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What are the medicines that can make you tired?

What are the medicines that can make you tired?

If you take a sleeping tablet, you should anticipate feeling weary, but other medications might also make you feel fatigued. One of the most prevalent adverse effects of both prescription and over-the-counter medications is this one.

Medications frequently influence neurotransmitters, which are brain chemicals, when they make you tired. They serve as a communication channel between your nerves. Some of them regulate your level of alertness or sleepiness.

It can be challenging to carry out daily tasks while you’re feeling fatigued. This emotion is common. In fact, one of the most frequent symptoms made to a primary care physician is weariness. It can affect up to 45% of people, and the cause is occasionally elusive.

Despite not being the only solution, some people may experience fatigue or sleepiness after taking drugs like propranolol (Inderal LA) and fluoxetine (Prozac). They are not the only ones, either.

Medications that causes tiredness and fatigue.

The following are a some of the most popular medications that might exhaust you:

Antihistamines.

Medications for allergies such as hydroxyzine (Vistaril, Atarax), diphenhydramine, and brompheniramine (Bromfed, Dimetapp) (Antivert). Sleeping medications also contain some of these antihistamines.

Antidepressants.

Tricyclics are one class of antidepressant that might leave you feeling worn out and sleepy. Amitriptyline (Elavil, Vanatrip), doxepin (Silenor, Sinequan), imipramine (Tofranil, Tofranil PM), and trimipramine are those that are more likely to do it than others (Surmontil).

Anti-anxiety drugs.

Depending on which benzodiazepine you take, you may experience weakness or drowsiness for a few hours to several days. Examples include alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and lorazepam (Ativan).

Blood pressure medications.

Beta-blockers, including propranolol hydrochloride (Inderal), metoprolol succinate (Toprol XL), metoprolol tartrate (Lopressor), and atenolol (Tenormin), to mention a few. They function by lowering your heart rate, which can wear you out.

Cancer treatment.

By altering the quantities of proteins and hormones in your body, certain cancer treatments might leave you feeling extremely exhausted. They harm or kill some normal cells while eliminating cancer cells. Your body then expends additional energy to repair or clean up the cells.

Gut medications.

You may feel tired after using medications for diarrhoea, motion sickness, or nausea.

Muscles relaxants.

The majority of muscle relaxants don’t directly affect your muscles. In order to relax the muscles, they instead focus on the nerves in your brain and spine. You can feel exhausted from their impacts on your nervous system. Carisoprodol (Soma) and cyclobenzaprine are examples of commonly used muscle relaxants (Flexeril).

Opioid pain medications.

Opioids mimic the effects of endorphins, which your body naturally produces to reduce pain. Fentanyl, oxycodone with aspirin (Percodan), oxycodone with acetaminophen (Percocet, Roxicet), morphine, oxymorphone (Opana, Opana ER), oxycodone (OxyContin, OxyIR), and hydrocodone and acetaminophen are some of the more popular ones (Lorcet, Lortab, Vicodin).

Seizure or epilepsy medications.

These drugs, also known as anticonvulsants, can affect your brain cells or the chemicals that your brain uses to deliver messages. Some of these medications, such as benzodiazepines, are also used to alleviate anxiety. Other frequent seizure drugs include phenobarbital, phenytoin (Dilantin, Phenytek), topiramate (Topamax), valproic acid, and carbamazepine (Tegretol/Tegretol XR/Carbatrol) (Depakene, Depakote).

What can we do?

Do not stop taking your medication even if it makes you feel fatigued. Other strategies to combat the negative effect and increase energy include:

  • Take a short walk or do some stretches to get some exercise.
  • Breathe deeply.
  • Consume some caffeinated beverages, such as coffee or tea.

Consult your physician or pharmacist to see if there are any “non-drowsy” alternatives to any over-the-counter medications you are now taking. To ensure that it won’t interfere with any other prescriptions you’re taking, it’s crucial to inquire.

You can get assistance from your doctor in managing any drug-related weariness. They could:

  • Switch medications.
  • Modify your dosage
  • instruct youself to take your medication at a different time, such as before bed or in the evening.
  • Give you a prescription for a drug to make you feel awake and aware.

Unless your doctor gives the all-clear, avoid taking any drugs that are designed to keep you awake.

REFERENCES:

  • https://www.webmd.com/drug-medication/medications-fatigue-and-sleepiness
  • https://www.goodrx.com/healthcare-access/medication-education/prescription-make-you-tired
  • https://www.prevention.com/health/g20476219/4-common-medications-that-are-making-you-tired/

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Top causes of Gastroparesis you need to know about.

Top causes of Gastroparesis you need to know about.

What is Gastroparesis?

Gastroparesis, which literally translates to “partial paralysis of the stomach,” is a condition where your stomach is unable to properly empty itself of food. If you have this problem, your muscles and injured nerves won’t work with their usual strength and coordination, which will hinder the passage of food through your digestive tract.

Long-term diabetics frequently have this syndrome, however it can also happen in other circumstances. Gastroparesis can be misdiagnosed and occasionally confused with an allergic reaction, heartburn, or an ulcer. The problem can be related to acid reflux in those without diabetes.

What causes gastroparesis?

Injuries to the nerves, including harm to the vagus nerve, can result in gastroparesis. The vagus nerve normally causes your stomach muscles to contract (tighten) in order to aid in the passage of food through your digestive system. Your vagus nerve is harmed by diabetes in cases of gastroparesis. As a result, food cannot pass from your stomach to your intestines because the muscles in your stomach and intestine are unable to function properly.

Gastroparesis can also result from:

  • surgery caused vagus nerve damage
  • a deficiency in thyroid hormone (hypothyroidism)
  • stomach virus infections (gastroenteritis)
  • medications, including some antidepressants and narcotics
  • Parkinson’s condition
  • a number of sclerosis
  • Rare diseases like scleroderma and amyloidosis (protein deposits in tissues and organs) (a connective tissue disorder that affects your skin, blood vessels, skeletal muscles, and internal organs)

Diabetic gastroparesis

Diabetes, notably diabetes that isn’t well-controlled, is a common factor in nervous system impairment that impairs digestion.

This is due to the fact that sustained high blood sugar levels can harm neurons, especially the vagus nerve, which regulates the passage of food through the digestive tract.

One of the most effective ways for diabetics to manage the symptoms of gastroparesis is to maintain healthy blood sugar levels by implementing dietary and lifestyle adjustments.

What are the symptoms of gastroparesis?

Dehydration and malnutrition can result from gastroparesis symptoms including vomiting and decreased appetite. Malnutrition and dehydration can lead to a wide range of issues, including:

  • Elevated electrolytes
  • reduction in blood pressure
  • elevated heart rate
  • quickly breathing
  • reduced urine production
  • a lowered immunological response
  • sluggish wound healing
  • muscular tremor

Food staying in the stomach for too long due to gastroparesis might lead to an overgrowth of microorganisms. Additionally, the meal has the potential to solidify into bezoars, which can clog the stomach and produce nausea and vomiting.

Keeping blood glucose levels under control is crucial for diabetics. It may be more difficult to control those levels if you have gastroparesis.

Should I change my diet if I have gastroparesis?

Changing your everyday eating habits is one of the best methods to help manage the symptoms of gastroparesis. For instance, you could consume six little meals throughout the day rather than three. By doing this, you will have less food in your stomach, which will make you feel less full and make it simpler for the food to pass through your system.

The texture of the dish is another crucial element. Your doctor might advise drinks and low-residue foods (you should eat applesauce instead of whole apples with intact skins). Additionally, you should stay away from fiber- and fat-rich foods because they can cause gastrointestinal problems (which is difficult to digest).

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What are the drugs that can cause Erectile dysfunction?

What are the drugs that can cause Erectile dysfunction?

Summary

Sexual dysfunction is a result of a variety of medical problems and treatments. Antihypertensives, antidepressants, antipsychotics, and antiandrogens are among the medications frequently implicated.

The doctor will be able to customise therapies for the patient and his or her partner by being aware of the potential for drug-induced sexual issues and their detrimental effects on adherence to treatment.

Good clinical treatment necessitates facilitating a conversation with the patient regarding sexual function and offering solutions to the issue.

Introduction

Sexual dysfunction in both men and women is a result of several prescription drug groups. A patient’s likelihood of not adhering increases if they experience drug-induced sexual dysfunction. Antipsychotics and antihypertensives have been found to have this effect. Less information is known on female or couple problems, and the literature has emphasised male sexual disorders.

Alcohol, opioids, stimulants, and hallucinogens are examples of recreational drugs that can alter sexual function. Alcohol consumption has a short-term impact on sexual desire by lowering inhibitions, but it also lowers performance and delays climax and ejaculation. Contrary to what their spouses frequently describe, many substance users claim to have greater sexual function.

The phases of sexual desire, arousal, and orgasm make up sexual function. Any of these periods might be problematic for both men and women. A person’s partner may also be impacted by low desire, lack of swelling and lubrication in women, erectile dysfunction, premature, retrograde, or absent ejaculation, anorgasmia, and painful sex.

Medications resulting in Erectile dysfunction

You might want to start by looking in your medication cabinet if you are having trouble getting or keeping an erection. Many prescription and over-the-counter medications have the potential to cause erectile dysfunction. While these medications may be used to treat an illness or condition, they can also have an impact on a man’s hormones, nervous system, and blood circulation, which might lead to ED or raise the risk of ED.

Below is a list of medications that could result in ED. To rule out any medications as a cause of, or contributor to, ED, talk to your doctor about the medications you are now taking.

Medicine to lower blood pressure

Although all blood pressure drugs have the potential to result in erectile dysfunction, “diuretics” (sometimes known as “water pills”) are the most likely to do so. Following are a few blood pressure drugs that frequently result in ED:

  • Chlorothiazide, chlorthalidone, and hydrochlorothiazide are examples of thiazide diuretics.
  • Furosemide, Torsemide, and Ethacrynic Acid are examples of loop diuretics.
  • Spironolactone
  • Clonidine
  • Guanethidine
  • Methyldopa
  • Lastly, Beta-blockers, another class of heart medication, carry a negligible risk of ED. Popular medications such as metoprolol (Lopressor), atenolol (Tenormin), propranolol (Inderal), and bisoprolol are among them (Zebeta).

There is some good news if you take one of these drugs and experience ED. ED is not frequently brought on by the following blood pressure medications:

  • ACE inhibitors such as lisinopril, benazepril, enalapril, ramipril, quinapril, and ramipril
  • Alpha-blockers such as doxazosin, prazosin, and terazosin

Cholesterol-lowering drugs

Contrary to popular belief, statins (drugs used to decrease cholesterol) such as atorvastatin, simvastatin, and rosuvastatin do not result in ED. Self-reported erectile function for men with ED who take statins for elevated cholesterol really improves by 25%. It’s a win-win situation because the statin also promotes heart and then brain health.

Antidepressants

Low sex drive and erectile dysfunction are frequently brought on by depression. However, a lot of antidepressants might worsen erectile dysfunction and low sex drive.

Examples of antidepressants that cause ED include the following:

  • SSRIs include sertraline, fluoxetine, citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), and paroxetine (Paxil) (Zoloft)
  • SNRIs include duloxetine, venlafaxine, and desvenlafaxine (Effexor, Pristiq) (Cymbalta)
  • MAOIs include tranylcypromine, phenelzine, and isocarboxazid (Marplan) (Parnate)
  • Amitriptyline, nortriptyline, and clomipramine are examples of tricyclic and tetracyclic antidepressants.

The most often prescribed antidepressants and those that are most likely to result in ED are SSRIs (selective serotonin reuptake inhibitors). This is unfortunate because SSRIs are some of the best available antidepressants.

The following antidepressants have a lower risk of causing erectile dysfunction:

  • Bupropion (Zyban) (Zyban)
  • Mirtazapine (Remeron) (Remeron)
  • Patches for selegiline (Emsam)

Finally, discuss this with your doctor if you believe your antidepressant is contributing to erectile dysfunction.

Antihistamines

Erectile dysfunction can also be brought on by antihistamines like Benadryl, Dramamine, and Phenergan. Histamine, a substance in the body that has a role in both allergic reactions and good erections, is blocked by antihistamines.

Acid reflux medications

Similar to antihistamines, some H2 blocker medications used to treat acid reflux can disrupt histamine and result in erectile dysfunction. Cimetidine (Tagamet), a medication in this class, carries the highest risk for ED, but ranitidine (Zantac) and famotidine (Pepcid) carry a lower risk.

Opioid pain medications

Opioids and ED go hand in hand as well. Long-term opiate use can cause low testosterone and erectile dysfunction. Medications that contain opioids include morphine, oxycodone, and hydrocodone.

Do not stop taking the medicine if you have ED and suspect it might be related to your prescription without first talking to your doctor. Your doctor might be able to recommend a different drug if the issue continues.

The following recreational and regularly misused drugs are among those that can induce or lead to ED:

  • Alcohol /Amphetamines
  • Barbiturates
  • Cocaine
  • Marijuana
  • Methadone
  • Nicotine /Opiates

ED is not frequently discussed, aside from the well-known negative effects that using and abusing these medicines can have. However, using these medications can result in ED. These medicines can seriously harm blood vessels and result in persistent ED in addition to affecting and frequently suppressing the central nervous system.

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How can some medications cause you erectile dysfunction?

How can some medications cause you erectile dysfunction?

What is Erectile dysfunction?

Erectile dysfunction is basically a disorder found in men which could be a sign of physical or psychological condition. The symptoms associated with this disorder is found in men’s reproductive organ i.e. inability to keep an erection firmer and longer enough during a sexual activity.

Erectile dysfunction is a treatable disorder which includes many possible methods such as natural remedies, alternative medicine, and prescription drugs. In this article, let us discuss about some faster ways to treat this disorder.

There are many men who experience erectile dysfunction occasionally because of stress, fatigue, alcohol, or emotional issues, but 25% of men have recurring episodes of the disorder. People dealing with erectile dysfunction will be:

  • Unable to achieve erection at anytime needed.
  • might achieve erection sometime but not when needed like during sexual activity.
  • might able to achieve erection when needed but not long enough

Causes of Erectile dysfunction

Arousal of male sexual desire is a complex process that involves the brain, hormones, emotions, nerves, muscles, and blood vessels. There are a number of conditions that can cause erectile dysfunction. Erectile dysfunction can also be caused or worsened by stress and mental health concerns.

The cause of erectile dysfunction can be a combination of physical and psychological factors. The anxiety surrounding maintaining an erection might be caused by a minor physical condition that slows your sexual response. A person experiencing anxiety may suffer from erectile dysfunction or have it worsened.

Can medicines cause Erectile dysfunction?

There are several factors that can cause or contribute to erectile dysfunction. As an example, a person might take medications. There is a possibility that medicines that affect the blood flow to the sexual organs and the sex drive may increase the risk of Erectile Dysfunction.

In older men, it is more likely that they are taking some kind of medication, which contributes to erectile dysfunction. An estimated 25% of cases of ED are related to medication side effects, according to the Harvard Special Health Report on Erectile Dysfunction.

Take a look at your medicine cabinet if you are having problems achieving or maintaining an erection. Erectile dysfunction may be caused by many prescription medications and over-the-counter medications. Despite the fact that these drugs may be used to treat certain disorders, they can also affect a man’s hormones, nerves, or blood circulation, which can result in ED or increase the risk of it.

Medicines that may cause Erectile dysfunction

1. Blood pressure medicines

Usually, people with heart disease are more likely to take blood pressure medicines. The most common type of medicine that may lead to erectile dysfunction are blood pressure medicine, especially the water pills. Some blood pressure medications that commonly cause ED incudes:

  • Thiazide diuretics like chlorothiazide, chlorthalidone and hydrochlorothiazide
  • Loop diuretics like furosemide, torasemide and ethacrynic acid
  • Spironolactone
  • Clonidine
  • Guanethidine
  • Methyldopa

Beta-blockers, another type of heart medicine, have a small risk of ED. Some of these drugs include metoprolol (Lopressor), atenolol (Tenormin), propranolol (Inderal) and bisoprolol (Zebeta). These medications aren’t all bad for people with ED who take them. 

2. Antidepressants

There is a strong correlation between depression and low sexual drive and erectile dysfunction. The problem with many antidepressants is that they can cause low sexual drive and erectile dysfunction, or worsen them.  Some of such antidepressants include:

  • SSRIs: citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft)
  • SNRIs: venlafaxine (Effexor), desvenlafaxine (Pristiq), duloxetine (Cymbalta)
  • MAOIs: isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate)
  • Tricyclic and tetracyclic antidepressants: amitriptyline, nortriptyline, clomipramine

Antidepressants such as selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed and most likely to cause ED. However, they are the most effective medications against depression.

Some of the antidepressants that are less likely to cause ED includes:

  • Bupropion (Zyban)
  • Mirtazapine (Remeron)
  • Selegiline patches (Emsam)

3. Antihistamines

Antihistamines like Benadryl, Dramamine, and Phenergan can also cause erectile dysfunction. The action of antihistamines is to block the release of histamine from the body, a chemical that is involved in allergic reactions and healthy erections.

4. Acid reflux medications

In the same way as antihistamines, certain acid reflux drugs called H2 blockers may also inhibit histamine production and lead to erectile dysfunction. This class of drugs is characterized by the highest risk for ED of cimetidine (Tagamet), and the lowest risk for ED of ranitidine (Zantac) and famotidine (Pepcid).

5. Opioid pain medications

There is also a connection between opioids and ED. Low testosterone levels and erectile dysfunction are possible side effects of long-term opioid use. The three most common opioid medications are hydrocodone, oxycodone, and morphine.

6. Antiepileptics

It is common for patients on antiepileptic drugs to experience sexual dysfunction. It has been reported that gabapentin and topiramate are associated with orgasmic dysfunction in both men and women, and reduced libido in women.

7. Immunosuppressants

An immunosuppressant reduces the immune system’s activity. It is usually given to the person to help control an autoimmune condition or during organ transplant surgery to prevent organ rejection. A potential side effects of this drug category is impaired sexual function. Medicines include:

  • sirolimus
  • everolimus
  • tacrolimus
  • cyclosporine

Always inform the doctor if you notice any medication causing you erectile dysfunction. The medication might be discontinued or other method could to be used to counter ED along with ongoing medical condition.

The above list and categories of medicine are not every possible medication that must be taken of to prevent ED. However, if you are dealing with ED, there is 25% chance that it is caused due to your meds. If you think that your meds are causing you erectile dysfunction, it is always advisable to speak about it to your doctor.

REFERENCES:

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