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Important variation between Genital herpes and Oral herpes.

Important variation between Genital herpes and Oral herpes.

What is herpes simplex?

Genital and oral herpes are viral infections brought on by the herpes simplex virus, generally known as HSV. Many people have HSV that is asymptomatic, which means they have the virus but have never experienced a herpes outbreak or active episode.

Others may occasionally get sores or blisters that are tiny and filled with fluid. Although they can emerge on your hands, fingers, or other regions of your body, these blisters most frequently develop on your genitalia, mouth, and lips.

HSV can be spread through sexual contact, but there are other ways to spread the virus. Herpes is stigmatised a lot, yet it’s actually quite common and nothing to be ashamed of.

The World Health Organization has provided estimates that show:

  • In 2016, over 67% of people under 50 worldwide had oral or genital HSV-1.
  • In 2016, approximately 13% of individuals aged 15 to 49 had HSV-2.

According to other studies, by the time adults are in their 50s, almost 90% of them carry HSV-1 antibodies. Herpes still has no known cure, however antivirals and natural therapies might lessen the intensity of symptoms. Less frequent herpes outbreaks may also result from antiviral therapy.

The herpes simplex virus comes in two primary varieties: HSV-1(Genital herpes) and HSV-2(Oral herpes).

Genital Herpes

A typical sexually transmitted infection is genital herpes (STI). Genital herpes is brought on by the herpes simplex virus (HSV). During sexual activity, skin-to-skin contact can frequently spread genital herpes.

Some virus-infected individuals may not even exhibit any symptoms or may have extremely minor ones. They still have the ability to spread the infection. Others experience discomfort, itchiness, and ulcers in their mouth, anus, or genitalia.

Herpes genitalis cannot be cured. Symptoms frequently return after the initial outbreak. Drugs can reduce symptoms. It also lessens the chance of spreading infection. A genital herpes infection can be stopped from spreading with the aid of condoms.

Oral Herpes

Herpes simplex virus type 1 frequently causes the infection known as oral herpes (HSV-1). Oral herpes symptoms most frequently manifest as “fever blisters” and “cold sores,” respectively, on or near the lips. However, oral herpes is not always restricted to one region.

Some people may experience symptoms that manifest between the top lip, on the nose or inside it, or on the chin or cheek. Herpes is referred to as oral-facial herpes in these cases. Most likely, you have witnessed an oral herpes outbreak previously.


Symptoms of Oral herpes

The worst stage of oral herpes is typically the initial (primary) infection. It may result in severe flu-like symptoms, such as headache and enlarged lymph nodes. Some individuals, however, have no symptoms at all. Sores on, around, and in the mouth can develop during the early infection.

Recurring infections typically have considerably milder symptoms, and the sores almost always appear on the lips’ outer margins. Some people never experience another infection after the initial one. The most typical warning signs and symptoms of recurrent oral herpes simplex infection are listed below.

  • The location where the infection will first manifest itself may experience initial redness, swelling, heat/pain, or itching.
  • Blisters that hurt and are packed with fluid might develop on the lips or under the nose. The fluid and blisters are very contagious.
  • The blisters will start to bleed and scab over.
  • The sores will start to crust up and heal after four to six days.

An oral herpes outbreak might mimic other diseases or health issues in terms of its signs and symptoms. For a precise diagnosis, always speak with your doctor.

Symptoms of Genital herpes

Most HSV carriers are unaware of their infection. They could have no symptoms at all or just very minor ones.

Within two to twelve days of viral exposure, symptoms appear. They may consist of:

  • Itching or discomfort at the genitalia
  • Blisters or little pimples near the genitals, anus, or mouth
  • Discouraging ulcers that develop when blisters break and leak or bleed
  • As the ulcers heal, scabs appear.
  • unpleasant urination
  • discharge from the urethra, the tube that allows the body to excrete pee
  • Expulsion from the vagina

You might frequently have flu-like symptoms during the initial outbreak, such as:

  • Fever
  • Headache
  • Body pains
  • Groin lymph nodes that are swollen

What causes herpes simplex?


HSV-1, or oral herpes, can be contracted or transmitted through close contact with a herpes sore, saliva, or other bodily secretions when an episode is in progress. Someone who comes into contact with the infection site directly from you could catch the virus if you’re shedding it.

Direct contact examples include:

  • kissing
  • verbal sex
  • supplementary skin-to-skin contact

In other words, you might catch the virus if you contact your partner’s cold sore and then quickly touch your own face or genitalia. Many youngsters get the virus from an adult who has a cold sore after being kissed or handled on the face.

In principle, the virus can spread through sharing razors, drinkware, and eating utensils, but this is extremely unlikely because, according to earlier estimations, the virus can only survive outside your body for a short period of time (a few hours to a few days).


Similar to HSV-1, HSV-2, often known as genital herpes, can be contracted or transmitted through direct contact with a herpes sore, saliva, or other bodily secretions while an episode is in progress. Additionally, HSV-2 can spread during viral shedding.

Direct communication may involve:

  • kissing
  • verbal sex
  • while having a sexual encounter, sharing sex toys
  • invasive sex
  • at the infection site, more skin-to-skin contact

Remember that both kinds of the virus can produce oral or genital episodes, despite the fact that many people associate HSV-1 with oral herpes and HSV-2 with genital herpes.

When to see a doctor

It can be challenging to determine whether to seek medical attention for a diagnosis and treatment because a person with herpes may not exhibit any symptoms.

As soon as someone notices sores on or around their genitalia, Planned Parenthood advises that individual to see a doctor. Syphilis is one STI that can have similar symptoms but calls for a different course of action. The American Sexual Health Association also advises getting a culture of any lesion or cold sore one detects before visiting a doctor.

Before visiting a doctor, people might choose to perform an at-home STI test. At-home tests should not, however, be used in place of expert diagnosis and care.


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What happens when you take P-shot for erectile dysfunction?

What happens when you take P-shot for erectile dysfunction?

Erectile dysfunction is basically a disorder found in men which could be a sign of physical or psychological condition. The symptoms associated with this disorder is found in men’s reproductive organ i.e. inability to keep an erection firmer and longer enough during a sexual activity.

There are many men who experience erectile dysfunction occasionally because of stress, fatigue, alcohol, or emotional issues, but 25% of men have recurring episodes of the disorder. People dealing with erectile dysfunction will be:

  • Unable to achieve erection at anytime needed.
  • might achieve erection sometime but not when needed like during sexual activity.
  • might able to achieve erection when needed but not long enough

You are not alone if you experience erectile dysfunction (ED). In the US, an estimated 18 million men struggle from ED. Despite being prevalent, ED can have a negative impact on your close relationships, as well as your physical and mental health. Fortunately, it has been demonstrated that most men can successfully treat ED with drugs that have been approved by the Food and Drug Administration (FDA).

The P-shot

Platelet-rich plasma (PRP), which is used in the P-Shot, is drawn from your blood and injected into your penis. In order to boost tissue growth and, ostensibly, improve your erections, your doctor injects your own cells and tissues into your penile tissues.

The Priapus Shot is the most common variant. Dr. Charles Runels (of Kardashian vampire facial fame) was the first to utilise this moniker, which was derived after the Greek deity of sexual health, and it quickly gained popularity.

The P-Shot is based on PRP therapy, which has been investigated for the treatment of chronic health disorders and is used to recuperate from muscle and joint injuries. It is regarded as an experimental treatment in all circumstances.

In essence, the P-Shot has been utilised as an alternative therapy in situations like:

  • erection problems (ED)
  • sclerosus lichen
  • Scar tissue caused by Peyronie’s disease causes the penis to curve when it is upright.
  • Penis improvement
  • increase of orgasm, performance, and general sexual function

How does it work?

The only evidence we have is anecdotal. Nobody understands why it works to improve sexual function, whether it can be repeated, what the results are, or how safe it is.

Orgasms can occur (or not) for a variety of physiological, psychological, and emotional causes. It’s possible that a shot won’t affect the underlying cause of your orgasmic ability.

The advantages of this therapy on sexual performance may be linked to: Dr. Richard Gaines, who offers the P-Shot along with other therapies at his LifeGaines office, claims that:

  • Possibility of engaging in sexual activity on the day of the operation
  • higher sensitivity
  • greater assurance
  • enhanced length and girth
  • rapid start of the effects
  • healthier and better sex
  • better personal connections

What to expect during operation?

You can come in, get the P-Shot done, and leave later that day because it is an outpatient surgery. To give yourself enough time to complete it, you might wish to skip a day of work or other obligations, although this isn’t required.

You’ll probably be instructed to lay down on a table when you get to the facility and wait for the doctor to start. After starting the process, the physician or assistant will:

  • Apply a numbing cream or ointment to the vaginal region, and a local anaesthetic will be administered to numb the surrounding area as well.
  • Take some blood from your body and place it in a test tube, usually from your arm or another non-invasive location.
  • Centrifuge the test tube for a few minutes to separate the blood’s constituent parts and isolate the platelet-rich plasma (PRP).
  • PRP should be taken out of the testing tube fluid and placed into two different syringes for injection.
  • PRP should be injected into the clitoris, penile shaft, or Gräfenberg (G) spot. With perhaps four to five different injections, this is finished in a short period of time.
  • Giving a penis pump to patients who had a penile shaft injection. By doing so, you may make sure the PRP is operating as planned and draw blood into the penis. Over a few weeks, you might be required to perform this task on your own once a day for ten minutes. However, overusing one might weaken erections by harming the elastic tissue in the penis.

You’re done now! After that, you’ll probably be able to return home in an hour or less.

Side effects and complications

Following the injection, you may experience a few minor side effects that should subside in four to six days, including:

  • swelling
  • redness
  • bruises

Some uncommon issues could be:

  • infection
  • scarring
  • cold sore outbreaks if you’ve already had the herpes simplex virus


Additional study is required to back up the P-Shot. Talk in-depth with a provider if you want to give it a try. Additionally, think about speaking with a separate physician who is unaffiliated with the P-Shot provider. Remember that your mental and emotional well-being can have an impact on the blood flow, hormones, and physical states that create your erections and orgasms.

Investigate any health problems that might be affecting your sexual function if the P-Shot isn’t producing any results for you. You could also seek the advice of a therapist, counsellor, or sexual health expert who can help you identify the obstacles standing in the way of your sexual fulfilment.


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Can Cycling increases the risk of Erectile dysfunction?

Can Cycling increases the risk of Erectile dysfunction?

Cycling is a well-liked kind of aerobic exercise that tones the legs while burning calories. A third or more of Americans ride bikes. Some people ride bikes for amusement on occasion, while others are more serious riders who pedal for several hours each day.

The unexpected consequence of spending too much time on a bike seat, however, is that persons who have a penis and cycle may face erection issues.

It’s hardly news that cycling can cause erection issues. When he observed, “The frequent jolting on their horses unfits them for intercourse,” the Greek physician Hippocrates actually recognised sexual problems in male horseback riders.

Erectile dysfunction

The inability to achieve and maintain an erection strong enough for intercourse is known as erectile dysfunction, commonly referred to as impotence. Sometimes having erection problems is not a cause for alarm. However, if erectile dysfunction persists, it can worsen your stress levels, undermine your confidence, and cause relationship issues. It may also detract from your desire for sexual activity.

The percentage of bikers who have experienced genital numbness while cycling ranges from 50 to 91%. This numbness results from a rider’s saddle compressing their perineum, which is a densely populated area of blood vessels and nerves located between their anus and genitalia.

Here are several reasons why cycling may interfere with getting an erection and some tips for avoiding this problem.

How does cycling affect erections?

Cycling may cause erectile dysfunction because the pressure of sitting on the saddle may be pressing against the nerves in your private areas, which can cause them to become painful. This can lead to erectile dysfunction because it’s bad for your fertility.

The perineum, which is the region between the genitalia and the anus, is constantly compressed by the seat when riding. This pressure has the potential to damage nerves and momentarily reduce blood flow. This may eventually result in erectile dysfunction as well as tingling or numbness in the penis.

Nerve impulses from the brain arouse the penis in order for a guy to get an erection. These nerve signals cause blood vessels to relax, resulting in more blood flowing into the penis through the arteries. Any issue with the blood vessels, nerves, or both may prevent you from getting an erection. The term for this is erectile dysfunction (ED).

The perineum, a region that lies between your anus and penis, gets compressed when you ride a bike for extended periods of time. Your penis receives oxygen-rich blood and feeling from the arteries and nerves that make up your perineum.

Men who ride their bikes for long periods of time have complained of numbness and difficulty getting an erection. According to experts, ED is caused by arteries and nerves becoming entrapped between the rider’s pelvic bones and the bicycle’s tight seat.

What research says

Male bikers should regularly stand up when biking, according to research from the Wroclaw Medical University in Poland, to avoid erectile dysfunction. Every ten minutes, people should stand on the pedals, according to the research. The study notes that, in addition to private parts being squashed on the saddle, bad riding technique or choosing the wrong kind of bike can also result in genital numbness.

A Harvard Special Health Report further states that riding a bike might harm the nerves and constrict the arteries in the penis, which can cause erectile dysfunction. According to the study, men who cycled for more than three hours each week were at the greatest risk.

How to reduce your risk of ED

You can still ride for fun and exercise while maintaining your love life with a few adjustments. You can make the following changes to lessen your risk of developing ED:

  • Adjust your seat – Replace your slender bicycle seat with one that is wider and has more padding to support your perineum. Additionally, to lessen strain, select a seat without a nose (it will be more rectangular in shape).
  • Lower the handlebar -. Your perineum will feel less pressure if you lean forward and lift your bottom off the seat.
  • Cushioned biking shorts – You will have additional security as a result of this.
  • Reduce the amount of training – Reduce the number of hours you cycle.
  • During lengthy rides, take frequent breaks – Periodically move around or stand on the pedals.
  • Use a recumbent bike instead – Reclining is better for your perineum if you want to spend a lot of time on the bicycle.
  • Change up your workout routine – Alternate between jogging, swimming, and other aerobic exercises in place of only cycling. Include cycling in a comprehensive exercise regimen.

Stop riding for a bit if you experience any discomfort or numbness in the region between your rectum and scrotum.

Other risk factors

Other than cycling, a number of other risk factors can result in erectile dysfunction. Tobacco use, which reduces blood flow, obesity, medical procedures like prostate surgery or radiation therapy for cancer, antidepressant pills, stress, anxiety, or depression, and heavy or regular drug and/or alcohol use are a few examples of these.


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What’s the link between Cancer treatment and ED?

What’s the link between Cancer treatment and ED?

Your sex life may change as a result of physical and psychological side effects of cancer treatment. These alterations are referred to as “sexual side effects” by doctors. They consist of modifications to your sex interest and your capacity for sexual action.

Physical, mental, or emotional adverse effects from sexual activity are possible. Your attitude, sense of wellbeing, energy level, and body image can all be impacted by cancer therapy. All of these factors can influence your sexual life.

Whether your cancer diagnosis and/or treatment may alter your sexual life is something you should discuss with your medical team. If at all possible, do this before beginning treatment. The optimal form of treatment for you can be impacted by it. Getting a second opinion might be wise if you are extremely concerned.

Sexual problem during cancer

Your sexual health may change as a result of having cancer or the therapy for it, either during or after treatment. These modifications could go or stay put. Everyone is unique.

Treatments that directly affect your genital organs are more likely to have physical side effects. Prostate, bladder, and testicular cancer treatments, for instance, are more likely than some other cancer treatments to have an impact on your capacity to physically engage in sexual activity. However, leukaemia treatment, for example, might also make you feel exhausted or ill, which can reduce your interest in sex. This is why discussing your unique diagnosis and what to expect with your medical team can be beneficial.

The following are examples of possible sexual side effects:

  • less sex-related interest
  • having trouble attaining or maintaining an erection long enough to engage in penetration. Other terms for this issue include “erectile dysfunction” and “ED.”
  • Orgasming before you’re ready is known as premature ejaculation.
  • urinating (peeing) while having an orgasm.
  • having a “dry” orgasm in which no sperm emerges. This can occur if semen exits the penis instead of flowing backward into the bladder.
  • suffering when having sex.

Inform your medical staff if you experience any of these issues before starting therapy. They might be able to assist or stop the difficulties from growing worse if they are aware of the issue. Additionally, during or after treatment, let your medical team know if you have any new issues or changes in your sexual health.

Treatments that can cause sexual problems

Surgery – The nerves that regulate erections can be harmed during procedures on the prostate, testicles, bladder, colon, and/or rectum. Consult your surgeon on “nerve-sparing” procedures. Additionally, surgery can result in “dry” ejaculation. You might find this upsetting or you might not.

Radiation treatment – ED may result after radiation therapy administered to the pelvis, which is the region around the hips. This may occur between six months and two years following the treatment. In two to three years, it might disappear or become better. What to do when you have ED should be discussed with your doctor.

Chemotherapy – Chemotherapy side effects can have an impact on your mood, sense of self, and sexual attraction. Weight gain or loss, nausea, vomiting, and diarrhoea are possible side effects. Additionally, you can stop having erections, but this normally returns with time. Any medication, including targeted therapy or immunotherapy, that is a part of your treatment plan should be discussed with your doctor for any potential sexual side effects.

Hormone treatment – Some prostate cancer treatments aim to reduce the amount of testosterone your body produces. Although it is done to treat the cancer, this may result in ED, reduced sex drive, and difficulties achieving an orgasm.


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What are the best medicines for ED without side-effects?

What are the best medicines for ED without side-effects?

What is erectile dysfunction?

Erectile dysfunction is basically a disorder found in men which could be a sign of physical or psychological condition. The symptoms associated with this disorder is found in men’s reproductive organ. It is an inability to keep an erection firmer and longer enough during a sexual activity.

There are many men who experience erectile dysfunction occasionally because of stress, fatigue, alcohol, or emotional issues, but 25% of men have recurring episodes of the disorder. People dealing with erectile dysfunction will be:

  • Unable to achieve erection at anytime needed.
  • might achieve erection sometime but not when needed like during sexual activity.
  • might able to achieve erection when needed but not long enough


You are not alone if you experience erectile dysfunction (ED). In the US, an estimated 18 million men struggle from ED. Despite being prevalent, ED can have a negative impact on your close relationships, as well as your physical and mental health. Fortunately, it has been demonstrated that most men can successfully treat ED with drugs that have been approved by the Food and Drug Administration (FDA).

Lets discuss some of the most popular FDA-approved drugs in this post, along with each one’s dosage, price, and potential adverse effects. I’ll also go through the duration of each prescription, the safest medications, and the medical issues that the medication may effect.

The majority of men may treat ED safely and effectively using ED medicines. Since prescriptions are required for all medications, speaking with your doctor will help you decide which, if any, is best for you.

How Does ED Medication Work?

The initial line of treatment for erectile dysfunction is frequently oral medicines. These drugs perform well and have few adverse effects for the majority of men who struggle to maintain an erection strong enough for intercourse (erectile dysfunction).

Oral drugs such as sildenafil (Viagra), vardenafil (Levitra, Staxyn), tadalafil (Cialis), and avanafil (Stendra) work to treat erectile dysfunction by boosting the effects of nitric oxide, a substance your body naturally generates that relaxes the penile muscles. As a result of the increased blood flow, you can respond to sexual stimulation by getting an erection.

ED drugs are safe when used by healthy people as prescribed and may help men have more fulfilling sexual experiences.

How oral medications differ

Each oral drug has a somewhat different chemical composition even though they all function in a similar fashion. These insignificant variations have an impact on how each prescription functions, including how quickly it takes action and wears off as well as any potential side effects. These elements, together with any additional medical issues you may have and any drug interactions, will be taken into account by your doctor.

  • Sildenafil (Viagra) – One hour prior to having sex, take this drug on an empty stomach for best results. If you suffer from mild to moderate erectile dysfunction, it remains effective for at least four to five hours.
  • Vardenafil (Levitra, Staxyn) – This medicine can be taken with or without food and is most effective when taken an hour prior to intercourse. It could not absorb as quickly if you eat a meal that is high in fat. If you have mild to severe erectile dysfunction, vadenafil will work for at least four to five hours. A more recent medicine formulation that dissolves on the tongue might function more quickly than a pill that you swallow.
  • Tadalafil (Cialis) – This drug should be consumed one to two hours prior to having intercourse, with or without meals. For up to 36 hours, it works. It can be consumed either in a little daily dose or a bigger quantity if required.
  • Avanafil (Stendra) – Depending on the dosage, this medicine may be taken with or without food 30 minutes prior to sexual activity. It might endure for six hours.

The American College of Physicians advises making the decision depending on your preferences, including the cost, simplicity of use, duration of the drug’s benefits, and adverse effects because both medications are similarly effective. Sildenafil, vardenafil, and tadalafil are all available in generic form.

Are Oral medicines unsafe?

Get your doctor’s approval prior to taking any erectile dysfunction medicine. If any of the following apply to you, erectile dysfunction drugs may not work or may be hazardous.

  • Take nitrate medications, which are frequently prescribed for angina (chest discomfort), include nitroglycerin (Nitro-Dur, Nitrostat, etc.), isosorbide mononitrate (Monoket), and isosorbide dinitrate.
  • possess either uncontrolled high blood pressure or extremely low blood pressure (hypotension) (hypertension)
  • have a serious liver condition
  • a renal condition that necessitates dialysis

Side effects of ED medications

The majority of guys who take oral erectile dysfunction drugs don’t have any issues with side effects. When side effects do materialise, they may comprise:

  • Flushing /Headache /Indigestion
  • A blue tint to the eyesight, sensitivity to light, or impaired vision are some examples of visual alterations.
  • runny or stuffed nose
  • back ache

Rarely, more severe side effects can develop, such as: loss of eyesight or hearing. Following the use of one of these drugs, some men experienced an unexpected loss of hearing or eyesight. It is unclear, however, whether vision or hearing loss was a direct result of using the medicine or was brought on by a pre-existing illness. Seek immediate medical assistance if you’re taking an oral erectile dysfunction prescription and experience a sudden loss of hearing or vision.


Erectile dysfunction medicines are generlally safe and effective when treated with proper precaution and prescription provided by the health rpofessional. However as per comparative studies and research on these ED medicines, the Boston University School of Medicine claims that vardenafil (Levitra), which is 10 times more biochemically active than sildenafil (Viagra), may have the lowest risk of adverse effects because it can induce erections with a smaller dose.


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Is Norethisterone good to treat gynecological disorders?

Is Norethisterone good to treat gynecological disorders?

Gynecological Disorders

A woman’s reproductive organs undergo continuous change from puberty to menopause due to sexual activity, pregnancy, age, natural processes, etc. Gynecology is the branch of medicine that deals with the condition female reproductive systems (vagina, uterus, and ovaries).

A gynaecological disorder is a condition that affects the female reproductive organs. It including the breasts, the uterus, the ovaries, the fallopian tubes, the vagina, and the vulva. Almost every woman will experience a gynaecological problem at some point in her life. It may be disastrous or insignificant.

Types of Gynecological Disorders

There are many different tpes of Gynecological Disorders found in wome. Some of the most common types of disorder include,

  • PCOS(Polycystic ovary syndrome) – The most frequent reason for anovulatory infertility is PCOS. Women who have PCOS are more likely to develop a number od medical conditions. It includes endometrial cancer, endometrial hyperplasia, metabolic syndrome, type 2 diabetes, cardiovascular disease, obesity, obstructive sleep apnea, and mood problems.
  • Endometriosis – About 10% of women of reproductive age are affected by endometriosis, which significantly contributes to the formation of pelvic adhesions, infertility, ectopic pregnancy, and persistent pelvic pain.
  • Uterine Fibroids (leiomyomata) -The most frequent benign gynecologic tumour in women, uterine fibroids (leiomyomata) are linked to a number of harmful health outcomes, such as irregular uterine bleeding, pelvic pain, infertility, miscarriage, and preterm childbirth.
  • Vaginitis – Any condition that results in swelling or inflammation of the vulva and the vagina is referred to as vaginitis. Yeast infections, bacterial vaginosis, non-infectious vaginitis, and vaginitis that is transmitted through sexual contact are common types of vaginitis.
  • Menstrual Disorders – Irregular or heavy menstrual bleeding affects quality of life and can be a sign of underlying gynecologic diseases including endometrial polyps, uterine fibroids, or anovulatory disorders.


Norethisterone is a medical drug available to us under the name Noriday which belongs to a class of medication called Progestins. This medicine is used for several women reproduction related disorders such as painful periods, premenstrual tension, breast cancer, endometriosis and also for the treatment of gynecological disorders.

How to use?

Norethisterone is available to us in a form of pill that must be taken by mouth with or without food as per your doctor’s prescription. It is usually taken once a day daily. The dosage and length of the treatment is based on your medical condition, response to the treatment and other medicine that you may be taking for the same or different reason. Swallow the tablet whole rather than chewing or crushing it in your mouth as it may release all the drug in your mouth which increases the risk of side effects.

Your doctor may start you with a low dose which will increase gradually. Take the medicine at the same time daily to get the most benefits from it. Do not increase your dose or take it more often than prescribed as this may also increase the risk of side effects without any improvement in your condition. Discuss all the other medicines that you might be taking along with  Norethisterone for the same or different reasons. Follow the medical prescription carefully and inform your doctor in case of any exception or confusion.

Side Effects of Norethisterone

Common side effects observed while medicating with Ibandronate are nausea, vomiting, headache, weight gain, bloating or breast tenderness, may occur. Inform your doctor if these conditions persist or get worse.

There are some serious side effects which must be informed to the doctor right away if observed such as lumps in the breast, mental/mood changes, severe stomach/abdominal pain, unusual changes in vaginal bleeding, dark urine, yellowing eyes/skin, etc. 

There are also some severe allergic reactions involved with these medications which require immediate medical attention if observed such as rash, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness, chest/jaw/left arm pain, confusion, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, trouble speaking, sudden shortness of breath/rapid breathing, unusual headache, unusual sweating, weakness on one side of the body, vision problems/changes, etc.

Precaution before using Norethisterone

  • If you have any allergies, including those to other progestins or norethindrone, let your doctor or pharmacist know before using this drug. Inactive chemicals in this product have the potential to trigger allergic reactions or other issues. To learn more, speak with your pharmacist.
  • Inform your doctor or pharmacist of your medical history before taking this medication, especially of any of the following conditions such as blood clots (for example, in the legs, eyes, or lungs), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, abnormal breast exam, cancer (especially endometrial or breast cancer), low levels of “good” cholesterol (HDL), depression, diabetes, severe headaches/migraines, heart problems (such as heart valve disease, irregular heartbeat, Jaundice, liver disease (including tumours), unexplained vaginal bleeding, history of yellowing of the eyes or skin (jaundice) during pregnancy or while using hormonal birth control (such as pills or a patch).
  • Inform your surgeon or dentist of all the products you use prior to surgery (including prescription drugs, nonprescription drugs, and herbal products).
  • Your face and skin may develop blotchy, dark spots as a result of this drug (melasma). This effect could get worse in the sun. Keep sun exposure to a minimum. Avoid using sunlamps and tanning booths. When outdoors, wear protective gear and sunscreen.
  • Pregnancy should not be the time to use this drug. Inform your doctor as soon as possible if you become pregnant or suspect that you may be pregnant.
  • Small doses of this medicine may enter breast milk and cause unfavourable effects on a nursing newborn. Before breastfeeding, speak with your doctor.

Norethisterone effects on Gynecological Disorders

  • With regard to treating dysmenorrhea, causing amenorrhea for at least six months, and reducing the size of ovarian endometriomas, the current data showed that NET was effective.
  • Progestins have anti-inflammatory and anti-angiogenic effect in endometriotic tissues and do not raise the risk of thrombosis. In endometriosis, NET and DNG both seem to be equally effective at reducing pain and the size of lesions. DNG is anti-androgenic, but NET also exhibits this property. These two progestins lack the strong glucocorticoid or anti-mineralcorticoid effects that many other hormonal medications have. Even progestins by themselves may help in bone development. Because NET is partially converted to estrogens, this may be an advantage over DNG.

In conclusion, the available evidence points to NET as a viable treatment for endometriosis-related dysmenorrhea and for shrinking ovarian endometriomas. Oral progestins alone can be used at any age, have very few adverse effects, do not increase the risk of thrombosis, and are capable of suppressing ovulation and causing amenorrhea.


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