption.

Try boiling, poaching, or grilling your meal as an alternative to frying it to limit your intake of fried foods.

The two mental illnesses that are most common worldwide are anxiety and depression.

Fried foods make up a large portion of the Western diet and are becoming more popular everywhere. Consuming processed or fried foods, sweet goods, and alcoholic beverages have been related to an increased risk of depression, according to prior research.

Additionally, studies suggest that frying may alter the nutritious makeup of food and release toxic compounds. Acrylamide is produced when carbohydrates are fried, such as potatoes, and it has been connected to neurological problems, metabolic syndrome, and obesity.

Few research have looked into how acrylamide might impact anxiety and depression up until this point. Additional research into this connection may help shape public health initiatives and dietary treatments for mental health issues.

Researchers have recently looked into the relationship between eating fried meals and depression and anxiety. They discovered that eating fried food, particularly fried potatoes, is associated with a higher risk of developing anxiety and depression.

How the research was carried out?

The study, which covered 140,728 participants, found that eating regularly unhealthy fried foods increases one’s risk of anxiety and depression by 12% and 7%, respectively.

The pollutant known as acrylamide found in fried foods, according to the researchers, is “strongly associated” with an increased risk of anxiety and depression.

It has been established that this pollutant causes neuroinflammation and perturbs lipid metabolism, both of which have an impact on mental health.

Even though many who enjoy fried food may be disappointed by these findings, there is a positive aspect to them. We may be able to lower our risk of developing some mood disorders by paying closer attention to what we eat.

Examination of the impact of fried food

The researchers started by looking at data from 140,728 individuals in the UK Biobank. During an average follow-up period of 11.3 years, data on fried food consumption and the prevalence of anxiety and depression were collected.

The researchers found 12,735 cases of depression and 8,294 cases of anxiety towards the end of the study period. Overall, they discovered that compared to non-consumers, those who had more than one dish of fried food daily had a 12% higher risk of anxiety and a 7% higher risk of depression.

Males, younger people, and active smokers were most likely to consume fried food frequently. The researchers next looked into potential mechanisms explaining the association between fried foods and depression and anxiety.

They did this by watching how zebrafish were impacted over time by persistent exposure to acrylamide. They discovered that fish exhibited anxiety- and depression-like behaviour when exposed to low amounts of acrylamide.

Following additional tests, the researchers discovered that acrylamide decreased lipid metabolism, caused neuroinflammation, and decreased the blood-brain barrier’s permeability.

Relationship between food and mood

“As opposed to what is frequently portrayed, the relationship between food and mood is far more nuanced. However, there are undoubtedly dietary habits that seem to offer protection, according to Rohini Bajekal, a nutritionist and board-certified specialist in lifestyle medicine at Plant-Based Health Professionals.

“The results of this study are in line with what we would expect to see and are further confirmation of decades of research showing that fried and unhealthy foods in the typical Western diet increase the risk of common chronic diseases and mental health conditions,” says Rohini.

Fried meals contribute to inflammation in the body, which is linked to symptoms of anxiety and depression. This is one of the reasons why fried foods are linked to greater rates of anxiety and depression.

A 2017 study called the SMILES Trial, which Megan Hilbert, a registered dietitian at Top Nutrition Coaching, cites, shows that mental health outcomes were significantly better when a control group adhered to a diet rich in anti-inflammatory foods for 12 weeks.

Inflammation effects on body and brain

Because fried foods contain molecules called advanced glycation end products that stick to tissue, harm it, and promote inflammation, Hilbert claims that a diet high in fried foods contributes to neuroinflammation, or inflammation in the brain.

Although further research is needed on this subject, Hilbert points out that it is hypothesised that inflammation may reduce the release of dopamine and weaken the regions of the brain connected to rewards.

Fried meals also frequently lack fibre, phytonutrients, and healthy fats, all of which have been found to improve brain function. Your digestive system may then be impacted by this.

According to Hilbert, “a deficiency in these compounds can result in a breakdown in the communication between the gut and the brain.” The production of these neurotransmitters is thought to be influenced by abnormalities in our gut microbiota because upwards of 90 to 95% of our serotonin is created there. As a result, it is thought that these imbalances have a negative impact on our mood.

The primary toxin that may be harming mental health, according to the study’s authors, is acrylamide.

Hilbert says that when certain starchy foods are roasted, fried, or baked at high temperatures, a chemical called acrylamide can naturally occur. “Studies have shown that acrylamide is carcinogenic to animals and may be carcinogenic to humans.”

Hilbert emphasises the need of keeping in mind that the acrylamide concentrations utilised in animal experiments were at extremely high dosages.

Foods that promote mental wellness

We discussed whether there are any foods that can help or prevent depression and anxiety with Dr. Kelly Johnson-Arbor, Medical Toxicologist, Co-Medical Director, and Interim Executive Director at the National Capital Poison Centre, who was not involved in the study.

According to Dr. Johnson-Arbor, “There are no specific foods that have been proven to treat or prevent depression or anxiety.” However, compared to the “Western” diet, the Mediterranean diet, which emphasizes the consumption of fruits, vegetables, legumes, and whole grains, is linked to lower levels of C-reactive protein.

Lower levels of C-reactive protein may help prevent the onset of depression, anxiety, and other illnesses impacted by inflammation because they are linked to inflammation, the author continued.

Consequences

We discussed the ramifications of the study with Dr. Spiegel. He stated:

The results of this study suggest that eating more fried food, particularly potatoes, raises the level of acrylamides in the blood. Depression and anxiety may be brought on by the greater levels of this toxin, which affects how different types of nerve cells in the brain function. Among younger people, the effects are more obvious.

The key takeaway is to limit your intake of fried foods like French fries, hash browns, bacon, and others to special occasions. No more than one dish should be consumed per month, in my opinion. Consuming alcohol frequently may increase anxiety and depression as well as cause a number of other health issues, he said.

REFERENCES:

For Depression medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?therapy=6

Talk therapy for depression may lower heart disease risk.

Talk therapy for depression may lower heart disease risk.

Comments 0 Comment

The benefits of talk therapy may go beyond the treatment of mental disease, however, they are crucial in the management of depression. Researchers are still trying to figure out how depression and cardiovascular disease are related.

According to a study, those with depression who had relief from their symptoms following psychotherapy also had a lower risk of developing cardiovascular disease.

One of the most prevalent mental illnesses, depression can have negative effects on other aspects of health. Researchers are still trying to figure out how depression treatment affects the outcomes of cardiovascular disease and how the two are related to one another.

In a recent study, published in the European Heart Journal, it was investigated how the use of psychotherapies to treat depression affected the progression of cardiovascular disease.

The researchers discovered that people who experienced reduced depression following psychotherapy also experienced a decreased risk for developing new cardiovascular illnesses, coronary heart disease, stroke, and all-cause death.

Talk Therapy

Mental health experts interact with their patients through talk therapy, sometimes called psychotherapy. Talk therapy is meant to aid in the identification of problems that are generating emotional pain.

Everybody experiences emotional ups and downs. Some people’s issues are transient, therefore no therapy is required. However, for some people, attending talk therapy can significantly improve their mood and even alter their attitude on life.

It could be appropriate to think about talk therapy if you’re dealing with a medical condition, losing a loved one, or experiencing anxiety, stress, or depression.

For some people, talk therapy can provide a secure setting to talk about feelings and emotions brought on by everyday stressors, a medical condition, interpersonal conflict, bereavement, or the effects of a particular event.

Other people may experience the same problems in a complex way, leading to a diagnosis of a mental illness like depression or anxiety.

Once the problems are located, a therapist will work with you to comprehend how these pressures affect your life and will assist you come up with solutions and techniques to lessen the severity of the symptoms.

A talk therapy session typically lasts for 50 minutes to an hour. The frequency and duration of therapy sessions depend on the severity of your symptoms and your treatment plan.

You might anticipate going to counselling once a week at first. Attending weekly appointments provides you the chance to get to know your therapist and become accustomed to the process, even though it may feel like a big commitment.

As you learn coping mechanisms and start to exhibit signs of progress, the number of meetings may increase to twice a month.

Talk therapy is used to treat depression.

A frequent mental ailment that affects people all around the world is depression. It can be crippling and challenging to control. Depression and other health issues can have complicated relationships.

For instance, those who have certain chronic conditions may be more susceptible to depression. People with depression may also be more susceptible to other health issues like pain and type 2 diabetes.

Individuals’ mental and physical health depend on receiving prompt treatment for depression.

One often-used element of depression treatment is psychotherapy. Talk therapy is a frequent abbreviation for psychotherapy. There are various forms of psychotherapy, but they can all concentrate on addressing issues, spotting negative thought patterns, and controlling actions and emotions.

Talk therapy is used to treat depression, according to Dr. Sarah-Nicole Bostan, a clinical health psychologist and director of behaviour change strategy at Signos who was not involved in the study.

Psychotherapy is frequently suggested as a first-line treatment for depression because of its well-known efficacy and minimal to no side effects, except for brief discomfort during therapy. One of the most successful evidence-based forms of treatment for depression is cognitive behavior therapy (CBT), which includes behavioral activation. In CBT, patients learn more constructive ways to view themselves as well as how to put new behaviors and routines into practice to help them feel better.

“Effectiveness of therapy can be measured throughout treatment through validated assessments, but at a bare minimum should be assessed at the beginning and end of a course of treatment,” she said. The indirect effects of psychotherapy on other aspects of health are still a subject of research.

Psychotherapy reduces the risk of CVD

Heart and blood vessel issues fall under the broad area of cardiovascular disease (CVD). Heart attack, stroke, and heart failure are a few examples of cardiovascular ailments.

This retrospective cohort study’s researchers sought to comprehend the connection between the risk for cardiovascular disease and the efficacy of treating depression.

In their investigation, researchers used 636,955 participants. Each participant had finished a term of treatment and met certain threshold requirements for depression. Additionally, none of the participants in the Improving Access to Psychological Therapy programme had cardiovascular illness prior to utilising it.

Researchers checked in on individuals on average three years later to see how often cardiovascular events and all-cause deaths occurred.

Researchers discovered that the greatest benefit was experienced by those whose depression improved after psychotherapy. According to what they discovered, “those whose depression symptoms improved after therapy were 12% less likely to experience a cardiovascular event than those who did not.”

They also discovered a link between reduced risk of coronary artery disease, stroke, and all-cause mortality and improved depression following medication. People under the age of 60 had a larger reduced risk of cardiovascular disease than people beyond the age of 60.

Study restrictions

This study contributes to our understanding of the effects of psychotherapy on other aspects of health. To have a deeper grasp in this area, more research is required.

There were some important restrictions on the study. First, participant self-reporting is used in the assessments of improved depression, which has several drawbacks. Examining every item that might have helped with the improvement of depressed symptoms is also difficult.

Additionally, the study is unable to demonstrate that treating depression lowers the chance of developing cardiovascular disease. It’s likely that individuals made further lifestyle adjustments that decreased risk.

Researchers are aware that reverse causality is a possibility, and the findings of the study cannot be applied to those who do not seek treatment for depression. The study had a short follow-up period as well, so future research may use longer time periods.

Finally, data on a number of possible confounders, such as participant social support, alcohol consumption, or tobacco use, were lacking. These unaccounted-for variables might have affected the effectiveness of depression treatment and cardiovascular risk.

Next steps in research

Overall, the research shows that psychotherapy has a big impact on other health outcomes.

Dr. Sarah-Nicole Bostan said, “This research confirms what we’ve known for quite some time, which is that even a small number of sessions lasting anywhere between 30 minutes and an hour over a few short months can not only significantly ameliorate depression symptoms, but can also set someone on a healthier trajectory for years to come by providing patients with the tools to address their future stressors.”

More investigation is required in this field, but the study shows the value of psychological therapy, according to Celine El Baou.

“This study is a preliminary step towards understanding this link. To establish causation or comprehend specific behavioral or biological factors, more study is required. It does, however, highlight how crucial it is to ensure that psychological therapies are widely available, she added.

REFERENCES:

For Heart disease medications that have been suggested by doctors worldwide are available here https://mygenericpharmacy.com/index.php?cPath=77_99

Amino acid: A key in improving depression treatment.

Amino acid: A key in improving depression treatment.

Comments 0 Comment

The role of a receptor called GPR158 in depression was discovered by researchers at the University of Florida over the course of a 15-year investigation.

In a study, mice who had their GPR158 expression suppressed were less likely to experience stress-related sadness. The structure of GPR158 was discovered by the researchers, and this allowed them to connect it to the amino acid glycine.

Many drugs exist to treat depression, which affects millions of people, but it can be challenging to select the proper one.

Scientists at the Herbert Wertheim UF Scripps Center for Biomedical Innovation and Technology uncovered a finding that revealed how an amino acid is related to depression while studying neurotransmitters.

The revelation was the result of more than ten years of investigation into the functioning of brain cell signalling. Although though discovering a connection to depression was not the original aim of the study, the researchers are enthusiastic about their findings since they potentially influence how depression will be treated in the future.

Depression

In the United States, depression affects over 21 million adults each year, according to the National Institute of Mental Health (NIMH). The COVID-19 pandemic saw a sharp increase in depression rates, which have since persisted and are now a serious issue. Rates among children under 18 are also rising.

While some people suffer situational depression as a result of external factors (such losing a loved one), other people struggle with depression for extended periods of time and it can progress into Major Depressive Disorder.

The NIMH includes the following indications and symptoms of depression among others:

  • recurring sense of sadness
  • feeling a sense of emptiness
  • experiencing a decline in energy or weariness
  • having difficulties sleeping
  • feeling suicidal thoughts

Individuals who have persistent depressive symptoms may require medical attention. To treat the symptoms of depression, doctors may give drugs, offer treatment, or advise lifestyle modifications.

Tricyclic antidepressants (like imipramine or amitriptyline), selective serotonin reuptake inhibitors (like sertraline or escitalopram), and serotonin-norepinephrine reuptake inhibitors are a few examples of depression drugs (such as duloxetine or venlafaxine).

Those on antidepressants should consult with their healthcare providers frequently and inform them of any suicidal thoughts because these medications can have negative effects, including thoughts of suicide.

Brain cell receptors and depression

The goal of the writers was not to find a connection to depression at first. 15 years ago, they set out to study how brain cell receptors function, and they have achieved that goal.

Prof. Kirill Martemyanov, one of the study’s authors, stated: “Fifteen years ago we discovered a binding partner for proteins we were interested in, which led us to this new receptor.” “We’ve been unravelling this for a while now.”

Professor Martemyanov teaches at the University of Florida Health’s Department of Neurology.

The next several years saw the discovery of the GPR158 receptor by the researchers. In experiments with mice, they discovered that a mouse would be more resistant to stress-induced depression if that receptor was suppressed in the body.

Amino acid treating depression

A 2017 assessment of the literature concluded that glycine is “one of the most significant and straightforward non-essential amino acids in humans, animals, and many mammals.”

The scientists were shocked to learn that GPR158 was an inhibitor when they realised that glycine was the signal’s sender and that it binds to glycine; they changed its name to mGlyR as a result (metabotropic glycine receptor).

The identification of mGlyR should pave the way for fresh investigation into the management of depression, which Prof. Martemyanov intends to do.

Expert responses

Medical News Today spoke with Dr. Simon Faynboym, a physician who has experience working with the American Psychiatric Association.

Dr. Faynboym stated that the findings “essentially shows that glycine can interact with the GPR158 system.” The researchers demonstrate a biochemical mechanism, but the most significant lesson is that this process may represent the link between glycine and taurine’s potential antidepressant qualities.

Currently serving as a delegate to the California Medical Association is Dr. Faynboym. Dr. Faynboym acknowledged the significance of the study but also emphasized that depression is “very complex” and that other neurotransmitters are involved.

Dr. Faynboym remarked that there are numerous factors at play while dealing with depression. “Depression involves several neuronal networks, various neurotransmitters leaving and entering neurons at various rates, and impacts all areas of the brain. Because of the dynamics of the brain, one of the most complicated medical specialisations is mental health.

Dr. Faynboym emphasised the significance of this kind of research in light of this. Since they provide another glimpse behind the curtain of the big unknown that is the brain, research pieces like this one advance the science of psychiatry.

A psychiatrist from Palm Beach Gardens, Florida named Dr. Jessica Turner also discussed the study’s findings.

The medial prefrontal cortex is a well-known brain region associated with depression, and this work suggests targeting a specific receptor there, according to Dr. Turner. “We anticipate providing better, more efficient alleviation for people who are depressed in the future with more focused treatments.”

REFERENCES:

For more details, kindly visit below.

Depression may increase stroke risk, and stroke recovery.

Depression may increase stroke risk, and stroke recovery.

Comments 0 Comment

The World Health Organization (WHO) claims that depression is the main cause of disability in the globe. At least 5% of adults are affected, with more women than males reporting symptoms of depression.

Symptomatic depressed individuals are more likely to have a stroke, and their recovery from one is frequently more challenging, according to a multi-national study.

According to this study, persons with depressive symptoms had a 46% higher risk of having a stroke than those without such symptoms.

Over 280 million people worldwide suffer from depression. 10.4% of women in the United States experience depression, which is almost twice as frequent in women as it is in males, according to the Centers for Disease Control and Prevention (CDC).

Psychological signs of depression include a continuously downbeat attitude, a sense of worthlessness, a loss of interest in enjoyable pursuits, trouble concentrating, and even suicidal thoughts.

In addition, physical symptoms including exhaustion, an inability to eat, headaches, chronic pain, and digestive problems may be brought on by sadness.

Moreover, depression and cardiovascular disease (CVD) have been connected in research; one studyTrusted Source found that individuals with coronary heart disease who were depressed had an increased risk of dying.

An international study that was just published in Neurology discovered that those who experience depressed symptoms had a higher chance of both ischemic and hemorrhagic stroke, as well as a worse recovery after a stroke.

What is a stroke?

A stroke happens when a blood vessel in the brain bursts and bleeds or when the blood supply to the brain is cut off. Blood and oxygen cannot reach the brain’s tissues because of the rupture or obstruction.

Stroke is a primary cause of death in the US, according to the Centers for Disease Control and Prevention (CDC). More than 795,000 Americans experience a stroke each year. Brain tissue and cells are damaged and start to die within minutes of being oxygen-deprived.

Strokes often come in three different forms:

  • Temporary ischemia. A blood clot causes a transient ischemic attack (TIA), which normally resolves on its own.
  • Ischemic stroke. It involves an obstruction in the artery brought on by a clot or plaque. The signs and problems of an ischemic stroke may persist permanently or linger longer than those of a TIA.
  • Hemorrhagic stroke. A blood vessel that seeps into the brain either bursts or leaks, which is the source of the condition.

Strokes are often fatal. According to the American Heart Association (AHA), there were 37.6 age-adjusted deaths for every 100,000 stroke diagnosis in 2017. This fatality rate is 13.6% lower than it was in 2007 thanks to medical advances in the treatment of strokes.

What is a Depression?

Depression is basically a common but serious mental disorder, medically termed as Major Depressive Disorder which negatively affects a person’s way of thinking, how the person feels and behaves. This mental disorder is different from mood fluctuations. In addition to causing emotional and physical problems, it can also make it difficult for you to function at work and at home.

Despite the existence of effective treatments for mental disorders, more than 75% of people in low- and middle-income countries do not receive any treatment. There are several barriers to effective mental health care, including a lack of resources, a lack of trained health-care providers, and social stigma associated with mental illness. People with depression in countries of all income levels are frequently misdiagnosed and prescribed antidepressants even when they do not have the disorder.

Details from the stroke and depression study

In total, 26,877 adult study participants from 32 nations in Europe, Asia, North and South America, the Middle East, and Africa participated in the study.

As a neuroscientist and associate professor at the University of Nevada, Las Vegas, Dustin Hines, PhD, stated to Healthline, “This work represents a tremendous achievement in the knowledge of both stroke and depression. “When considered in light of how variable the group of patients suffering from depression is, the statistically significant difference between responders who reported depression before the stroke is even more impressive.”

According to research, 13% of the 13,000 participants who experienced a stroke also had depressive symptoms. Depression was prevalent among those who had no stroke, at 14%.

Increased stroke risk

When compared to people who did not have a stroke (14%), those who had one were more likely to develop depressive symptoms (18%). Those who admitted to having “given up on improving their lives” were at higher risk of suffering a stroke.

Those who had symptoms of depression had a 46% higher risk of stroke than those who did not experience such symptoms, even after the researchers made adjustments for age, sex, education, physical activity, and other lifestyle factors.

The correlation between depressive symptoms and stroke was discovered to be constant across all country economic levels. Stroke risk was increased in people with four or more symptoms of depression than in those with fewer symptoms.

In response to this research, Dr. Benesch stated that “this link between more severe depression and stroke risk is undoubtedly worthy of further examination and may be clinically meaningful.”

“One analogy would be that we are aware that lung cancer is brought on by smoking. We also know that daily smokers have a higher risk of developing lung cancer than smokers who only smoke sometimes (once every six months). Hence, he continued, “it would seem that there is a dose-response relationship.

The study also discovered that although strokes in those with depressive symptoms were not more severe, their outcomes one month after the stroke were worse.

Depression and CVD or stroke

Depression and heart disease and stroke have already been associated in a number of studies.

A 2011 meta-analysis of 17 research revealed that depressive disorders considerably increased the probability of having a stroke, and that the increase was likely independent of other risk factors like diabetes or hypertension. This study was unable to establish a causal relationship, nevertheless.

The same year, a bigger meta-analysis that examined 28 prospective cohort studies came to the conclusion that depression is prospectively linked to a considerably higher chance of having a stroke.

In 2020, a different study discovered that persons who had depressive symptoms had a higher risk of developing heart disease or having a stroke later on.

Despite the association’s modest size, it was nonetheless noticeable among those who did not exhibit depressive disorder-like symptoms.

How depression affects people who’ve had a stroke?

“Depression is not unusual for people following a stroke, I’ve discovered in my experience with stroke patients,” Waichler continued. “Both the stroke sufferer and their loved ones may suffer greatly from the loss of independence, physical limitations, restrictions on one’s capacity for self-care, and probable cognitive and communication problems. A person’s willingness or the requisite amount of resolve to fully engage in the recovery process may be adversely affected by depression. The outcome could be worse as a result and the stroke recovery could be hindered.

The biggest unsolved question in the study, according to Karen Sullivan, PhD, a neuropsychologist and the creator of the I Care For Your Brain website, is “What is it about depression particularly that enhances the risk of stroke?”

“The range of depressive symptoms includes the cognitive, emotional, and physical. Knowing which particular factors were most closely associated to stroke risk would be really beneficial, Sullivan told Healthline. “Even though the study filtered out typical characteristics linked with depression that could confound the results like low physical activity, there are lots of additional lifestyle risks that go along with depression that could have affected the results including bad diet, low socialising, not enough cognitive stimulation, inflammation, [and] noncompliance with medical guidance,” the study’s authors write.

According to Sullivan, the most significant lesson that patients, healthcare professionals, and the general public should learn from this study is the value of depression screening.

In addition to enhancing a person’s general health and quality of life, she added that recent research suggests that treating depression also lowers the chance of stroke. Large-scale, long-term studies are required, and it is important to understand whether effective therapy lowers the risk of stroke in order to demonstrate a more causal link between depression and stroke.

The apparent next step, according to Hines, is to search for widespread biomarkers that may be connected to metabolic issues and attempt to assist patients before they experience a stroke.

REFERENCES:

For more details, kindly visit below.

Explore the easy hacks to deal with depression.

Explore the easy hacks to deal with depression.

Comments 0 Comment

As sneaky as it is unpredictable, depression may be. You could be surprised by it at any time. even when everything appears to be going according to plan and when everything is “wonderful.”

You might be asking yourself, “How can I feel so horrible when I have so much to be grateful for?” while you try to make sense of this. Worst yet, “I have no business feeling depressed,” Such ideas are not constructive. These just serve to reinforce guilt feelings, which are depression’s best buddy and partner.

Your relationships, your job, and your entire feeling of self-worth can all be affected by clinical depression. It has a powerful punch. Fortunately, there are resources out there that can aid in your resistance.

Preventative care is of course the most significant (therapy, a positive support system, getting enough sleep and exercise, etc.). But, the following are some spot-on, urgent steps you can take if you find yourself in the middle of a depressive episode. All of these “tools” won’t be able to cure depression, but they might at least help clear things up a little.

Symptoms of depression

In a depressive episode, the individual experiences significant difficulties in personal, family, social, educational, occupational, and/or other important areas. The symptoms generally differs in terms of severity and natured which is based on individual occupation, gender, and age group. Depression symptoms can vary from mild to severe and can include:

  • Changes in appetite
  • Loss of energy or increased fatigue
  • Increase in purposeless physical activity or slowed movements or speech
  • weight loss or weight gain
  • Trouble sleeping or sleeping too much
  • Feeling sad or having a depressed mood
  • Feeling worthless or guilty
  • Difficulty thinking, concentrating or making decisions
  • Thoughts of death or suicide
  • Loss of interest or pleasure in activities once enjoyed

Furthermore, medical conditions such as thyroid problems, brain tumors, and vitamin deficiencies can mimic depression symptoms, so it is important to rule out general medical causes.

Hacks to relieve depression

Activate your body.

Moving your body is the fastest technique to combat depression feelings right now. Of course, exercising may be the last thing you feel like doing when you’re depressed. It need not be difficult, though; any kind of physical exercise will do.

Just performing 20 jumping jacks or shaking your body for a minute or more can have an impact. Our thoughts and bodies are intertwined; if we let our bodies take the lead, the mind will probably follow.

Answer the phone.

Dial a number. a buddy. an associate. With one exception, any kind of social connection can be extremely therapeutic. Make sure the individual you are connected with is a positive support who feeds you rather than drains you.

If you are unable to phone, you can still text someone to feel connected. If you have no one to contact or text, go online and pick one of the many support groups or chat rooms to meet people going through similar experiences to you. Human connection has the ability to heal.

Determine possible triggers.

Even though a depressed episode can appear to occur suddenly and without “good reason,” there usually is an outside trigger. It could be a difficult conversation or experience that you haven’t yet processed, or it could be a self-defeating mindset, which is more harder to recognise.

You can respond, “But nothing happened, and I wasn’t even thinking about anything at the time,” in response to this. The second is impossible. We are constantly thinking. Our thoughts never go away, whether we are debating the meaning of existence or choosing which shoes to wear.

Negative ideas might blend in with the background. Like the sirens you hear so frequently, you stop noticing them. Worst-case scenarios involve these pessimistic thoughts developing into strongly held self-beliefs. For instance, skewed, unfavourable thoughts may surface if you failed a test or lost your job, such as “I failed because I’m not smart enough” or “I’ll never find another job again.” It doesn’t matter what you believe or feel, it still might not be real. It is our responsibility to recognise these thoughts before they take control and to resist them.

Reject the provoking thought.

Lies are one of depression’s greatest strengths. Never trust them.

Once the negative concept has been located, question its veracity. Ask yourself: How do you know that, for instance, when you tell yourself, “I’ll never find another work again”? The future cannot be predicted. Instead, in response to the statement, “I’m not smart enough,” you might provide evidence to the contrary, such as a list of all the times you performed well or your accomplishments to date.

Also, avoid generalising. Simply because you lost one job or failed one test does not mean that you will never find another one or pass another test. Whatever depression tells you, ignore it!

Remain in the current moment.

When depression has you in its tight grip, it might be difficult to think clearly. The prefrontal cortex, a better developed region of the brain that governs cognitive processes like rational thought, can frequently lose control to the limbic system, which governs emotions.

Here, mindfulness can be useful. This does not imply that you must sit and practise meditation for 20 minutes (although practising meditation is one of the best ways to cultivate mindfulness). Catching a negative idea and immediately changing your attention to something physical in the present, like your breath or the noises or odours around you, sometimes be all it takes. Being aware is more than just a trendy concept; it will benefit you all your life.

Take refuge in a good movie.

We all need to occasionally step outside of our thoughts. Of course, in a non-destructive manner. One of the things to do is to watch a fantastic movie. Avoid tearjerkers and instead pick a comedy or at least an upbeat movie. Only a few examples of comedic and/or lighter movies that you can add to your toolkit for battling sadness are provided below.

REFERENCES:

  • https://www.psychologytoday.com/us/blog/nurturing-self-compassion/202006/6-depression-hacks
  • https://www.webmd.com/depression/ss/slideshow-easy-habits-improve-mental-health?
  • https://www.wondermind.com/article/how-to-deal-with-depression/
  • https://www.blurtitout.org/2016/06/14/managing-depression-hacks-hints-difficult-days/?doing_wp_cron=1676625387.6235940456390380859375

For more details, kindly visit below.

Challenges of Insomnia in an individual’s life.

Challenges of Insomnia in an individual’s life.

Comments 0 Comment

What is Insomnia?

Millions of individuals all around the world constantly experience insomnia, a sleep problem. A person with insomnia has trouble getting to sleep and staying asleep. Depending on their age, adults, according to the Centers for Disease Control and Prevention (CDC), require between 7-9 hours of sleep every night.

According to research, 25% of Americans report having insomnia each year, although 75% of these people do not go on to have a chronic condition. Short-term insomnia can cause daytime weariness, attention problems, and other issues. Long-term, it could raise the risk of contracting certain illnesses.

An insomniac has trouble getting to sleep or staying asleep. They might often get up too early.

This may result in problems like:

  • Lethargy and tiredness during the day
  • an overall sense of being physically and mentally ill
  • anxiety, impatience, and changes in mood

Additionally, the aforementioned problems may be causes, effects, or both of insomnia.

In addition, chronic illnesses like the following may be influenced by insomnia:

  • obesity
  • diabetes
  • a cardiovascular condition
  • depression

It can also impair a person’s effectiveness at work and school and restrict their capacity to carry out daily tasks.

Causes of insomnia

There are many different medical and psychological causes of insomnia. Frequently, a transient issue, such as transient stress, is the root reason. In certain other cases, an underlying medical problem is the cause of the sleeplessness. Typical causes include

  • dealing with any additional adjustments to the body’s internal clock, such as jet lag, shift changes at work, or other circumstances
  • If it prevents sleep, it could be the bed being uncomfortable, the room being too hot, cold, or noisy, or taking care of a family member.
  • getting insufficient exercise
  • experiencing nightmares or nocturnal terrors
  • utilising drugs for fun, such cocaine or ecstasy

Some people experience insomnia as a result of stress or a mental health condition. A person might be going through:

Other medical disorders that may interfere with sleep include:

  • Irritable bowel syndrome
  • excessive thyroid activity
  • nap apnea
  • GERD, also known as gastroesophageal reflux disease
  • COPD, also referred to as chronic obstructive pulmonary disease
  • chronic pain

Sleeping problems are frequently caused by signs of various health problems or by changes in the natural world. For instance, hormonal changes during menopause might cause night sweats, which can keep you awake. Sleep patterns are disturbed or altered in patients with Alzheimer’s disease due to abnormalities in the brain.

Additionally, some people experience fatal familial insomnia, a rare genetic disease that makes it difficult to fall asleep and may possibly be fatal.

Symptoms of insomnia

In addition to interrupted sleep, insomnia can result in various problems, including:

  • daytime drowsiness or weariness
  • irritation, sadness, or worry
  • signs of the digestive system
  • low dynamism or motivation
  • insufficient focus and attention
  • an absence of coordination that results in mistakes or accidents
  • anxiousness or fear about sleeping
  • using sleeping pills or booze
  • stress headaches
  • having issues working, learning, or socialising

According to experts, sleep deprivation is a major contributing factor in car accidents.

Types of insomnia

Depending on the duration, insomnia can be categorised as follows:

  • A short-term issue is acute, brief sleeplessness.
  • It may take months or years to overcome chronic insomnia.

The causes are also classified by doctors:

  • A problem in and of itself is primary insomnia.
  • Secondary insomnia is brought on by another medical condition.

They also categorise it according to severity:

  • Mild insomnia is characterised by a lack of sleep that causes fatigue.
  • Daily functioning may be impacted by moderate insomnia.
  • Life is significantly affected by severe sleeplessness.

When determining the kind of insomnia, doctors also take into account additional variables, such as whether the patient regularly wakes up too early or experiences difficulty:

  • a sound slumber
  • remaining in bed
  • getting quality sleep

Treatments

Depending on the underlying issue and the type of insomnia, several approaches may be best, however some possibilities include:

  • counselling
  • CBT stands for cognitive behavioural therapy.
  • medicines on prescription
  • several over-the-counter sleep aids that can be purchased online
  • Melatonin, which can be purchased online as well

Melatonin may promote sleep, however there isn’t enough convincing evidence to support this claim.

REFERENCES:

For more details, kindly visit below.

Undenieable causes and symptoms of Diabetes you must know.

Undenieable causes and symptoms of Diabetes you must know.

Comments 1 comment

What is diabetes?

Diabetes mellitus, also known as just diabetes, is a metabolic condition that raises blood sugar levels. Insulin is a hormone that transports sugar from the blood into your cells where it can be stored or utilised as fuel. When you have diabetes, your body can’t use the insulin it does make or doesn’t produce enough of it.

Diabetes-related high blood sugar left untreated can harm your kidneys, nerves, eyes, and other organs. However, you can safeguard your health by learning about diabetes and taking measures to prevent or control it.

Types of diabetes

There are several varieties of diabetes:

  • Type 1: Diabetes type 1 is an autoimmune condition. The immune system targets and kills insulin-producing cells in the pancreas. Uncertainty surrounds the attack’s origin.
  • Type 2: When your body gets resistant to insulin, type 2 diabetes develops and blood sugar levels rise. About 90% to 95%Trusted Source of people with diabetes have type 2, making it the most prevalent kind.
  • Type 1.5: Latent autoimmune diabetes in adulthood is another name for type 1.5 diabetes (LADA). Like type 2 diabetes, it develops gradually during maturity. LADA is an autoimmune condition that cannot be controlled by a healthy diet or way of living.
  • Diabetes gestational: Diabetes gestational is excessive blood sugar when pregnant. This form of diabetes is brought on by substances the placenta secretes that block insulin.

Despite having a similar name to diabetes mellitus, the uncommon illness known as diabetes insipidus is unrelated. Your kidneys are removed from your body too much fluid in a separate ailment. Each kind of diabetes has specific symptoms, underlying conditions, and therapies.

Prediabetes

When your blood sugar is higher than normal but not high enough to be diagnosed with type 2 diabetes, the condition is known as prediabetes. It happens when your body’s cells don’t react to insulin as it should. Later on, type 2 diabetes may result from this.

According to experts, more than one in three Americans have prediabetes, but more than 80% of those individuals are completely unaware of their condition.

Symptoms of diabetes

The onset of diabetes is accompanied by blood sugar increases.

General symptoms

The symptoms of kinds 1, 2, and 1.5 (LADA) are identical, however they manifest more quickly than those of types 2 and 1.5. Type 2 usually has a slower onset. This diabetes is more likely to cause tingling nerves and slow-healing wounds.

Type 1 in particular, if untreated, can result in diabetic ketoacidosis. At this point, the body’s level of ketones is harmful. Although less typical in other forms of diabetes, it is nevertheless conceivable.

Diabetes’s typical signs and symptoms include:

  • increased appetite
  • heightened thirst
  • slim down
  • excessive urination
  • hazy vision
  • extreme exhaustion
  • not-healing wounds

Men’s symptoms

Men with diabetes may have the following in addition to the typical symptoms:

Women’s symptoms

Diabetes symptoms in women might include:

Gestational diabetes

The majority of women who develop gestational diabetes show no symptoms. When doing a routine oral glucose tolerance test or blood sugar test, which is often done between the 24th and 28th week of pregnancy, medical professionals frequently find the issue.

A person with gestational diabetes may, in extremely rare circumstances, also feel increased thirst or urination.

Diabetes symptoms might be so subtle that they are first difficult to identify. Discover the symptoms that call for a visit to the doctor.

Causes of diabetes

Each form of diabetes has a unique set of reasons.

Diabetes type 1

Type 1 diabetes has an unknown specific cause, according to doctors. The immune system wrongly targets and kills insulin-producing beta cells in the pancreas for some unknown cause.

Some people may be affected by their genes. Additionally, a virus may trigger an immune system attack.

Diabetes type 2

The cause of type 2 diabetes is a result of both hereditary and environmental factors. Your risk is further increased if you are overweight or obese. The effects of insulin on your blood sugar are resisted by your cells more when you are overweight, especially in the abdomen.

Families are prone to this condition. Family members have genes that increase their risk of type 2 diabetes and obesity.

Diabetes of type 1.5

When your own antibodies attack your pancreas, you have type 1.5 autoimmunity. like kind 1. Although additional research is required, it might be inherited.

Gestational diabetes

Hormonal changes during pregnancy are the cause of gestational diabetes. The placenta secretes hormones that reduce the sensitivity of a pregnant person’s cells to the effects of insulin. Pregnancy-related elevated blood sugar can result from this.

Gestational diabetes is more likely to develop in people who are overweight before becoming pregnant or who put on too much weight while pregnant.

Diabetes complications

Your body’s organs and tissues are harmed by high blood sugar. Your risk of complications increases as your blood sugar level rises and as you live with it for a longer period of time.

Diabetes-related complications include:

  • stroke, heart attack, and heart disease
  • neuropathy
  • nephropathy
  • Retinopathy and reduced eyesight
  • loss of hearing
  • harm to the feet, such as infections and unhealed wounds
  • skin problems include fungal and bacterial infections
  • depression
  • dementia

Gestational diabetes

Gestational diabetes that is not treated might result in issues for both the mother and the unborn child. Baby-related complications can take the following forms:

  • preterm delivery
  • higher-than-average birth weight
  • a later-life increase in the risk of type 2 diabetes
  • low blood glucose
  • jaundice
  • stillbirth

A woman who has gestational diabetes during pregnancy runs the risk of getting type 2 diabetes or high blood pressure (preeclampsia). You can also need a C-section, often known as a caesarean delivery. Future pregnancies also have a higher risk of developing gestational diabetes.

Although diabetes can cause major medical issues, you can manage the disease with medication and a change in lifestyle.

REFERENCES:

For more details, kindly visit below.

Remedies to overcome side effects of contraceptive pills.

Remedies to overcome side effects of contraceptive pills.

Comments 0 Comment

Contraceptive(Birth control) pills

When taken consistently each day, Contraceptive tablets are one method of birth control that is 99% effective at preventing pregnancy. The pill has hormones that control menstruation, reduce the risk of ovarian and uterine cancer, cure endometriosis, and improve acne.

How does the birth control pill work?

Birth control pill hormones inhibit pregnancy by:

  • ovulation suppression or reduction the release of an egg from an ovary.
  • cervical mucus is thickened to prevent sperm from reaching the uterus.
  • reducing the likelihood that a fertilised egg will attach through thinned uterine lining.

Side effects to taking Contraceptive pill

Starting the pill can cause adverse drug reactions in some women. After a couple of months, these adverse effects frequently get better. In case you suffer any side effects, let your healthcare practitioner know. Changing to a different brand that doesn’t cause issues can be an option for you. However, especially when beginning a new pill regimen, merely waiting out the symptoms for a few cycles frequently helps relieve many of the symptoms. Possible negative effects include:

  • breast soreness or tenderness.
  • Headaches.
  • Easily irritated or depressed.
  • Nausea.
  • In between periods spotting (abnormal menstruation).
  • acne
  • bleeding or spotting between periods
  • bloating
  • blood pressure above your usual range
  • depression
  • fatigue
  • feeling dizzy
  • fluid retention
  • headache
  • increased appetite
  • insomnia
  • melasma (dark patches on the face)
  • mood swings
  • vomiting
  • weight gain

Remedies to overcome side effects.

The tablet depletes nutrition, increases inflammation, can result in thyroid and adrenal dysfunction, causes insulin dysregulation, and alters gut health, in addition to raising worries about stroke, clots, and heart attacks.

But if you’re not ready to stop taking the pill, don’t freak out. The following techniques will help you support your body and reduce adverse effects:

Maintain a hormone balance.

There are many other hormones, such as thyroid, insulin, and cortisol, that need your assistance while the pill is suppressing your natural sex hormones. The severity of the pill’s negative effects can be greatly influenced by what you consume. Estrogen and other hormones can become out of balance with diets high in sugar, refined carbs, alcohol, nonorganic meat, and conventional dairy products.

These abnormalities are further exacerbated by stress, toxins in the environment, and chemicals that affect hormones. Cut back on these problematic foods. To balance your hormones and lessen the side effects that birth control can cause, increase your intake of vegetables, healthy fats, and fibre. To supplement nutrients and support your body while taking pills, think about adding seed cycling to your routine.

Reduce inflammation

According to studies, those who use oral contraceptives have higher levels of the inflammatory marker C-reactive protein (CRP), which can increase the risk of heart disease, than people who don’t take the pill. Your mood will be lifted, cramps will go away, and you’ll feel less tired and back discomfort. Consume a diet high in anti-inflammatory fats that regulate hormones, such as omega-3 fatty acids, which can be found in foods like wild-caught fish and flaxseeds. Consider using curcumin and fish oil as anti-inflammatory foods, and sprinkle turmeric anywhere you can.

Organize your stress.

According to studies, women on the pill have dysregulated HPA-axis (hypothalamic-pituitary-adrenal axis), which results in excessive cortisol secretion. The importance of managing your stress increases while you’re taking medication. Whichever method works best for you should be used. There are many powerful ways to take care of yourself and de-stress, including meditation (even five minutes may be transformative), prayer, mindfulness, finding your happy place, getting pampered with a massage, acupuncture, reiki, and a mani-pedi. Try to have an orgasm at least once a week.

Employ supplements.

Birth control drastically reduces nutritional levels. The pill depletes several important minerals, including folate, vitamins B2, B6, and B12, vitamins C and E, as well as magnesium, selenium, and zinc. I advise taking more magnesium, omega-3 fatty acids, and a good multivitamin-mineral. I also advise taking a decent probiotic supplement and extra vitamin D if a blood test reveals you are deficient.

Rest well at night.

You can say goodbye to fantastic emotions and hormonal balance if you don’t get at least seven hours of sleep every night. Key hormones that control the menstrual cycle can fluctuate as a result of poor sleep hygiene, insomnia, and sleep loss. To restore your body, replenish your adrenals, thyroid, and hormones, and feel like an idol, you must get enough restorative sleep.

Pay attention to your liver.

Hormones that your body no longer requires, including synthetic hormones from the pill, are eliminated by your liver. Your liver continues to actively detoxify these hormones while you are taking the pill, but it suffers from nutrient inadequacies brought on by the pill’s interference with your body’s natural detoxification processes as well as the tablet’s direct effects on your liver. In order to restore your hormonal health, supporting the liver is a crucial first step. The two favourite methods for doing it are: Consider eating 3 to 6 cups of organic vegetables each day, along with at least 25 grammes of fibre.

Listen to your inner instinct.

Birth control pills alter the natural flora, creating an environment where dangerous bacteria and yeast can proliferate out of control. Additionally, the pill may cause digestive tract inflammation, which may lead to immunological dysregulation and an elevated risk of autoimmune illness. Leaky gut, also known as intestinal hyperpermeability, is similarly influenced by inflammation. Including foods like bone broth and vitamins like L-glutamine and omega-3 fatty acids in your diet will help your gut stay healthy.

REFERENCES:

For more details, kindly visit below.